GUY MASSICOTTE, PhD

based in Trois-Rivières (Québec) Canada

Dr. Massicotte is interested at understanding the biochemical mechanisms of normal and pathological synaptic plasticity. Attention is presently focussed on the role of lipases and their metabolites in controlling hippocampal synaptic plasticity (i.e. long-term potentiation; LTP). His work also includes elucidation of the role for PLA2 in regulating glutamate receptor function. Finally, attention is given at understanding the role of apolipoprotein E in LTP defects during ageing.

Key words: phospholipases, phospholipids, long-term potentiation, hippocampus, apolipoproteins, glutamate, AMPA, NMDA

Dr. Massicotte articles at PubMed | Dr. Massicotte editorial contact