Neurobiol Lipids 6, 3 (21 October 2007) find out how to cite this article or link to a particular abstract

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NEUROBIOLOGY OF LIPIDS SESSIONS 2007

Published online: 21 October, 2007 | Article readership

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This article alerts interested readers about neurobiology of lipids sessions of the 37th Society for Neuroscience (SfN) annual meeting, 3-7 November, 2007, San Diego, California. The abstracts were retrieved from the SfN web based abstract system as a result of the search for the key words cholesterol, phospholipid, lipoprotein, apolipoprotein, fatty acid, lipid peroxidation in abstract title or abstract text. Every abstract reference includes day/time, program number, presentation type (poster or slide show), location, authors list, authors' affiliation(s), abstract title, and the link to abstract text at the abstractsonline.com web site.

Note to readers: Please note that the presented list of abstracts may omit certain sessions due to search terms difference. This article thus does not aim to substitute your own search for Neuroscience 2007 abstracts at the AbstractsOnline web site, the online host of the SfN Annual Meeting abstracts 2007. If you notice an omission, please let us know.

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Disclaimer: the appearance of an abstract in this article is not an endorsement or approval of an abstract experimental/scientific content/conclusion. Within each category sessions are listed in the order of the assigned SFN program numbers.

	Further reading icons provide URL links to further/related reading suggested by abstract authors and/or NoL editors
	Editors' choice icons (when/if article is updated with editors' choice selection) will represent the noteworthy abstracts' selection of editors voted by the update date.

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

1. (11.10) TRO19622 is well tolerated and achieves target plasma concentrations in a Phase 1b study in ALS patients (Saturday, Nov 3 2007 3:15 PM - 3:30 PM) Abstract J.-L. ABITBOL1, A. VERSCHUEREN2, L. LACOMBLEZ3, V. CUVIER1, E. JOUVE2, *R. M. PRUSS1, O. BLIN2, V. MEININGER3, J. POUGET2; 1Res. &Develop., TROPHOS, Marseille Cedex 9, France; 2CPCET and Clinique de Neurologie Hôpital de la Timone, Marseille, France; 3La Pitié-Salpétrière, Paris, France Slide

2. (12.8) Apolipoprotein E4 domain interaction results in synaptic deficits and cognitive impairment in mice (Saturday, Nov 3 2007 2:45 PM - 3:00 PM) Abstract N. ZHONG1, G. RAMASWAMY1, K. SCEARCE-LEVIE1, *K. H. WEISGRABER1,2,3; 1Inst. Neruolog Dis., J David Gladstone Inst., San Francisco, CA; 2Dept. of Pathology, 3Cardiovasc. Res. Inst., Univ. of California, San Francisco, San Francisco, CA Slide

3. (16.9) Investigating a role for PCSK9 in the regulation of cholesterol homeostasis during synaptic remodelling (Saturday, Nov 3 2007 3:00 PM - 3:15 PM) Abstract *S. BELANGER JASMIN1, V. PEARSON1, D. DEA2, L. THÉROUX2, J. POIRIER3; 1Dept Neurol & Neurosurg, 2Douglas Mental Hlth. Univ. Inst., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Slide

4. (21.7) Possible modulation of key enzyme of clock gene StAR for circadian glucocorticoid synthesis by chronic/acute exercise-induced stress protein HSP70 in adrenal cortex (Saturday, Nov 3 2007 2:30 PM - 2:45 PM) Abstract *Y. ATOMI1,2, M. FUJITA3, H. ARAI4; 1Transdisciplinary Initiative for Global Sustainability, 2Interdisciplinary Res. Syst. for Global Sustainability Sci., The Univ. of Tokyo, Tokyo, Japan; 3Dept. Immunol., Ntl Inst. Neurosci, Ntl Ctr. Neurol and Psych, Kodaira, Japan; 4Dept. of Life Sci., The Univ. Tokyo, Tokyo, Japan Slide

5. (33.14/D18) Role of prenylation on Rac1 activation and neurite outgrowth (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract F. SAMUEL, H. MO, *D. L. HYNDS; Dept Bio, Texas Woman's Univ., Denton, TX Poster

6. (43.5/H6) Compartmentalization of neuronal GIRK channels (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *J. O. COLON, K. WICKMAN; Pharmacol., Univ. Minnesota, Minneapolis, MN Poster

7. (44.12/I4) Lipid raft/caveolae localization and trafficking regulates Gs alpha/adenylyl cyclase signaling (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *J. A. ALLEN; U.Illinois Coll Med., Chicago, IL Poster

8. (45.11/J6) Lateral diffusion of lipids at inhibitory and excitatory synapses (Poster Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract M. RENNER1, C. SCHWEIZER1, D. CHOQUET2, *A. TRILLER1; 1Lab. Cell Biol Of Synapse, Dept Biol ENS, Paris 75005, France; 2Insitut Magendie, CNRS UMR 5091, Bordeaux, France Poster

9. (52.16/O9) The role of dietary lipids in brain aging and cognitive decline (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract L. R. FREEMAN1, C. STEVENS2, V. HALEY-ZITLIN2, K. SAMBAMURTI3, V. ZAMAN3, A. B. MOORE3, C. UMPHLET3, J. L. LOCKROW3, I. SINGH4, *A.-C. E. GRANHOLM3; 1Neurosci, Med. Univ. of South Carolina, Charleston, SC; 2Food Sci. and Human Nutr., Clemson Univ., Clemson, SC; 3Neurosci, 4Pediatrics, Med. Univ. of South Carolina, Charleston, SC Poster

10. (52.28/P1) siRNA silencing of cholesterol pathway molecules in neuron-enriched hippocampal cultures and cortical astroglial cultures of rat E18 brain tissues: Implications for brain aging (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *K.-C. CHEN, C. DILLEY, M. OLSON, N. M. PORTER, P. W. LANDFIELD; Dept Pharmacol, Univ. Kentucky, Lexington, KY Poster

11. (64.7/Y2) Effects of ethanol on the content of sphingosine-1-phosphate and phosphatidic acid in the developing brain (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *M. SAITO1,3, G. CHAKRABORTY2, R. WANG2, T. B. COOPER1,4, C. VADASZ2,3, M. SAITO2,3; 1Analytical Psycopharmacol, 2Lab. of Neurogenetics, Nathan S. Kline Inst., Orangeburg, NY; 3Psychiatry, New York Univ. Med. Ctr., New York, NY; 4New York State Psychiatric Inst., New York, NY Poster

12. (94.18/UU3) Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract D. M. O. RAMIREZ, *T. KOTTI, D. W. RUSSELL; Dept Molec Genet., UT Southwestern Med. Ctr., Dallas, TX Poster

13. (115.13) Vicious cycle in Alzheimer’s disease: Amyloid beta aggravates its own production (Sunday, Nov 4 2007 11:00 AM - 11:15 AM) Abstract *G. P. ECKERT1, I. PETERS1, W. G. WOOD2, W. E. MULLER1; 1Dept Pharmacol, Univ. Frankfurt, Frankfurt, Germany; 2Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide

14. (117.2) Reduced geranylgeranylation of rho family GTPases by lovastatin preserves oligodendrocyte progenitors and promotes myelin repair in an experimental autoimmune encephalomyelitis model (Sunday, Nov 4 2007 8:15 AM - 8:30 AM) Abstract *A. S. PAINTLIA1, M. K. PAINTLIA1, I. SINGH1, A. K. SINGH2; 1Pediatrics, 2Ralph H. Johnson V. A. Med. Ctr., MUSC, Charleston, SC Slide

15. (148.1/M26) Acute extraction of cholesterol with methyl-betha-cyclodextrin induces IP3-mediated calcium transients in cultured astrocytes (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract K. JEFTINIJA, E. W. ROWE, *S. JEFTINIJA; Biomed Sci., Iowa State Univ. Col. Vet Med., Ames, IA Poster

16. (151.11/P8) The membrane association of LRRK2 is isoprenylation-dependent (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *J. M. CORDY, C. H. HSU, B. WOLOZIN; Pharmacol., Boston Univ. Sch. Med., Boston, MA Poster

17. (151.21/P18) Transcriptome analysis of laser-captured dopaminergic neurons in mice overexpressing human wildtype alpha-synuclein (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *F. MORTAZAVI1, B. MEURERS1, M. S. OH2, D. ELASHOFF2, E. MASLIAH4, M.-F. CHESSELET1,3; 1Dept Neurol, 2Publ. Hlth. Dept., 3Dept Neurobiology, UCLA, Los Angeles, CA; 4Depts of Neurosciences and Pathology, UCSD, San Diego, CA Poster

18. (152.8/Q14) Over-expression of ABCA1 in the brain increases lipidation of apoE and decreases both apoE and amyloid levels in the CNS (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *H. JIANG1,2, S. E. WAHRLE1,2, M. PARSADANIAN1,2, D. M. HOLTZMAN1,2; 1Dept. of Neurol., Washington Uni, Saint Louis, MO; 2Hope Ctr. for Neurological Disorders, Washington Univ., Saint Louis, MO Poster

19. (152.14/Q20) Synaptic amyloid-beta correlates with oligomers and colocalizes with p-tau (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *K. GYLYS1, S. SOKOLOW1, K. HENKINS2, J. FEIN1, C. A. MILLER4, H. V. VINTERS3, G. M. COLE5; 1Schl Nursing & Brain Res. Inst., 2Interdepartmental Neurosci. Program, 3Pathology and Lab. Med., UCLA, Los Angeles, CA; 4Pathology , Neurology, and Program in Neurosci., Keck USC Sch. of Med., Los Angeles, CA; 5Sch. of Med., UCLA and VAMC GRECC, Los Angeles, CA Poster

20. (152.22/Q28) Lipid-ordering effects of celecoxib and fenofibrate in cellular membranes may contribute to enhanced amyloid-beta production (Poster Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract M. GAMERDINGER, A. CLEMENT, *C. W. BEHL; Med. Schl, Instit Physiol chemist & Path Johann, 55099 Mainz, Germany Poster

21. (153.2/R5) Increased autophagic activity might not automatically induce amyloid beta protein production (Poster Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract K. MAKIOKA, *T. YAMAZAKI, S. KAKUDA, K. OKAMOTO; Dept. of Neurol., Gumma Univ. Sch. of Medicnie, Maebashi, Japan Poster

22. (153.3/R6) Microglial mediated clearance of soluble Aß occurs via pinocytic mechanisms (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *S. D. MANDREKAR, Q. JIANG, E. REED-GEAGHAN, G. E. LANDRETH; Case Western Reserve, Cleveland, OH Poster

23. (154.9/S2) Increased autophagy is observed in Niemann-Pick disease type C cells (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract S. ISHIBASHI, T. YAMAZAKI, *K. OKAMOTO; Dept Neurol, Gunma Univ. Sch. Med., Maebashi, Japan Poster

24. (154.17/S10) Cognitive impairment in APP23/ABCA1+/- mice - implications for the role of ABCA1 in Alzheimer’s Disease (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *I. M. LEFTEROV1, M. STAUFENBIEL2, R. KOLDAMOVA1; 1Enviro & Occup. Hlth., Univ. Pittsburgh, Grad. Sch. Publ. Hlth., Pittsburgh, PA; 2Novartis Inst. of BioMedical Res., CH-4002 Basel, Switzerland Poster

25. (156.2/T14) Effects of human apoE2, E3, or E4 gene-targeted replacement on behavioral and cognitive performance in young male mice (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *T. J. KORNECOOK, A. P. MCKINNEY, J.-C. DODART; CNS Pharmacol., Merck, Boston, MA Poster

26. (156.10/T22) 27-hydroxycholestrol regulates GSK-3ß and the ATP-binding cassette transporters, ABCA1 and ABCG1, in organotypic slices from adult rabbit hippocampus (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *O. GHRIBI, S. SHARMA, A. HILFER, G. FEIST, J. GEIGER; Pharmacol, Physiol & Therapeut., UND Med. Sch., Grand Forks, ND Poster

27. (157.3/U14) Effect of chronic treatment with the LXR agonist, TO901317, in a triple transgenic model of Alzheimer's disease (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *J. L. SEARCY, J. T. PHELPS, E. M. BLALOCK, A. L. S. DOWLING, K.-C. CHEN, P. W. LANDFIELD, O. THIBAULT, N. M. PORTER; Mol&Biomed Pharmacol., Univ. Kentucky, Lexington, KY Poster

28. (160.10/W17) VAMP-associated protein-A inhibits lateral diffusion of membrane proteins in the endoplasmic reticulum (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *D. C. PROSSER, D. TRAN, P.-Y. GOUGEON, C. VERLY, J. K. NGSEE; Neurosci., Univ. Ottawa, Ottawa, ON, Canada Poster

29. (168.12/CC17) Quercetin-3-glucoside protects SH-SY5Y cells against oxidative damage by inducing cholesterol and phospholipid biosynthesis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *R. SOUNDARARAJAN1, A. D. WISHART1, H. P. V. RUPASINGHE3, M. ARCELLANA-PANLILIO4, C. M. NELSON5, M. MAYNE6, G. S. ROBERTSON2; 1Dept Pharmacol, 2Psychiatry & Pharmacol., Dalhousie Univ., Halifax, NS, Canada; 3Dept. of Envrn. Sci., NS Agr. Col., Truro, NS, Canada; 4Biochem. and Mol. Biol., Univ. of Calgary, Calgary, AB, Canada; 5Family & Nutritional Sci., Univ. of Prince Edward Island, Charlottetown, PE, Canada; 6Inst. of Nutrisciences and Hlth., Natl. Res. Council Canada, Charlottetown, PE, Canada Poster

30. (198.1/ZZ10) Angiotensin II AT1 receptor blockade decreases the aldosterone synthesis and release during lipopolysaccharide-induced immune stress in the adrenal gland of the rat (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *E. SANCHEZ-LEMUS, Y. MURAKAMI, I. M. LARRAYOZ-ROLDAN, J. M. SAAVEDRA; Sect. Pharmacol, NIMH, NIH, Bethesda, MD Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

31. (211.8/III27) Neural coding of steroid mixtures: Olfactory perception in the American lobster (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *S. I. CROMARTY1, G. KASS-SIMON2; 1Dept Natural Sci., Assumption Col., Worcester, MA; 2Biol. Sci., Univ. of Rhode Island, Kingston, RI Poster

32. (107.2) Retromer-Deficient Mice Model Key Features of Alzheimer’s Disease (Sunday, Nov 4 2007 8:35 AM - 9:10 AM) Abstract K. DUFF; Pathology, Columbia Univ., New York, NY Symposium

33. (223.3) Higher mid-life cholesterol levels are associated with hypometabolism in brain regions affected by Alzheimer's and normal aging (Sunday, Nov 4 2007 1:30 PM - 1:45 PM) Abstract *E. M. REIMAN1,3,4,5, K. CHEN2,5, R. J. CASELLI6,5, D. BANDY2,5, W. LEE2,5, O. SMILOVICI2,5, C. RESCHKE2,5, G. E. ALEXANDER7,5; 2Banner Good Sam PET Ctr., 1Banner Alzheimer's Inst., Phoenix, AZ; 3Translational Genomics Res. Inst., Phoenix, AZ; 4Univ. of Arizona, Tucson, AZ; 5Arizona Alzheimer's Dis. Consortium, Phoenix, AZ; 6Mayo Clin., Scottsdale, AZ; 7Psychology, Arizona State Univ., Tempe, AZ Slide

34. (240.13/E36) Requirement for palmitoylation and raft insertion of Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKI? during cortical dendritogenesis (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *S. TAKEMOTO-KIMURA, N. AGETA-ISHIHARA, M. NONAKA, H. OKUNO, H. BITO; Dept. Neurochemistry, Univ. Tokyo Grad. Sch. of Med., Tokyo, Japan Poster

35. (252.11/K27) LRP4 may play a role in maintenance of synaptic integrity and neuronal cell survival through apoE/cholesterol (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *T. SUZUKI, Y. LU, Q.-B. TIAN; Neuroplasticity, Shinshu Univ. Grad Sch. Med., Matsumoto 390-8621, Japan Poster

36. (256.14/N24) Walnuts can improve motor and cognitive function in aged rats (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *B. SHUKITT-HALE, V. CHENG, D. F. BIELINSKI, J. A. JOSEPH; USDA, ARS, Human Nutrit Res. Ctr. On Aging, Boston, MA Poster

37. (257.4/O11) EcoG mapping and lesion verification of the origin of atypical absence epilepsy in GABAB R1a overexpression transgenic mice (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *X. WANG, M. A. CORTEZ, J. PERAZ VELAZQUEZ, C. LIU, L. SHEN, O. C. SNEAD, III; Dept Brain & Behav, Hosp. Sick Children, Toronto, ON, Canada Poster

38. (260.3/Q25) Cortical injury increases cholesterol 24s hydroxylase (cyp46) levels in the rat brain (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *C. M. CARTAGENA1, F. AHMED1, A. PAJOOHESH-GANJI1, D. T. PAK2, A. I. FADEN1, G. W. REBECK1; 1Dept Neurosci, 2Dept Pharm, Georgetown Univ., Washington, DC Poster

39. (260.4/Q26) ATP binding cassette transporter A1 (ABCA1) expression is upregulated in the mouse hippocampus following unilateral entorhinal cortex lesions (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *V. PEARSON1,2, S. BELANGER-JASMIN1,2, D. DEA1, L. THEROUX1, J. POIRIER1,2,3; 1Dept of Neurosci., Douglas Mental Hlth. Inst., Montreal, PQ, Canada; 2Dept. of Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Poster

40. (293.14/QQ5) Effect of manipulating developmental androgens and AR activation on hippocampal anatomy and hippocampal-dependent behavior performance (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *C. CHEN1, J. NUNEZ2; 1Psychology Dept., 2Psychology Department/Neurosci. Dept., Michigan State Univ., East Lansing, MI Poster

41. (309.12/DDD20) Estradiol replacement does not affect performance of ovariectomized rats on a water maze pattern completion task (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *J. BOHACEK1, N. A. HALAPIN1, J. CROSS-CALL2, J. M. DANIEL3; 1Dept Neurosci, 2Psychology, 3Psychology and Neurosci., Tulane Univ., New Orleans, LA Poster

42. (314.4/GGG24) Regulation of CNS alpha-estrogen receptor by two subcutaneous delivery systems of estradiol (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *L. MOSQUERA, L. AROCHO, A. TORRADO, Y. TORRES, J. MIRANDA, A. SEGARRA; Univ. of PR, Sch. of Med., San Juan, Puerto Rico Poster

43. (315.4/HHH4) Mass spectral analysis of recombinant vesicular glutamate transporter protein after reconstitution into liposomes (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract C.-K. CHAO1, S. A. PATEL1, *C. M. THOMPSON2; 1Biomed. and Pharmaceut. Sci., Univ. of Montana, Missoula, MT; 2Prof Med. Chem., Univ. Montana, Missoula, MT Poster

44. (331.3) An inhibitor of ceramide transport for sphingomyelin synthesis selectively increases abeta 42 secretion by SH-SY5Y overexpressing the amyloid precursor protein (Monday, Nov 5 2007 8:30 AM - 8:45 AM) Abstract *C. V. ZERBINATTI, S. SUON, M. YOUNG, G. R. SEABROOK, W. J. RAY; Dept Alzheimer's Res., Merck & Co., West Point, PA Slide

45. (331.7) Expression of cholesterol related genes is up-regulated in the Tg2576 mouse model of Alzheimer's disease (Monday, Nov 5 2007 9:30 AM - 9:45 AM) Abstract *H. K. WARWICK1, T. A. COMERY1, S. ASCHMIES1, E. KOURANOVA1, R. H. RING1, M. FOLLETTIE2, L. WANG2, A. HILL2, Y. KIRKSEY1, P. H. REINHART1, D. R. RIDDELL1; 1Discovery Neurosci., Wyeth Res., Monmouth Junction, NJ; 2Biol. Technologies, Wyeth Res., Cambridge, MA Slide

46. (350.20/F24) Peripheral benzodiazepine receptor distribution in the human brain postmortem (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *A. BIEGON1,2, K. BARON-SELA4,2, M. WEISER4,3, N. ROZ5, M. REHAVI5; 1Med. Dept, Brookhaven Natl. Lab., Upton, NY; 2J. Sagol Neurosci. Ctr., 3Psychiatry, Sheba Med. Ctr., Ramat Gan, Israel; 5Physiology&Pharmacology, 4Tel Aviv Univ., Tel Aviv, Israel Poster

47. (354.1/G50) Cholesterol stabilizes the fusion pore of chromaffin granules before rapid dilation (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract N. WANG1,2, C. KWAN2, E. POSSE DE CHAVES1,2, *A. M. TSE1,2, F. W. TSE1,2; 1Dept Pharmacol, 2Ctr. for Neurosciences, Univ. Alberta, Edmonton, AB, Canada Poster

48. (354.6/H1) Cholesterol extraction disrupts cerebellar synaptic transmission(Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *A. J. SMITH, M. P. CHARLTON; Univ. Toronto, Toronto, ON, Canada Poster

49. (366.7/P2) Lrh-1/nr5a2: mediator of tau pathology via cholesterol regulation? (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *A. R. SYLVESTER, Y. M. GOZAL, J. LAH, A. I. LEVEY; Emory Univ., DECATUR, GA Poster

50. (367.13/Q6) Tau phosphorylation in lipid rafts in response to Abeta(25-35): involvement of Cdk5 (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract *P. A. HERNANDEZ1, G. LEE2, R. B. MACCIONI1; 1Biol., Univ. of Chile, Santiago, Chile; 2Intrnl. Med., The Univ. of Iowa, Iowa City, IA Poster

51. (368.5/Q26) Age-related changes in the composition of membrane microdomains might increase the susceptibility of mature hippocampal neurons to beta-amyloid-induced calpain-mediated neurotoxicity (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract *A. M. NICHOLSON, A. FERREIRA; Cell & Mol. Biol, Northwestern Univ., Chicago, IL Poster

52. (378.11/Y8) Microemboli composed of cholesterol disrupt the blood brain barrier and reduce cognitive function (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *M. NEUMANN1, J. H. RAPP2, X. PAN2, S. HONG1, K. HOLLENBECK2, J. LIU1; 1Dept Neurosurgery, 2Dept Surgery, UCSF, VA Med. Ctr., San Francisco, CA Poster 53. (422.6/FFF28) ApoE4 affects spatial learning and memory in children (Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *S. F. ACEVEDO, J. RABER; Behav Neurosci, OHSU, Portland, OR Poster

54. (443.1) Effects of cholesterol oxidation products on exocytosis in pheochromocytoma-12 cells (Monday, Nov 5 2007 1:00 PM - 1:15 PM) Abstract *W. ONG; Dept Anat., Natl. Univ. Singapore, Singapore 119260, Singapore Slide

55. (444.4) Translational control of BACE1 in response to chronic energy deprivation (Monday, Nov 5 2007 1:45 PM - 2:00 PM) Abstract *T. L. O'CONNOR, E. MAUS, R. VASSAR; Cell & Mol. Biol, Northwestern Univ., Chicago, IL Slide

56. (448.6) Quantification and perturbation of the isoprenoids FPP and GGPP in mouse brain and primary neurons (Monday, Nov 5 2007 2:15 PM - 2:30 PM) Abstract D. A. VOLMER1, G. HOOFF2, G. P. ECKERT2, *W. G. WOOD3, W. E. MULLER2; 1HNR, Med. Res. Council, Cambridge, United Kingdom; 2Pharmacol., Univ. of Frankfurt, Frankfurt, Germany; 3Pharmacology/GRECC, Univ. Minnesota/VA Med. Ctr., Minneapolis, MN Slide

57. (458.22/D26) IL-6/sIL-6Ra chimera affects cerebral oligodendrocyte maturation and myelination in perinatal mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *S. H. BRUNSSEN1, J. GOHLKE2, A. D. TOEWS1, G. HARRY2; 1Univ. North Carolina- Chapel Hill, Chapel Hill, NC; 2NIEHS, NIH, DHHS, Research Triangle Park, NC Poster

58. (461.4/F20) Perturbation of cholesterol synthesis and trafficking affects retinal development and function (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract A. NIEMIEC, *T. CLAUDEPIERRE, K. NIEWEG, I. BUARD, F. PFRIEGER; Neurotransmission/secretion, Inst. Neurosci. Cell. Integ., Strasbourg, France Poster

59. (471.17/M4) Enrichment of cholesterol modulates ion channels via breakdown of phosphatidylinositol 4,5-bisphosphate (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract Y. CHUN1, S. SHIN1, M. PARK1, S. V. VORONOV2, T.-W. KIM2, G. DI PAOLO2, B.-C. SUH3, *S. CHUNG1; 1Dept Physiology, Sungkyunkwan Univ., Suwon, Republic of Korea; 2Dept. of Pathology, Columbia Univ. Med. Ctr., New York, NY; 3Dept. of Physiology and Biophysics, Univ. Washington Sch. of Med., Seattle, WA Poster

60. (472.4/M18) Pregnenolone sulfate increases glutamate release onto cerebellar Purkinje Cells (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *P. A. ZAMUDIO, M. CARTA, C. F. VALENZUELA; Neurosci., Univ. New Mexico, Albuquerque, NM Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

61. (474.2/N28) The effects of Statins on synaptic transmission and Aß-mediated attenuation of Long Term Potentiation (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract L. T. BREEN, A. CAMPOS-TORRES, *C. E. HERRON; Sch. Biomolecular & Biomed Sci., Univ. Coll Dublin, Dublin, Ireland Poster

62. (477.7/Q24) Sphingomyelinase suppresses hippocampal CA1 neuron excitability by inhibiting sodium currents (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract *E. D. NORMAN, R. CUTLER, M. MATTSON; Lab. Neurosci, Natl. Inst. Aging, Baltimore, MD Poster

63. (483.1/U1) High fat/high cholesterol diet-induced bace-1 expression and app processing (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *L. THIRUMANGALAKUDI1, A. PRAKASAM2, S. MOHANTY2, K. SAMBAMURTI2, N. R. BHAT2; 2Neurosciences, 1Med. Univ. South Carolina, Charleston, SC Poster

64. (483.22/U22) Synaptic changes in the outer plexiform layer of the PDAPP/APOE4 double-transgenic mouse retina (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *J.-D. DING1, B. MACE2, R. HERRMANN1, P. SULLIVAN2, C. BOWES RICKMAN1,3; 1Ophthalmology, 2Med., 3Cell Biol., Duke Univ. Med. Ctr., Durham, NC Poster Session No.483: Alzheimer's Disease: Physiological Functions of APP and APP Metabolites II

65. (485.12/W7) Omega-3 fatty acid docosahexaenoic acid upregulates sorla/lr11, a sorting protein with reduced expression in sporadic Alzheimer disease (AD): potential for AD prevention (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *Q.-L. MA1,2, B. TETER1,2, T. MORIHARA3, O. J. UBEDA1,2, F. YANG1,2, W. BEECH1,2, G. P. LIM1,2, S. FRAUTSCHY1,2,4, G. M. COLE1,2,4; 1Sepulveda VA Med. Ctr., Greater Los Angeles Vets Affairs Hlth. Sys VA Med. Cntr, North Hills, CA; 2Dept. of Medicine, UCLA, North hills, CA; 3Psychiatry, Osaka Univ., Osaka, Japan; 4Dept. of Neurology, UCLA, North hills, CA Poster

66. (485.18/W13) Role of N-glycosylation in ACAT inhibition-mediated ER-associated degradation of APP (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *C. A. PEACH, C. A. BARREN, H. J. HUTTUNEN, D. M. KOVACS; MIND, Mass Gen Hosp/Harvard Med. Sch., Charlestown, MA Poster

67. (486.9/X3) Commonly used tool lxr agonists directly modulate ?-secretase activity (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract K. ATCHISON1, H. ZHOU1, Y. KIRKSEY1, *R. L. MARTONE2, M. N. PANGALOS1, P. H. REINHART1, S. JACOBSEN1, D. R. RIDDELL1; 1Wyeth Res., Princeton, NJ; 2Dept CNS Disorders, Wyeth-Ayerst Res., Princeton, NJ Poster

68. (486.14/X8) Molecular mechanisms underlying amyloid ß modulating effects of fenofibrate(Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract C. M. LILL, B. ZHANG, A. V. THOMAS, L. HERL, A. DENG, P. JONES, A. IVANOV, *M. GARCIA ALLOZA, B. T. HYMAN, O. BEREZOVSKA; MassGenl Inst. Neurodegen Dis., Massachusetts Genl Hosp., Boston, MA Poster

69. (490.10/AA11) Genetic modifiers of Niemann-Pick type C disease in mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *D. SYMULA1, K. COLLINS2,3, M. PEARCE2; 1Wadsworth Ctr. / Univ., Albany, NY; 2Wadsworth Ctr., Albany, NY; 3Univ. at Albany, Albany, NY Poster

70. (493.8/CC15) The small Rho-GTPase Rac1 is involved in lipid raft trafficking after oxygen glucose deprivation - Implications for dopamine receptor transport in astrocytes (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *K. RUSCHER, M. RICKHAG, T. WIELOCH; Wallenberg Neurocentrum, Lab. for Exp Brain Res., Lund, Sweden Poster

71. (495.14/EE18) Steryl glycoside induced cytopathological changes in the motor neuron-derived NSC-34 cells (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *P. T. LY1,2, C. A. SHAW1,2,3; 1Exptl. Med., Univ. British Columb, Vancouver, BC, Canada; 2Ophthalmology & Visual Sci., 3Neurosci., Univ. of British Columbia, Vancouver, BC, Canada Poster

72. (519.22/XX5) Sex-dependent metabolic, neuroendocrine and cognitive responses to dietary energy restriction and excess (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *B. MARTIN1, M. PEARSON1, L. KEBEJIAN1, E. GOLDEN1, A. KESELMAN1, M. BENDER1, O. CARLSON2, J. EGAN2, B. LADENHEIM4, J. CADET4, K. BECKER3, W. WOOD3, K. DUFFY5, P. VINAYAKUMAR3, S. MAUDSLEY1,6, M. P. MATTSON1,7; 1Lab. Neurosci, Natl. Inst. Aging, Baltimore, MD; 2Lab. Clin. Investigation, 3Gene Expression and Genomics Unit, Natl. Inst. on Aging Intramural Res. Program, Baltimore, MD; 4Mol. Neuropsychiatry Br., 5Lab. Exptl. Gerontology, Natl. Inst. on Drug Abuse, Baltimore, MD; 6Harbor Hosp., MedStar Res. Inst., Baltimore, MD; 7Dept. of Neurosci., Johns Hopkins Univ. Sch. of Med., Baltimore, MD Poster

73. (547.3) Regulation of membrane lipid metabolism by gamma-secretase (Tuesday, Nov 6 2007 8:30 AM - 8:45 AM) Abstract *J. G. WALTER1, K. PRAGER1, D. R. THAL2, K. THELEN3, T. WAHLE1, I. DEWACHTER4, P. ST. GEORGE-HYSLOP5, S. S. SISODIA6, D. LÜTJOHANN3, F. VAN LEUVEN4, I. Y. TAMBOLI1; 1Neurol , Mol. Cell Biol, 2Neuropathology, Univ. Bonn, Bonn, Germany; 3Clin. Pharmacol., Univ. of Bonn, Bonn, Germany; 4Human Genet., KU Leuven, Leuven, Belgium; 5Neurol., Univ. of Toronto, Toronto, ON, Canada; 6Neurobiology, Univ. of Chicago, Chicago, IL Slide

74. (547.6) Cholesterol and isoprenoids regulate amyloid production by different mechanisms (Tuesday, Nov 6 2007 9:15 AM - 9:30 AM) Abstract *K. SAMBAMURTI1, S. ANITHA2, C. VENUGOPAL1, A. PRAKASAM1,3, S. PAUL3, S. LIN3, Y. SU3, B. LIN3, Y. ZHOU4; 1Neurosciences, MUSC, Charleston, SC; 2Cancer Ctr., NJMS-UH, Newark, NJ; 3Eli Lilly and Co., Indianapolis, IN; 4Indiana University, Sch. of Med., Charleston, IN Slide

75. (550.9) Simvastatin upregulation of endothelin-1 increases Bcl-2 mRNA/protein levels and neuroprotection in neurons (Tuesday, Nov 6 2007 10:00 AM - 10:15 AM) Abstract *T. A. BUTTERICK1, L. N. JOHNSON-ANUNA2, G. P. ECKERT3, U. IGBAVBOA4, W. E. MULLER3, W. G. WOOD4; 1Pharmacol., Univ. of Minnesota, Minneapolis, MN; 2Tufts Univ., Boston, MA; 3Pharmacol., Univ. of Frankfurt, Frankfurt, Germany; 4Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide

76. (563.11/D7) Differentiation of human SH-SY5Y neuroblastoma cells cultured on microelectrode array plates (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract H. TEPPOLA1, J.-R. SARKANEN2, J. SELINUMMI1, A. PETTINEN1, *T. O. JALONEN3, M.-L. LINNE1; 1Inst. of Signal Processing, Tampere Univ. of Technol., Tampere, Finland; 2Fac. of Med., Univ. of Tampere, Tampere, Finland; 3Biol & Envrn. Sci. Nanosci Ctr., Univ. of Jyväskylä, Jyväskylä, Finland Poster

77. (570.11/G43) Lipid rafts and cell adhesion molecules in synapse formation (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *J. R. CONSTABLE, J. GIANG, P. E. WASHBOURNE; Inst. of Neurosci., Univ. of Oregon, Eugene, OR Poster

78. (571.3/G53) Role of lipid rafts in glia-induced synapse development (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *R. THIEBAUT1, F. W. PFRIEGER2; 1UMR 7168/LC2 CNRS ULP, 2Umr 7168/lc2 cnrs ulp, CNRS, Strasbourg, France Poster

79. (571.4/G54) Proteins secreted by astrocytes enhance inhibitory axon outgrowth, branching and synaptogenesis (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *E. G. HUGHES1, S. B. ELMARIAH1, H. ISCHIROPOLOUS2,3, R. J. BALICE-GORDON1; 1Dept Neurosci, 2Dept of Pediatrics and Pharmacol., Univ. Pennsylvania, Philadelphia, PA; 3Children’s Hosp. of Pennsylvania, Philadelphia, PA Poster

80. (572.2/H24) Activation of adenosine A2A receptors increases TrkB receptors translocation to lipid rafts (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *N. ASSAIFE-LOPES1, D. B. PEREIRA2, J. A. RIBEIRO1, M. V. CHAO2, A. M. SEBASTIAO1; 1Inst. of Pharmacol and Neurosci, U. Lisbon,Fac. of Med. and IMM, Lisbon, Portugal; 2Lab. of Mol. Neurobiology, Skirball Inst. of Mol. Medicine, New York Univ., New York, NY Poster

81. (580.5/N8) Properties of synaptic transmission in Niemann-Pick type C1-deficient hippocampal neurons (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *C. R. WASSER1, E. T. KAVALALI1,2; 1Dept. of Neurosci., 2Dept. of Physiology, UT Southwestern Med. Ctr., Dallas, TX Poster

82. (588.2/S17) Molecular manipulation of hippocampal astrocytes and effect on excitatory synapses (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *E. V. JONES, K. K. MURAI; McGill Univ., Montreal, PQ, Canada Poster

83. (588.10/S25) Dendritogenesis and formation of excitatory synaptic input to Purkinje cells require glia, but not Npc1 (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract C. C. STEINMETZ, I. BUARD, *F. W. PFRIEGER; Neurotransmission/-secretion, Inst. Cell Integ Neurosci, Strasbourg Cedex, France Poster

84. (588.13/T2) Astrocyte-directed expression of wild type npc1 attenuates neuronal cholesterol storage and extends survival in npc1-/- mice(Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *M. ZHANG1, R. P. ERICKSON2, I. VINCENT3, J. L. HALLOWS4; 1Dept Neurol., Tongji Hosp., Wuhan, China; 2Dept. of Pediatrics, Univ. of Arizona, Tucson, AZ; 3Pediatrics, Univerisity of British Columbia, Vancouver, BC, Canada; 4Pediatrics, Univ. of British Columbia, Vancouver, BC, Canada Poster588. Glial-Neuronal Interactions: Regulation of Synapse Activity

85. (592.3/V11) The LXR agonist TO-901317 increases HMG-CoA reductase activity in vivo and in vitro (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *M. P. BURNS1, G. W. REBECK1, G. P. ECKERT2; 1Dept. of Neurosci., Georgetown Univ., Washington, DC; 2Dept. of Pharmacol., Univ. of Frankfurt, Frankfurt, Germany Poster

86. (592.16/V24) Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from cultured neurons (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract H. MINAGAWA1, A. WATANABE2, J.-S. GONG1, K. ZOU1, T. NAKAMURA1, S. LUND-KATZ3, M. C. PHILLIPS3, H. SAITO4, *M. MICHIKAWA1; 1Dept Alzheimer's Dis. Res., 2Dept Vascular Dementia Res., Natl. Centr Geriatrics Gerontol, Obu-shi, Japan; 3Children's Hosp. of Philadelphia, Univ. of Pennsylvania Sch. of Med., Philadelphia, PA; 4Dept. of Biophysical Chemistry, Kobe Pharmaceut. Univ., Kobe, Japan Poster

87. (600.19/BB15) Simvastatin, not atorvastatin, reduces macrophage invasion and astrogliosis after traumatic spinal cord injury (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *C. M. MANN1, Y. XIE1, J. H. LEE1, A. T. STAMMERS1, H. M. SOHN1, J. LIU1, D. SUTHERLAND1, C. K. LAM1, W. TETZLAFF1, B. K. KWON1,2; 1ICORD, 2Dept. of Orthopaedics, Univ. of British Columbia, Vancouver, BC, Canada Poster

88. (609.11/II24) The effects of ethanol on cholesterol transport proteins in adrenal and brain (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *K. N. BOYD1, T. D. IRONS2, S. KUMAR3, A. L. MORROW4; 1Toxicology, 2IBMS, 3Psychiatry, 4Psychiatry and Pharmacol., Univ. North Carolina, Chapel Hill, NC Poster

89. (625.3/UU21) Estrogen differentially affects leu-enkephalin and dynorphin immunoreactivity in the dorsal hippocampus of young, mature and old female rats (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *T. J. WILLIAMS1,2, A. TORRES-REVERON1, A. C. GORE3, B. MCEWEN4, T. A. MILNER1,4; 1Neurol and Neurosci, Weill Cornell Med. Coll, New York, NY; 2Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program, New York, NY; 3Div. of Pharmacol. and Toxicology, Univ. of Texas at Austin, Austin, TX; 4Harold and Margaret Milliken Hatch Lab. of Neuroendocrinology, The Rockefeller Univ., New York, NY Poster

90. (638.23/FFF15) Effects of cranial Cesium irradiation on neuronal markers in human apoE transgenic female mice (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *L. E. VILLASANA1, C. POAGE1, T. PFANKUCH1, J. RABER1,2,3; 1Behav Neurosci, Oregon Hlth. & Sci. Univ., Portland, OR; 2Neurol., 3Div. of Neuroscience, ONPRC, OHSU, Portland, OR Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

91. (658.7) Novel in vivo and mechanistic insights on the role ACAT inhibition in Aß generation (Tuesday, Nov 6 2007 2:30 PM - 2:45 PM) Abstract *H. J. HUTTUNEN1, B. HUTTER-PAIER2, C. A. PEACH1, C. A. BARREN1, M. WINDISCH2, D. M. KOVACS1; 1MIND, Mass Gen. Hosp/Harvard Med., Charlestown, MA; 2JSW Res., Graz, Austria Slide Session No. 658. Alzheimer's Disease: Anti-Abeta Therapies

92. (659.7) Cholesterol lowering agents reduce accumulation of alpha-synuclein in models of Parkinson's Disease (Tuesday, Nov 6 2007 2:30 PM - 2:45 PM) Abstract *A. O. KOOB1, P. BAR-ON1, E. ROCKENSTEIN1, L. CREWS2, A. ADAME1, E. MASLIAH1,2; 1Neurosciences, 2Pathology, UCSD, San Diego, CA Slide

93. (676.20/E37) Geranylgeranyl pyrophosphate is required for calcium-dependent catecholamine secretion(Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *E. TACHIKAWA1, H. TAIRA3, M. M. HOSSAIN4, Y. YOSHIOKA2, K. MIZUMA1, Y. KONDO1, S. GOTO1, Y. IRIE1, E. TAIRA1, H. NAKAGAWA5; 1Dept Pharmacol., 2High Field MRI Res. Insti, Advanced Med. Sci. Res. Cent, Iwate Med. Univ., Morioka, Japan; 3Fac. of Agr., Iwate Univ., Morioka, Japan; 4Cent Environ Hlth. Sci, Dept Basic Sci., Miss State Univ., Jackson, MS; 5Dept. of Life Sci., Univ. of Tokushima, Tokushima, Japan Poster

94. (689.15/K27) A low-density lipoprotein receptor isoform lacking exon 4 is present in low-density lipoprotein receptor knock-out mouse brain (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *J. F. ABISAMBRA1,2, J. PADMANABHAN1,2, I. WEFES2, P. NEAME1, H. POTTER1,2; 1Johnnie B. Byrd, Sr. Alzheimer's Ctr. & Res. Inst., Tampa, FL; 2Univ. of South Florida, Tampa, FL Poster

95. (690.3/L13) Dhcr7 downregulation results in complex transcriptome changes in Neuro2a cells (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *Z. KORADE1, A. KENWORTHY2, K. MIRNICS3; 1Dept. of Biochem., 2Dept. of Mol. Physiology and Biophysics, 3Dept. of Psychiatry, Vanderbilt Univ., Nashville, TN Poster

96. (690.7/L17) Direct regulation of gamma-secretase by its lipid microenvironment (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *P. OSENKOWSKI, W. YE, L. MORRIS-SMITH, M. S. WOLFE, D. J. SELKOE; Cntr for Neurologic Dis., Harvard Med. Sch., Boston, MA Poster Session No. 690. Alzheimer's Disease: Presenilin Function II

97. (701.7/T24) Potential role of apolipoprotein-E in clearance of apoptotic bodies (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *D. A. ELLIOTT, W. S. KIM, B. GARNER; POWMRI, Randwick, Australia Poster

98. (725.17/MM18) Role of steroid receptor-mediated mechanisms at the level of the amygdala in the regulation of anxiety and visceral pain (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *B. MYERS, B. GREENWOOD-VAN MEERVELD; Univ. Oklahoma HSC, Oklahoma City, OK Poster

99. (732.1/RR3) 17ß-estradiol and cholesterol silastic implants prevent chronic stress-induced hippocampal CA3 dendritic retraction in ovariectomized female rats (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *K. J. MCLAUGHLIN, J. S. HARMAN, R. HAJO, J. GOMEZ, C. D. CONRAD; Psych, Behavioral Neurosci, Arizona State Univ., Tempe, AZ Poster

100. (743.2/AAA25) Memory impairment occurred in mice deficient for lipoprotein lipase is probably caused by decrease of pre-synaptic vesicles (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *D. CHUI1, T.-T. LIU1, X. XIAN2, J. YU1, Y. MIAO1, Y. YU1, G. LIU2; 1NeuroScience Resch Inst., Peking Univ., Beijing, China; 2Inst. of Cardiovascular, Peking Univ., Beijing, China Poster Session No. 743: Cognitive Learning and Memory Systems VII

101. (763.12) A rabbit eyeblink conditioning model for Alzheimer's disease treatment research (Wednesday, Nov 7 2007 10:45 AM - 11:00 AM) Abstract *C. J. MCKINNEY1,2, M. T. ALLEN2; 1Applied Stats & Rsch Mtds, Univ. Northern Colorado, Greeley, CO; 2Sch. of Psychological Sci., Univ. of Northern Colorado, Greeley, CO Slide Session No.763: Alzheimer's Disease and Other Dementias: Experimental Models II

102. (763.13) Hypercholesterolemia-induced alteration in insulin signaling: Implications in a model for sporadic Alzheimer’s Disease (Wednesday, Nov 7 2007 11:00 AM - 11:15 AM) Abstract *S. SHARMA, G. FEIST, B. SIEFKEN, O. GHRIBI; Dept Physiol Pharmacol & Therap, Univ. North Dakota Sch. Med., Grand Forks, ND Slide Session No. 763: Alzheimer's Disease and Other Dementias: Experimental Models II

103. (785.5/G38) Effects of membrane cholesterol disruption on IP3-mediated calcium liberation (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *S. M. WILTGEN, I. F. SMITH, I. PARKER; Neurobiology and Behavior, Univ. California, Irvine, Irvine, CA Poster

104. (795.9/N1) Changes in the expression of genes involved in cholesterol trafficking with the progression of Alzheimer’s disease (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *A. AKRAM1, P. KATSEL1, P. HOF2, V. HAROUTUNIAN1; 1Psychiatry, 2Neurosci., Mount Sinai Sch. of Med., New York, NY Poster Session No.795: Alzheimer's Disease and Other Dementias: Genetics and Functional Genomics

105. (795.17/N9) The association of cholesterol levels and APOE promoter polymorphism with vascular dementia (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *F. LIU1, W.-D. XU2, C. JIA2, J. LI3; 1Dept Neurol., Fengtian Hosp Shenyang Med. Col., Shenyang, China; 2Fengtian Hosp. of Shenyang Med. Col., Shenyang, China; 3China Med. Univ., Shenyang, China Poster

106. (800.19/R16) Apolipoprotein E-mimetic peptides promote the survival and proliferation of oligodendrocyte precursor cells in vitro and remyelination in vivo (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract *F.-Q. LI1,2, J. E. NEIL2, C. A. COLTON1, M. P. VITEK1,2; 1Dept Med., Duke Univ. Med. Ctr., Durham, NC; 2Cognosci, Inc., Research Triangle Park, NC Poster

107. (807.22/X21) Cerebellar lipids in mice with Rett Syndrome (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract K. A. HEINECKE, J. G. MANTIS, *T. N. SEYFRIED; Dept Biol, Boston Col., Chestnut Hill, MA Poster

108. (823.4/HH2) Enhanced expression of peripheral-type benzodiazepine receptor induces neuropathic pain (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *T. TANABE, D. KONDO, R. YABE, I. TAKASAKI, T. KURIHARA, H. SAEGUSA, S. ZONG; Dept Pharmacol/Neurobiol, Tokyo Med. & Dent. Univ. Grad Sch. Med., Tokyo, Japan Poster

109. (856.12) Amyloid beta-protein stimulates retrograde transport of cholesterol and caveolin from the plasma membrane to the Golgi complex in mouse primary astrocytes (Wednesday, Nov 7 2007 3:45 PM - 4:00 PM) Abstract *U. F. IGBAVBOA1, W. G. WOOD2; 1Dept of Pharmacol, Univ. of MN- VA Med. Ctr., Minneapolis, MN; 2Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide Session No. 856. Abeta Toxicity

110. (857.5) Expression of ABC transporters in the human brain and their impact on cholesterol efflux and amyloid-beta processing (Wednesday, Nov 7 2007 2:00 PM - 2:15 PM) Abstract *W. S. KIM1, S. L. CHAN1, A. F. HILL2, B. GARNER1; 1Prince of Wales Med. Res. Inst., Sydney, Australia; 2Dept. of Biochem. and Mol. Biol., Univ. of Melbourne, Melbourne, Australia Slide Session No. 857: Abeta Degradation and Clearance

111. (878.13/G33) GPR50: an orphan G protein-coupled receptor implicated in psychiatric illness and cholesterol metabolism (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *P. A. THOMSON1, H. L. KINNELL2, E. GRÜNEWALD2, D. H. R. BLACKWOOD2,3, D. J. PORTEOUS2; 1Univ. of Edinburgh, Edinburgh, ; 2Univ. of Edinburgh, Edinburgh, United Kingdom; 3Royal Edinburgh Hosp., Edinburgh, United Kingdom Poster Session No. 878: G-Protein Coupled Receptors: Other

112. (880.4/H13) Modulation of dopamine transporter cellular localization and protein conformation by membrane cholesterol (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *W. HONG, S. G. AMARA; Dept Neurobiol, Univ. Pittsburgh, Pittsburgh, PA Poster Session No.880. Transporters: Dopamine II

113. (880.5/H14) Membrane raft association and posttranslational fatty acid modification of the dopamine transporter (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *J. D. FOSTER, S. D. ADKINS, R. A. VAUGHAN; Biochem & Molec Biol, Univ. N Dakota Sch. Med. & Hlth. S, Grand Forks, ND Poster

114. (880.6/H15) AMPH and METH partition hDAT into different plasma membrane microdomains (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *H. KHOSHBOUEI1, N. SEN3, J. A. JAVITCH3, J. S. GOODWIN2; 1Dept Biol. Sci., 2Dept Biomed. Sci., Meharry Med. Coll, Nashville, TN; 3Departments of Psychiatry and Pharmacol., Ctr. for Mol. Recognition, Columbia University College of Physicians and Surg, NY Poster

115. (884.6/K4) Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *G. BU, Q. LIU; Washington Univ., St. Louis, MO Poster Session No.884: Alzheimer's Disease: Physiological Functions of APP and APP Metabolites III NoL related items: 1 | 2

116. (885.5/K26) Domains in LRP cytoplasmic tail in Aß generation and trafficking of APP to lipid rafts (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *E. C. CHEN, M. K. LAKSHMANA, I. YOON, E. H. KOO, D. E. KANG; Dept. Neurosciences, UCSD, La Jolla, CA Poster Session No.885: Alzheimer's Disease: APP Processing

117. (885.9/L2) Monitoring Amyloid Precursor Protein (APP) and Beta-Secretase interaction in living cells by Total internal reflection energy transfer (TIRET) microscopy (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *C. A. VON ARNIM1, B. VON EINEM1, D. SCHWANZAR1, M. WAGNER2, P. WEBER2, H. SCHNECKENBURGER2; 1Dept Neurol, Univ. Ulm, 89075 Ulm, Germany; 2Inst. für Angew. Forschung, Hochschule Aalen, Aalen, Germany Poster Session No.885: Alzheimer's Disease: APP Processing <>

118. (886.7/L23) Downstream effects of statins on amyloid precursor protein processing and Aß secretion (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract N. POZDNYAKOV, C. E. OBORSKI, B. A. MARTIN, M. A. COLLINS, J. E. FINLEY, K. L. TODD, R. B. NELSON, D. R. LISTON, H. J. HARWOOD, B. TATE, *L.-F. LAU; CNS Discovery, Pfizer Global Res. & Dev, Groton, CT Poster Session No.886: Alzheimer's Disease: Anti-Abeta Treatments II

119. (890.13/P13) A consecutive analysis of biochemical markers associated with Alzheimer's disease (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *S. CULLEN1, P. CARMONEY2; 1Walden Univ., Parker, CO; 2Walden Univ., Minneapolis, MN Poster

120. (893.13/R22) Inhibition of activity of plasma membrane ganglioside sialidase (PMGS) and disruption of lipid rafts attenuates ability of axons to regenerate (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract S. KAPPAGANTULA, *J. W. FAWCETT; Ctr. Brain Repair, Cambridge Univ., Cambridge, United Kingdom Poster Session No.893: Parkinson's Disease: Circuits

121. (896.8/T24) Altered levels of endosomal-lysosmal markers in NPC knock-out mouse brains (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *A. AMRITRAJ1, K. PEAKE2, A. KODAM1, J. E. VANCE2, S. KAR3; 1Dept of Psychiatry, 2Dept of Med., 3Dept of Psychiatry and Dept of Med., Univ. Of Alberta, Edmonton, AB, Canada Poster

122. (896.14/U2) Intraventricular infusion of recombinant human acid sphingomyelinase as a potential treatment for Niemann-Pick A disease (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract J. CLARKE, C. TRELEAVEN, T. TAKSIR, D. GRIFFITHS, W. YANG, J. BU, S. CHENG, *L. S. SHIHABUDDIN, J. DODGE; Dept Neurosci., Genzyme Corp, Framingham, MA Poster

123. (897.6/U10) Anti-inflammatory agents as theraptic potential in Niemann Pick type C disease (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract W. GONG, P. HOANG, *S. H. MELLON; Ob/Gyn, Univ. California San Francisco, San Francisco, CA Poster Session No.897: Neurodegenerative Disorders: Oxidative Stress and Inflammation

124. (900.10/X10) Paraoxonase gene polymorphisms and lipid profile in Korean ischemic stroke patients (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *B. SHIN1,3, Y. KIM3, S. OH4, S. JEONG4, K. KIM2; 1Neurol., 2Pharmacol., Chonbuk Natl. Univ., Jeonju, Republic of Korea; 3Chonbuk Natl. Univ. Hosp. Res. Inst. of Clin. Med., Jeonju, Republic of Korea; 4Chonbuk Natl. Univ. Hosp., Jeonju, Republic of Korea Poster

125. (902.3/Y28) Atorvastatin prevent apoptosis after a thoracic spinal cord contusion injury and promotes locomotion recovery (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *E. BEAUMONT1, G. ROUSSEAU2, M. BENDERDOUR2; 1Surgery, 2Pharmacol., Univ. of Montreal, Montreal, PQ, Canada Poster Session No.902: Spinal Therapeutic Strategy

126. (932.15/WW10) Effect of the ABCG1 cholesterol transporter on cognition and Alzheimer Disease (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *P. F. PARKINSON, B. L. BURGESS, T. S. KANNANGARA, B. R. CHRISTIE, C. L. WELLINGTON; UBC, Vancouver, BC, Canada Poster Session No.932: Cognitive Learning and Memory Systems IX

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

'Phospholipid' abstracts 1>30 | 31>50 | <CTRL><F> to search through this document

1. (43.3/H4) Oxidative downmodulation of Kv1.4- and Kv4.2-mediated K+-currents by arachidonic acid in transfected HEK 293 cells (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *P. R. ANGELOVA1, W. S. MUELLER2; 1Neurophysiol, Charite Med. Sch., Berlin, Germany; 2Neurosurgery, Univ. of New Mexico Med. Sch., Albuquerque, NM Poster

2. (61.16/W8) PRKCB1 and autism: reduced gene expression in the temporal cortex of autistic brains, and significant association between PRKCB1 gene variants and autistic disorder (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *A. M. PERSICO1,2, C. LINTAS1,2, R. SACCO1,2, L. GAITA1,2, R. D'ORONZIO1,2, K. GARBETT3, K. MIRNICS3,4, R. MILITERNI5, C. BRAVACCIO6, P. CURATOLO7, B. MANZI7, C. SCHNEIDER8, R. MELMED9, M. ELIA10; 1Lab. Mol Psychiat & Neurogen, Univ. Campus Bio-Medico, Rome, Italy; 2IRCCS "Fondazione S.Lucia", Rome, Italy; 3Dept. of Psychiatry, Vanderbilt Univ., Nashville, TN; 4Kennedy Ctr. for Res. on Human Develop. at Vanderbilt Univ., Nashville, TN; 5Child Neuropsychiatry, II Univ. of Naples, Naples, Italy; 6Child Neuropsychiatry, Univ. “Federico II”, Naples, Italy; 7Child Neuropsychiatry, Univ. “Tor Vergata”, Rome, Italy; 8Ctr. for Autism Res. and Educ., Phoneix, AZ; 9Southwest Autism Res. and Resource Ctr., Phoenix, AZ; 10IRCCS “Oasi Maria Santissima”, Troina (EN), Italy Poster

3. (150.1/O5) Membranes shift a-synuclein from a closed to open conformation (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *K. NAKAMURA1, V. NEMANI2, R. L. NUSSBAUM3, R. H. EDWARDS2; 1Neurol., 2Neurol. and Physiology, 3Med., UCSF, San Francisco, CA Poster

4. (152.8/Q14) Over-expression of ABCA1 in the brain increases lipidation of apoE and decreases both apoE and amyloid levels in the CNS (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *H. JIANG1,2, S. E. WAHRLE1,2, M. PARSADANIAN1,2, D. M. HOLTZMAN1,2; 1Dept. of Neurol., Washington Uni, Saint Louis, MO; 2Hope Ctr. for Neurological Disorders, Washington Univ., Saint Louis, MO Poster

5. (156.8/T20) Cognitive impairment and brain phospholipids in a rat model of dietary homocysteinemia: relation to folate and methionine (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract N. A. CRIVELLO1, B. M. ALBUQUERQUE2, K. E. D'ANCI1, W.-H. CHAO3, S. L. CASSEUS1, B. SHUKITT-HALE4, J. SELHUB5, I. H. ROSENBERG2, *A. M. TROEN6; 1Nutr. & Neurocognition Lab., 3Vitamin Metabolism and Aging Lab., 4Neurosci. Lab., 5Vitamin Metabolism and Aging Lab., 2USDA Human Nutr. Res. Ctr. Aging at Tufts Univ., Boston, MA; 6Nutr. & Neurocognition Lab., USDA Human Nutr. Res. Ctr. Aging, Boston, MA Poster

6. (168.12/CC17) Quercetin-3-glucoside protects SH-SY5Y cells against oxidative damage by inducing cholesterol and phospholipid biosynthesis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *R. SOUNDARARAJAN1, A. D. WISHART1, H. P. V. RUPASINGHE3, M. ARCELLANA-PANLILIO4, C. M. NELSON5, M. MAYNE6, G. S. ROBERTSON2; 1Dept Pharmacol, 2Psychiatry & Pharmacol., Dalhousie Univ., Halifax, NS, Canada; 3Dept. of Envrn. Sci., NS Agr. Col., Truro, NS, Canada; 4Biochem. and Mol. Biol., Univ. of Calgary, Calgary, AB, Canada; 5Family & Nutritional Sci., Univ. of Prince Edward Island, Charlottetown, PE, Canada; 6Inst. of Nutrisciences and Hlth., Natl. Res. Council Canada, Charlottetown, PE, Canada Poster

7. (260.4/Q26) ATP binding cassette transporter A1 (ABCA1) expression is upregulated in the mouse hippocampus following unilateral entorhinal cortex lesions (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *V. PEARSON1,2, S. BELANGER-JASMIN1,2, D. DEA1, L. THEROUX1, J. POIRIER1,2,3; 1Dept of Neurosci., Douglas Mental Hlth. Inst., Montreal, PQ, Canada; 2Dept. of Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Poster

8. (260.16/R10) Cyclooxygenase-2 deficient mice have improved histopathological outcomes following controlled cortical contusion injury (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *M. L. KELSO1,2, C. D. LOFTIN1, S. W. SCHEFF3,2, J. R. PAULY1,2; 1Pharmaceut. Sci., 2Spinal Cord and Brain Injury Res. Ctr., 3Sanders-Brown Ctr. on Aging, Univ. Kentucky, Lexington, KY Poster

9. (284.15/JJ5) Characterization of a metabolic pathway between arachidonoyl lysophosphatidic acid (LPA) and the endogenous cannabinoid 2-arachidonoyl glycerol (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *S. RABOUNE, H. BRADSHAW, J. WALKER; Indiana Univ., Bloomington, IN Poster

10. (352.11/G16) The signaling of OX1/hypocretin-1 receptors to phospholipase C (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *L. JOHANSSON1, M. E. EKHOLM1, J. P. KUKKONEN1,2,3; 1Neurosci., Uppsala Univ., Uppsala, Sweden; 2Biol., Åbo Akademi Univ., Turku, Finland; 3Basic Vet. Sci., Univ. of Helsinki, Helsinki, Finland Poster

11. (354.9/H4) Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract B. E. PADDOCK, *N. E. REIST; MCIN, Biomed. Sci., Colorado State Univ., Fort Collins, CO Poster

12. (355.16/H35) The lipid flippase ATP8B1 is required for neurtransmitter release at larval neuromuscular junctions of Drosophila (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *M. IMAD1, K. NAGATOMO2, K. E. ZINSMAIER1; 1ARL, Div. of Neurobiology, 2Program in Mol. and Cell. Biol., Univ. of Arizona, Tucson, AZ Poster

13. (364.20/N19) Phosphatidylserine functionalization targets single-walled carbon nanotubes to microglial cells (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *V. E. KAGAN1, W. FENG2, Y. TYURINA2, H. BAYIR2, A. SHVEDOVA3; 1Ctr. Free Radical Antiox Hlth., Univ. Pittsburgh, Pittsburgh, PA; 2Univ. of Pittsburgh, Pittsburgh, PA; 3Pathology/Physiology Res. Branch, HELD, NIOSH, Morgantown, WV Poster

14. (370.4/S4) Impact of phosphorylation of alpha-synuclein at Serine 129 on nigral neurodegeneration, alpha-synuclein localization and aggregation in rat SN (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract S. AZEREDO DA SILVEIRA, *V. PADRUN, P. AEBISCHER; Brain Mind Inst., École Polytechnique Fédérale Lausanne, Lausanne, Switzerland Poster

15. (379.15/Z4) Effect of acetyl-L-carnitine (ALCAR) on infarct size in different models of experimental focal cerebral ischemia in rats (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract F. Y. JALAL, *T. J. MAHER; Dept Pharmaceut. Sci., Massachusetts Col. Pharm., Boston, MA Poster

16. (380.11/Z23) LAU-0901, a novel platelet-activating factor antagonist, improves neurological outcome after stroke in rats (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *L. S. BELAYEV, L. KHOUTOROVA, V. L. MARCHESELLI, W. C. GORDON, N. G. BAZAN; Neurosci. Ctr., LSUHSC, New Orleans, LA Poster

17. (449.9) Novel protective mechanisms of acetyl-l-carnitine against alcohol-induced neurodegeneration (Monday, Nov 5 2007 3:00 PM - 3:15 PM) Abstract J. HAORAH1, *Y. PERSIDSKY2; 1Pharmacol. and Exptl. Neurosci., 2Dept Pathol and Microbiol, Univ. Nebraska Med. Ctr., Omaha, NE Slide

18. (455.6/A6) Involvement of beta isoform of protein kinase C in the PACAP-induced differentiation of neural stem cells into astrocytes (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract J. WATANABE1,2, T. NAKAMACHI1, D. HAYASHI1, M. NAKAMURA2, *S. NAKAJO3,1, S. SHIODA1; 1Dept. of Anatomy, Sch. of Med., Showa Univ., Tokyo, Japan; 2Dept. of Biology, Fac. of Educ. and Integrated Arts and Sci., Waseda Univ., Tokyo, Japan; 3Lab. of Biochem., Yokohama Col. of Pharm., Kanagawa, Japan Poster

19. (459.21/E23) Lysophosphatidic acid as a novel mediator of neuron-astrocyte interactions (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *T. SPOHR1, S. K. REHEN1, J. CHUN2, F. C. A. GOMES1; 1Dept Anat, Fed Univ. Rio de Janeiro, Rio de Janeiro, Brazil; 2The Scripps Res. Inst., La Jolla, CA Poster

20. (486.7/X1) Effects of phosphoinisitides on gamma-secretase activity in detergent soluble/insoluble states (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract S. OSAWA1, *S. FUNAMOTO3,1, S. YAGISHITA2, Y. IHARA3,1; 1Neuropathology, 2Life science, Univ. Tokyo, Tokyo, Japan; 3Doshisha Univ., Kizugawa, Japan Poster

21. (549.11) Early activation of protein kinase c delta following cerebral ischemia leads to release of cytochrome c from mitochondria (Tuesday, Nov 6 2007 10:30 AM - 10:45 AM) Abstract *K. DAVE, I. SAUL, M. A. PEREZ-PINZON; Dept Neurol D4-5, Univ. Miami Sch. Med., Miami, FL Slide

22. (551.12) Is microglial apoptosis an early pathogenic change in cerebral X-ALD? (Tuesday, Nov 6 2007 10:45 AM - 11:00 AM) Abstract *F. EICHLER1, J.-Q. REN2, S. NAGPAL3, M. COSSOY5, A. M. RIETSCH5, M. FROSCH4, R. M. RANSOHOFF5; 2Radiology, 3Neurol., 4Pathology, 1Massachusetts Genl Hosp., Boston, MA; 5Neurol., Cleveland Clin., Cleveland, OH Slide

23. (576.14/K24) Regulation of NMDAR channels by Phoshatidylinositol(4,5)-bisphosphate in cortical neurons (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *M. MANDAL1, Z. YAN2; 1Univ. Buffalo, Buffalo, NY; 2Physiology and Biophysics, State Univ. of New York at Buffalo, Buffalo, NY Poster

24. (600.18/BB14) The effects of acute administration of omega-3 phosphatidylcholine (PC) after spinal cord injury (SCI) in rats (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *S. TIAN1, N. A. STEPHENS1, J. LARSON-GONZALES1, R. J. GRILL2, L. M. LICHTENBERGER1; 1Integrative Biol & Pharmacol, 2Neurosurgery, Univ. Texas Med. Sch, Houston, Houston, TX Poster

25. (600.20/BB16) Differential roles for phospholipase A2family members after spinal cord injury (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *R. LOPEZ-VALES1, N. GHASEMLOU1, B. J. KERR1, E. BARBAYANNI2, K. BASKAKIS2, K. I. RATHORE1, V. CONSTANTINOU-KOKOTOU3, D. STEPHENS4, E. DENNIS4, T. SHIMIZU5, G. KOKOTOS2, S. DAVID1; 1Neurol., Ctr. for Res. in Neuroscience, McGill Univ., Montreal, PQ, Canada; 2Dept. of Chem., Univ. of Athens, Athens, Greece; 3Agr. Univ. of Athens, Athen, Greece; 4Dept. of Chem. & Biochemistry, Sch. of Medicine,, Univ. of California, San Diego, La Jolla, La Jolla, CA; 5Dept. of Biochem. and Mol. Biology, Fac. of Med., Univ. of Tokyo, Tokyo, Japan Poster

26. (608.20/II5) Evidence for altered thalamic neuronal integrity in males with familial major depressive disorder (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *R. F. DEICKEN, A. JAKARY, M. PEGUES; Dept Psychiatry, Univ. California, San Francisco/VAMC, San Francisco, CA Poster

27. (690.7/L17) Direct regulation of gamma-secretase by its lipid microenvironment (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *P. OSENKOWSKI, W. YE, L. MORRIS-SMITH, M. S. WOLFE, D. J. SELKOE; Cntr for Neurologic Dis., Harvard Med. Sch., Boston, MA Poster Session No. 690. Alzheimer's Disease: Presenilin Function II

28. (700.1/S21) Identification of specific phospholipids targeted by oxidants during neuronal cell death: Roles of Ca2+-independent phospholipase A2 (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *B. S. CUMMINGS, B. PETERSON; Pharmaceut & Biomed Sci., Univ. Georgia, Athens, GA Poster

29. (704.21/X3) Lipid profiling of U87 glioblastoma multiforme cells treated with chemotherapy and wild type p53 (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *M. R. EMMETT1, H. HE1, C. L. NILSSON1, A. G. MARSHALL1, Y. LI2, C. A. CONRAD2; 1FT-ICR MS, Natl. High Magnetic Field Lab., Tallahassee, FL; 2Neuro-oncology, M.D. Anderson Cancer Center-Houston, Houston, TX Poster

30. (707.3/Z2) Rats treated chronically with NMDA may be an animal model of upregulated brain arachidonic acid metabolism in bipolar disorder (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *H.-J. LEE, J. S. RAO, L. CHANG, S. I. RAPOPORT, R. P. BAZINET; Brain Physiol & Metabolism Section, Natl. Instit Aging/Natl Instit Hlth., Bethesda, MD Poster

'Phospholipid' abstracts 1>30 | 31>50 | <CTRL><F> to search through this document

31. (707.4/Z3) Hyperglutamatergic state in postmortem frontal cortex of bipolar disorder patients (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *H.-W. KIM, H.-J. LEE, S. RAPOPORT, J. RAO; Nat Inst. Hlth., Bethesda, MD Poster

32. (707.5/Z4) Up-regulated arachidonic acid cascade enzymes and their transcription factors in post-mortem frontal cortex from bipolar disorder patients (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *J. S. RAO, H.-W. KIM, H.-J. LEE, S. I. RAPOPORT; Brain Physiol & Metabolism, NIH, Bethesda, MD Poster

33. (782.2/F19) Functional modulation of P2X1 and P2X4 receptor-channels by phosphoinositides (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract *L.-P. BERNIER1, A. ASE1, D. BLAIS1, É. BOUÉ-GRABOT2, P. SÉGUÉLA1; 1Montreal Neurological Inst., McGill Univ., Montreal, PQ, Canada; 2Cnrs umr 5227, Univ. Victor Segalen Bordeaux 2, Bordeaux, France Poster

34. (782.12/F29) Potentiation of nucleotides-induced P2X7 receptor activation by lysophosphatidylcholine in mouse microglial cells (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract T. TAKENOUCHI1, *S. SUGAMA2, M. SATO1, H. KITANI1; 1Transgenic Animal Res. Ctr., Natl. Inst. of Agrobiological Sci., Tsukuba, Japan; 2Dept. of Physiology, Nippon Med. Sch., Tokyo, NF, Japan Poster

35. (795.22/N14) Paraxonase 1 genetic variations affect both risk level and cholinergic system integrity in the human brain with Alzheimer’s disease (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract *V. LEDUC1, L. THÉROUX2, D. DEA2, J. POIRIER2; 1Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 2Douglas Mental Hlth. Institute, McGill Univ., Montreal, PQ, Canada Poster

36. (803.1/T12) Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem/progenitor cells toward a site of spinal cord injury (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *A. KIMURA1,2,3, T. OHMORI2, R. OHKAWA4, S. MADOIWA2, J. MIMURO2, T. MURAKAMI3, E. KOBAYASHI3, Y. HOSHINO1, Y. YATOMI4, Y. SAKATA2; 1Orthopaedic Surgery, 2Res. Div. of Cell and Mol. Medicine, Ctr. for Mol. Med., 3Div. of Organ Replacement Research, Ctr. for Mol. Med., Jichi Med. Univ., Shimotsuke, Japan; 4Dept. of Lab. Med., The Univ. of Tokyo Sch. of Med., Tokyo, Japan Poster

37. (806.28/W18) Changes in neuromolecular measures with cognitive function in chronic schizophrenia (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *K. PANCHALINGAM1, R. J. MCCLURE2, G. GOLDSTEIN3, J. A. STANLEY4, J. W. PETTEGREW1; 1Dept Psychiatry, Univ. Pittsburgh Sch. Med., Pittsburgh, PA; 2Dept. of Psychiatry, Univ. of Pittsburgh Med. Ctr., Pittsburgh, PA; 3Dept of Psychiatry, VA Pittsburgh HCS, Pittsburgh, PA; 4Wayne State Univ. Sch. of Med., Detroit, MI Poster

38. (820.15/FF14) Modulation of P2X3 and P2X2/3 sensory purinoceptors by phosphoinositides (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract *G. MO, L.-P. BERNIER, A.-J. CHABOT-DORE, D. BLAIS, P. SEGUELA; McGill Univ., Montreal, PQ, Canada Poster

39. (853.3) A new model for voltage-gated Ca2+ current inhibition by the Gq-mediated slow pathway (Wednesday, Nov 7 2007 1:30 PM - 1:45 PM) Abstract *A. R. RITTENHOUSE1, L. LIU1, J. F. HENEGHAN1, T. MITRA-GANGULI1, M. L. ROBERTS-CROWLEY1, J. V. BONVENTRE2; 1Dept Of Physiol, Univ. Of Massachusetts Med. Sch., Worcester, MA; 2Harvard Inst. of Med., Harvard Med. Sch., Boston, MA Slide

40. (868.17/B11) Neuromolecular changes with development in healthy children (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract J. W. PETTEGREW1, K. PANCHALINGAM1, J. A. STANLEY2, *R. J. MCCLURE3; 1Dept. of Psychiatry, Univ. of Pittsburgh Sch. of Med., Pittsburgh, PA; 2Dept. of Psychiatry and Behavioral Neurosciences, Wayne State Univ. Sch. of Med., Detroit, MI; 3Dept. of Psychiatry, Univ. Pittsburgh Med. Ctr., Pittsburgh, PA Poster Session No.868: Cell Proliferation

41. (873.6/E16) Expression and functional roles of autotaxin in mouse nervous system (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract S. KOIKE, K. KEINO-MASU, *M. MASU; Dept Mol Neurobiol, Univ. Tsukuba, Tsukuba, Japan Poster

42. (877.13/G19) Role of PTEN on AMPAR mediated transmission in CA1 hippocampal neurons (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *S. JURADO, C. N. PETROK, J. A. ESTEBAN; Univ. Michigan Med., Ann Arbor, MI Poster

43. (886.13/M3) Intranasal sterically stabilized phospholipid nanomicellar VIP: a novel nanomedicine for Alzheimer's disease (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract A. PAI1, H. ONYUKSEL3, J. ARTWOHL3, *I. RUBINSTEIN2; 1Biopharmaceutical Sci., 2Dept Med. M/C 719, Univ. Illinois At Chicago, Chicago, IL; 3Univ. of Illinois at Chicago, Chicago, IL Poster

44. (897.11/U15) Reduced mitochondrial function but not mitochondrial mass in cerebellar granule cells of adult leaner mice (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *K. A. THUETT, B. BAWA, L. C. ABBOTT; Vet. Integrative Bioscie, Texas A&M Univ. Coll Vet Med., College Station, TX Poster

45. (901.15/Y14) Lipin1-regulated lipid metabolism is essential for Schwann cell myelination (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *R. CHRAST1, K. NADRA1, A.-S. DE PREUX1,2, J.-J. MEDARD1, G.-S. HAN3, S. GRES4, G. M. CARMAN3, J.-S. SAULNIER-BLACHE4; 1Dept Med. Genet, Univ. Lausanne, Lausanne, Switzerland; 2Grad. Program in Neurosciences, University of Lausanne, Switzerland; 3Dept. of Food Sci., Rutgers Univ., New Brunswick, NJ; 4Unite de Recherches sur les Obesites, Inserm-U586, Toulouse, France Poster

46. (907.20/DD20) Depletion of brain docosahexaenoic acid content and reproductive status affect expression of brain-derived neurotrophic factor in the female rat (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *M. K. OZIAS, K. E. MCCARSON, B. LEVANT; Pharmacol Toxicol & Therapeut., Univ. Kansas Med. Ctr., Kansas City, KS Poster

47. (907.22/DD22) Depletion of brain docosahexaenoic acid content and reproductive status affect dopamine and serotonin receptor binding in the female rat (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract P. F. DAVIS, *B. LEVANT; Dept Pharmacol, Univ. Kansas Med. Ctr., Kansas City, KS Poster

48. (914.12/II17) Identification of N-acyl-phosphatidylethanolamines precursors for anandamide in the rat brain (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract G. ASTARITA, *D. PIOMELLI; Dept Pharmacol, Univ. California Irvine, Irvine, CA Poster

49. (921.14/NN25) Activation of group I metabotropic glutamate receptors regulates endocannabinoid-mediated stress-induced analgesia through the phospholipase C/ diacylglycerol lipase pathway (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *L. GREGG, N. BOLTON, A. MOISE, R. SUPLITA, II, A. HOHMANN; Dept Psychol, Univ. Georgia, Athens, GA Poster

50. (932.23/WW18) UMP and DHA improve impaired memory in socially impoverished rats (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract S. HOLGUIN, J. MARTINEZ, Y. HUANG, J. LIU, S. TSANG, *R. J. WURTMAN; Brain & Cog Sci., MIT, Cambridge, MA Poster

'Phospholipid' abstracts 1>30 | 31>50 | <CTRL><F> to search through this document

'Lipoprotein' abstracts 1>30 | 31>60 | 61>86 | <CTRL><F> to search through this document

1. (104.4/BBB3) Multivariate methods for prediction in the analysis of fMRI data (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *A. H. ANDERSEN1, W. S. RAYENS2, Y. LIU2, C. D. SMITH3; 1Anat. and Neurobiology, 2Statistics, 3Neurol., Univ. of Kentucky, Lexington, KY Poster

2. (12.8) Apolipoprotein E4 domain interaction results in synaptic deficits and cognitive impairment in mice (Saturday, Nov 3 2007 2:45 PM - 3:00 PM) Abstract N. ZHONG1, G. RAMASWAMY1, K. SCEARCE-LEVIE1, *K. H. WEISGRABER1,2,3; 1Inst. Neruolog Dis., J David Gladstone Inst., San Francisco, CA; 2Dept. of Pathology, 3Cardiovasc. Res. Inst., Univ. of California, San Francisco, San Francisco, CA Slide

3. (14.4) Development of peripheral protein biomarker for the identification of Parkinson’s disease (Saturday, Nov 3 2007 1:45 PM - 2:00 PM) Abstract *G. A. ELDER1, N. HUMALA2, L. HO2, S. YEMUL2, A. ZAMPIERO2, K. MAREK3, G. M. PASINETTI2,4; 1Bronx VA Med. Ctr., Psychiatry Resch 3F22, Bronx, NY; 2Psychiatry, Mount Sinai Sch. of Med., New York, NY; 3Inst. for Neurodegenerative Disorders, New Haven, CT; 4Grecc, James J. Peters Veterans Affairs Med. Ctr., Bronx, NY Slide

4. (16.9) Investigating a role for PCSK9 in the regulation of cholesterol homeostasis during synaptic remodelling (Saturday, Nov 3 2007 3:00 PM - 3:15 PM) Abstract *S. BELANGER JASMIN1, V. PEARSON1, D. DEA2, L. THÉROUX2, J. POIRIER3; 1Dept Neurol & Neurosurg, 2Douglas Mental Hlth. Univ. Inst., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Slide

5. (30.6/A6) Opposite effects on cell proliferation by Wnt1 and Wnt7a proteins in cultured PC12 cells (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract P. SPINSANTI1, T. DE VITA1, A. CARUSO1, I. LISI1, D. MELCHIORRI1, A. CARICASOLE2, *F. CACIAGLI3, F. NICOLETTI1,4; 1Human Physiology and Pharmacol., Univ. of Rome "La Sapienza", Rome, Italy; 2Siena Biotech S.p.A., Siena, Italy; 3Dept Biomed Res., D'Annunzio Univ. Chieti, Chieti I-66013, Italy; 4I.R.C.C.S. I.N.M. Neuromed, Pozzilli, Italy Poster

6. (32.2/C8) Localization of functional Reelin receptors as revealed by alkaline phosphatase-Reelin fusion protein (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract T. UCHIDA1, A. BABA1, T. MIYATA2, K. NAKAJIMA3, *M. HATTORI1; 1Nagoya City Univ., Nagoya, Japan; 2Nagoya Univ., Nagoya, Japan; 3Keio univ., Tokyo, Japan Poster

7. (48.13/L2) Young but not aged human apoE4 targeted replacement mice show impaired LTP (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *S. YUN1,2, K. A. PARK1, P. SULLIVAN3, J. F. PASTERNAK1,2, B. L. TROMMER1,2; 1Res. Inst., Evan Northwes Hlthca, Evanston, IL; 2Dept. of Pediatrics and Neurol., Feinberg Sch. of Medicine, Northwestern Univ., Chicago, IL; 3Dept. of Medicine, Div. of Geriatrics and Ctr. for Aging, Duke Univ., Durham, NC Poster

8. (52.16/O9) The role of dietary lipids in brain aging and cognitive decline (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract L. R. FREEMAN1, C. STEVENS2, V. HALEY-ZITLIN2, K. SAMBAMURTI3, V. ZAMAN3, A. B. MOORE3, C. UMPHLET3, J. L. LOCKROW3, I. SINGH4, *A.-C. E. GRANHOLM3; 1Neurosci, Med. Univ. of South Carolina, Charleston, SC; 2Food Sci. and Human Nutr., Clemson Univ., Clemson, SC; 3Neurosci, 4Pediatrics, Med. Univ. of South Carolina, Charleston, SC Poster

9. (9.8) Role of toll like receptors 2 and 4 in adult neural stem cell function (Saturday, Nov 3 2007 2:45 PM - 3:00 PM) Abstract R. COVACU, T. OLSSON, *M. SVENSSON, L. BRUNDIN; Dept Clin. Neurosci/Neurosurg, Karolinska Inst., Stockholm, Sweden Slide

10. (90.24/RR20) Role of the glycoprotein Reelin for cognitive processes and synaptic plasticity in juvenile and adult rats (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract J. BROSDA, M. KOCH; Dept. of Neuropharmacology, Univ. of Bremen, Bremen, Germany Poster

11. (125.14) Estradiol modulates hypothalamic apolipoprotein AIV gene expression and satiating action in rats (Sunday, Nov 4 2007 11:15 AM - 11:30 AM) Abstract *M. LIU1, L. SHEN1, D. J. CLEGG2, S. C. WOODS2, P. TSO3; 1Dept Pathol & Lab. Med., 2Psychiatry, 3Pathology and Lab. Med., Univ. Cincinnati, Cincinnati, OH Slide

12. (131.3/C26) Reelin signaling facilitates maturation of CA1 glutamatergic synapses (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *S. QIU, E. J. WEEBER; Mol Physiol & Biophysics, Vanderbilt Univ., Nashville, TN Poster

13. (152.2/Q8) Isoform-specific effects of apolipoprotein E isoforms on the stability of amyloid Aß peptide protofibrils (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *T. HASHIMOTO, Y. HORI, H. NOMOTO, Y. NAGATA, T. IWATSUBO; Dept Neuropathol & Neurosci, Univ. Tokyo, Tokyo, Japan Poster

14. (152.8/Q14) Over-expression of ABCA1 in the brain increases lipidation of apoE and decreases both apoE and amyloid levels in the CNS (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *H. JIANG1,2, S. E. WAHRLE1,2, M. PARSADANIAN1,2, D. M. HOLTZMAN1,2; 1Dept. of Neurol., Washington Uni, Saint Louis, MO; 2Hope Ctr. for Neurological Disorders, Washington Univ., Saint Louis, MO Poster

15. (152.17/Q23) Loss of LR11/SorLA accelerates amyloidogenesis in vivo: evidence for a proximal role of LR11 in Alzheimer’s disease (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *S. E. DODSON1, S. C. CARTER1, V. KARMALI1, J. J. FRITZ1, T. WILLNOW2, A. I. LEVEY1, J. J. LAH1; 1Neurol., Emory Univ., Atlanta, GA; 2Max Delbrück Ctr. for Mol. Med., Berlin, Germany Poster

16. (153.5/R8) Macrophages degrade ß - amyloid by an apolipoprotein E isoform-dependent mechanism (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *S. M. PAUL, L. ZHAO, S. LIN, V. GELFANOVA, J. E. HALE, F. LIU, J. M. HUNTER, K. R. BALES; Lilly Rese Lab., Eli Lilly & Co, Indianapolis, IN

17. (153.12/R15) siRNA knockdown of ApoE in APP transgenic mice (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *M. FINN1,2, J.-T. KOENIGSKNECHT-TALBOO1,2, J. R. CIRRITO1,3,2,4, M. LI1,2, B. SNIDER1,2,4, J. GUSTIN5, J. MILBRANDT1,2,5,6, D. M. HOLTZMAN1,2,4,7; 1Dept. of Neurol., 2Hope Ctr. for Neurological Disorders, 3Psychiatry, 4Alzheimer's Dis. Res. Ctr., 5Pathology and Immunol., 6Intrnl. Med., 7Mol. Biol. and Pharmacol., Washington Univ., St. Louis, MO Poster

18. (153.13/R16) TGFBeta2-induced changes in lRP-1/TBetaR-V and the impact on lysosomal ABeta uptake and neurotoxicity (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *M. E. HARRIS-WHITE1, P. ESLAMI1, M. JOHNSON1, E. TERZAKARYAN1, S. FRAUTSCHY2; 1Dept Med., 2Dept Med. & Neurol, UCLA/Greater Los Angeles Hlth. Care Syst. Sepulveda, Sepulveda, CA Poster

19. (154.1/R22) Apolipoprotein E4 domain interaction results in an endoplasmic reticulum stress response in primary astrocytes (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *G. RAMASWAMY1, K. H. WEISGRABER1,2,3; 1Glad Inst. Neurol Dis., The J David Gladstone Inst. UCSF, San Francisco, CA; 2Dept. of Pathology, 3Cardiovasc. Res. Inst., Univ. of California, San Francisco, San Francisco, CA Poster

20. (154.12/S5) Cleavage fragments of Apolipoprotein E enhance neurotoxicity in an isoform-specific manner (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *K. L. YOUMANS1, C. YU2, K. A. CRUTCHER3, M. LADU2; 2Anat. and Cell. Biol., 1Univ. Of Illinois Chicag, Chicago, IL; 3Dept. of Neurosurgery, Univ. of Cincinnati, Cincinnati, OH Poster

21. (154.16/S9) Cellular expression and pH affect the proteolysis of human apolipoprotein E in transgenic mouse brain homogenates (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *S. B. SHELTON1, W. ZHOU2, P. M. SULLIVAN3, K. A. CRUTCHER1; 1Dept Neurosurgery, Univ. Cincinnati, Cincinnati, OH; 2Dept Neurol., Xuanwu Hosp., Beijing, China; 3Dept Med., Duke Univ., Durham, NC Poster

22. (154.17/S10) Cognitive impairment in APP23/ABCA1+/- mice - implications for the role of ABCA1 in Alzheimer’s Disease (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *I. M. LEFTEROV1, M. STAUFENBIEL2, R. KOLDAMOVA1; 1Enviro & Occup. Hlth., Univ. Pittsburgh, Grad. Sch. Publ. Hlth., Pittsburgh, PA; 2Novartis Inst. of BioMedical Res., CH-4002 Basel, Switzerland Poster

23. (156.1/T13) A new mouse model expressing the amyloid beta clearance receptor at the blood-brain barrier (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *B. A. LARUE1, T. CHENG2, C. PINKERT1, R. DEANE1, B. ZLOKOVIC1; 1Univ. Rochester, Rochester, NY; 2Univ. of Rochester, Rochester, NY Poster

24. (156.2/T14) Effects of human apoE2, E3, or E4 gene-targeted replacement on behavioral and cognitive performance in young male mice (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *T. J. KORNECOOK, A. P. MCKINNEY, J.-C. DODART; CNS Pharmacol., Merck, Boston, MA Poster

25. (160.6/W13) Investigation of difference in susceptibility to als in caucasian and african-american cohorts (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *E. USACHEVA1, M. SAEED1, W. CHEN1, N. SIDDIQUE1, J. L. HAINES2, M. A. PERICAK-VANCE3, T. SIDDIQUE1; 1Neurol., Northwestern Univ., Chicago, IL; 2Vanderbilt Univ., Nashville, TN; 3Univ. of Miami, Miami, FL

26. (168.12/CC17) Quercetin-3-glucoside protects SH-SY5Y cells against oxidative damage by inducing cholesterol and phospholipid biosynthesis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *R. SOUNDARARAJAN1, A. D. WISHART1, H. P. V. RUPASINGHE3, M. ARCELLANA-PANLILIO4, C. M. NELSON5, M. MAYNE6, G. S. ROBERTSON2; 1Dept Pharmacol, 2Psychiatry & Pharmacol., Dalhousie Univ., Halifax, NS, Canada; 3Dept. of Envrn. Sci., NS Agr. Col., Truro, NS, Canada; 4Biochem. and Mol. Biol., Univ. of Calgary, Calgary, AB, Canada; 5Family & Nutritional Sci., Univ. of Prince Edward Island, Charlottetown, PE, Canada; 6Inst. of Nutrisciences and Hlth., Natl. Res. Council Canada, Charlottetown, PE, Canada Poster

27. (198.1/ZZ10) Angiotensin II AT1 receptor blockade decreases the aldosterone synthesis and release during lipopolysaccharide-induced immune stress in the adrenal gland of the rat (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *E. SANCHEZ-LEMUS, Y. MURAKAMI, I. M. LARRAYOZ-ROLDAN, J. M. SAAVEDRA; Sect. Pharmacol, NIMH, NIH, Bethesda, MD Poster

28. (107.5) SorLA/LR11-Deficient Mice Demonstrate Accelerated Amyloid Pathology in a Mouse Model of Amyloidosis (Sunday, Nov 4 2007 10:20 AM - 10:55 AM) Abstract J. L. LAH; Neurol., Emory Univ., Atlanta, GA Symposium

29. (223.1) The linkage between cerebral glucose metabolism pattern and APOE4 gene dose predicts 4-year long-term memory decline (Sunday, Nov 4 2007 1:00 PM - 1:15 PM) Abstract *K. CHEN1,2, E. M. REIMAN1,3,4,2, G. E. ALEXANDER5,2, R. J. CASELLI6,2, O. SMILOVICI1,2, W. LEE1,2, C. RESCHKE1,2, D. BANDY1,2; 1Banner PET Ctr., Banner Alzheimer's Inst., Phoenix, AZ; 2Arizona Alzheimer's Dis. Consortium, Phoenix, AZ; 3Translational Genomics Res. Inst., Phoeinx, AZ; 4Univ. of Arizona, Tucson, AZ; 5Psychology, Arizona State Univ., Tempe, AZ; 6Mayo Clin., Scottsdale, AZ Slide

30. (223.2) FDG-PET imaging of amnestic pre-mci (Sunday, Nov 4 2007 1:15 PM - 1:30 PM) Abstract *R. J. CASELLI1, K. CHEN2, W. LEE2, G. E. ALEXANDER4, E. M. REIMAN3; 1Dept Neurol, Mayo Clin., Scottsdale, AZ; 2Biomath., 3Psychiatry, Banner Alzheimer Inst., Phoenix, AZ; 4Psychology, Arizona State Univ., Tempe, AZ Slide

'Lipoprotein' abstracts 1>30 | 31>60 | 61>86 | <CTRL><F> to search through this document

31. (223.3) Higher mid-life cholesterol levels are associated with hypometabolism in brain regions affected by Alzheimer's and normal aging (Sunday, Nov 4 2007 1:30 PM - 1:45 PM) Abstract *E. M. REIMAN1,3,4,5, K. CHEN2,5, R. J. CASELLI6,5, D. BANDY2,5, W. LEE2,5, O. SMILOVICI2,5, C. RESCHKE2,5, G. E. ALEXANDER7,5; 2Banner Good Sam PET Ctr., 1Banner Alzheimer's Inst., Phoenix, AZ; 3Translational Genomics Res. Inst., Phoenix, AZ; 4Univ. of Arizona, Tucson, AZ; 5Arizona Alzheimer's Dis. Consortium, Phoenix, AZ; 6Mayo Clin., Scottsdale, AZ; 7Psychology, Arizona State Univ., Tempe, AZ Slide

32. (223.13) Regional network of gray matter reductions associated with APOE e4 in cognitively normal young to middle-aged adults (Sunday, Nov 4 2007 4:00 PM - 4:15 PM) Abstract *G. E. ALEXANDER1,2, K. CHEN3,2, E. M. REIMAN3,2, T. L. MERKLEY1,2, M. ASCHENBRENNER1,2, D. BANDY3,2, R. J. CASELLI4,2, J. R. MOELLER5; 1Dept Psychol, Arizona State Univ., Tempe, AZ; 2Arizona Alzheimer's Consortium, Phoenix, AZ; 3Banner Alzheimer Inst., Banner Good Samaritan Med. Ctr., Phoenix, AZ; 4Neurol., Mayo Clin., Scottsdale, AZ; 5Psychiatry, Columbia Univ., New York, NY Slide

33. (252.11/K27) LRP4 may play a role in maintenance of synaptic integrity and neuronal cell survival through apoE/cholesterol (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *T. SUZUKI, Y. LU, Q.-B. TIAN; Neuroplasticity, Shinshu Univ. Grad Sch. Med., Matsumoto 390-8621, Japan Poster

34. (255.10/M24) Age-related differences in modulation of HSP70 induction and transport in cerebral cortex in the R6/2 transgenic mouse model of Huntington’s Disease (HD) (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *G. J. KLAPSTEIN1, D. H. LEE2, T. D. HULBERT2, K. D. KLAPSTEIN3, J. SCHULZE1, T. MENINI1; 1Dept Basic Sci., 2Col. of Osteo. Med., 3Col. of Hlth. Sci., Touro Univ-California, Vallejo, CA Poster

35. (260.4/Q26) ATP binding cassette transporter A1 (ABCA1) expression is upregulated in the mouse hippocampus following unilateral entorhinal cortex lesions (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *V. PEARSON1,2, S. BELANGER-JASMIN1,2, D. DEA1, L. THEROUX1, J. POIRIER1,2,3; 1Dept of Neurosci., Douglas Mental Hlth. Inst., Montreal, PQ, Canada; 2Dept. of Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Poster

36. (262.20/S18) Correlation between APOE -491AA promoter in e4 carriers and clinical deterioration in early stage of traumatic brain injury (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *X. SUN1, Y. JIANG2; 1Chongqing medical university, Chongqing, China; 2Dept. of Neurosurgery, The First Affiliated Hosp. of Luzhou Med. Col., Luzhou, China Poster

37. (331.7) Expression of cholesterol related genes is up-regulated in the Tg2576 mouse model of Alzheimer's disease (Monday, Nov 5 2007 9:30 AM - 9:45 AM) Abstract *H. K. WARWICK1, T. A. COMERY1, S. ASCHMIES1, E. KOURANOVA1, R. H. RING1, M. FOLLETTIE2, L. WANG2, A. HILL2, Y. KIRKSEY1, P. H. REINHART1, D. R. RIDDELL1; 1Discovery Neurosci., Wyeth Res., Monmouth Junction, NJ; 2Biol. Technologies, Wyeth Res., Cambridge, MA Slide

38. (378.7/Y4) The interaction between tissue-type plasminogen activator and the low density lipoprotein receptor-related protein induces activation of the NF-kB pathway during cerebral ischemia (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *M. YEPES1, X. BROTZGE2, R. POLAVARAPU2; 1Dept Neurol, 2Neurol., Emory Univ., Atlanta, GA Poster

39. (422.6/FFF28) ApoE4 affects spatial learning and memory in children (Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *S. F. ACEVEDO, J. RABER; Behav Neurosci, OHSU, Portland, OR Poster

40. (444.9) RanbpM, a novel LRP-interacting adaptor protein, promotes the amyloidogenic processing of APP (Monday, Nov 5 2007 3:00 PM - 3:15 PM) Abstract *M. K. LAKSHMANA, I. YOON, E. CHEN, E. H. KOO, D. E. KANG; UCSD, La Jolla, CA Slide

41. (474.1/N27) Selenoprotein p acts as a signaling molecule through the apolipoprotein e 2 receptor (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *M. M. PETERS1, K. E. HILL2, R. F. BURK2, E. J. WEEBER3; 1Mol. Physiology & Biophys, 2Div. of Gastroenterology, Hepatology, and Nutrition, Dept. of Med., 3Mol. Physiology & Biophysics, Vanderbilt Univ., Nashville, TN Poster

42. (483.22/U22) Synaptic changes in the outer plexiform layer of the PDAPP/APOE4 double-transgenic mouse retina (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *J.-D. DING1, B. MACE2, R. HERRMANN1, P. SULLIVAN2, C. BOWES RICKMAN1,3; 1Ophthalmology, 2Med., 3Cell Biol., Duke Univ. Med. Ctr., Durham, NC Poster

43. (484.14/V8) The effects of apolipoprotein E on the internalization and neurotoxicity of oligomeric beta-amyloid1-42 in neurons (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *Y. ZHU, M. LADU, C. YU; Dept Anat. & Cell Biol, Univ. of Illinois at Chicago, Chicago, IL Poster

44. (485.12/W7) Omega-3 fatty acid docosahexaenoic acid upregulates sorla/lr11, a sorting protein with reduced expression in sporadic Alzheimer disease (AD): potential for AD prevention (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *Q.-L. MA1,2, B. TETER1,2, T. MORIHARA3, O. J. UBEDA1,2, F. YANG1,2, W. BEECH1,2, G. P. LIM1,2, S. FRAUTSCHY1,2,4, G. M. COLE1,2,4; 1Sepulveda VA Med. Ctr., Greater Los Angeles Vets Affairs Hlth. Sys VA Med. Cntr, North Hills, CA; 2Dept. of Medicine, UCLA, North hills, CA; 3Psychiatry, Osaka Univ., Osaka, Japan; 4Dept. of Neurology, UCLA, North hills, CA Poster

45. (576.13/K23) Role of ApoE receptor, ApoER2, in synaptic transmission (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *Y. CHEN, U. BEFFERT, J. HERZ; UT Southwestern Med. Ctr., Dallas, TX Poster Session No.576: NMDA Receptors: Regulation I

46. (584.6/Q8) Reelin-dependant modulation of long term depression and long term potentiation in area CA1 of the hippocampus (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *N. K. SPEED1, J. L. BANKO2, E. J. WEEBER3; 1Dept Pharmacol., 2Dept Mol. Physiology/Biophysics, 3Dept Mol. Physiology/Biophysics, Dept Pharmacol., Vanderbilt Univ., Nashville, TN Poster Session No. 584: LTP: Postsynaptic Mechanisms IV

47. (592.3/V11) The LXR agonist TO-901317 increases HMG-CoA reductase activity in vivo and in vitro (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *M. P. BURNS1, G. W. REBECK1, G. P. ECKERT2; 1Dept. of Neurosci., Georgetown Univ., Washington, DC; 2Dept. of Pharmacol., Univ. of Frankfurt, Frankfurt, Germany Poster

48. (592.5/V13) Peptide mimetic therapeutic agents for inhibition of Aß aggregation (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract R. PULYK1, Y. UTKU3, J. PANKIEWICZ1, T. WISNIEWSKI2, K. KIRSHENBAUM3, *M. SADOWSKI4; 1Neurol., 2Neurology, Pathology, and Psychiatry, New York Univ. Sch. of Med., New York, NY; 3Chem., New York Univ., New York, NY; 4Neurol. and Psychiatry, New York Univ. Sch. Med., New York, NY Poster

49. (592.16/V24) Mechanism underlying apolipoprotein e isoform-dependent lipid efflux from cultured neurons (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract H. MINAGAWA1, A. WATANABE2, J.-S. GONG1, K. ZOU1, T. NAKAMURA1, S. LUND-KATZ3, M. C. PHILLIPS3, H. SAITO4, *M. MICHIKAWA1; 1Dept Alzheimer's Dis. Res., 2Dept Vascular Dementia Res., Natl. Centr Geriatrics Gerontol, Obu-shi, Japan; 3Children's Hosp. of Philadelphia, Univ. of Pennsylvania Sch. of Med., Philadelphia, PA; 4Dept. of Biophysical Chemistry, Kobe Pharmaceut. Univ., Kobe, Japan Poster

50. (625.13/VV1) ApoE is required for estradiol to increase neurite outgrowth in mouse olfactory explant cultures (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *A. HUSSAIN1, R. G. STRUBLE2, B. P. NATHAN1; 1Biol. Sci., Eastern Illinois Univ., Charleston, IL; 2Department of Neurol. and Ctr. for Alzheimer’s Dis. and Related Disorders, Southern Illinois Univ. Sch. of Med., Springfield, IL Poster

51. (638.23/FFF15) Effects of cranial Cesium irradiation on neuronal markers in human apoE transgenic female mice (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *L. E. VILLASANA1, C. POAGE1, T. PFANKUCH1, J. RABER1,2,3; 1Behav Neurosci, Oregon Hlth. & Sci. Univ., Portland, OR; 2Neurol., 3Div. of Neuroscience, ONPRC, OHSU, Portland, OR Poster6

52. The Neurobiolology of Apolipoprotein E: Potential Role in CNS Disorders and Alzheimer’s Disease (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract D. M. HOLTZMAN; Dept Neurol CSNSI, Washington Univ., St Louis, MO Special Lecture Session No. 544: The Neurobiology of Apolipoprotein E: Potential Role in CNS Disorders and Alzheimer’s Disease

53. (655.4) Transforming growth factor-beta1 associates with apoE-containing high-density lipoproteins: implications for neurodegeneration (Tuesday, Nov 6 2007 1:45 PM - 2:00 PM) Abstract *I. C. TESSEUR1, Y. HUANG2, J. CORN2, J.-S. GONG3, K. YANAGISAWA3, M. MICHIKAWA3, K. WEISGRABER2, T. WYSS-CORAY1,4; 1Dept Neurol, Stanford Univ. Sch. Med., Stanford, CA; 2Gladstone Inst. of Neurological Disease, Univ. of California San Francisco, San Francisco, CA; 3Dept. of Alzheimer's Dis. Res., Natl. Inst. for Longevity Res., Aichi, Japan; 4GRECC, VA Palo Alto Hlth. Care Syst., Palo Alto, CA Slide

54. (657.8) Behavioral and electrophysiological consequences of apoE isoform signaling in the adult mouse hippocampus (Tuesday, Nov 6 2007 2:45 PM - 3:00 PM) Abstract *K. M. KORWEK1, P. M. SULLIVAN3, E. J. WEEBER2; 1Neurosci., 2Mol. Physiology and Biophysics, Pharmacol., Vanderbilt Univ., Nashville, TN; 3Med., Duke Univ. Med. Ctr., Durham, NC Slide

55. (658.5) Role of soluble lipoprotein receptors in physiologic and therapeutic clearance of Aß (Tuesday, Nov 6 2007 2:00 PM - 2:15 PM) Abstract *B. V. ZLOKOVIC, R. D. BELL, A. SAGARE, B. JOHNSON, R. DEANE; Dept Neurosurg, Univ. Rochester, SMD, Rochester, NY Slide

56. (689.1/K13) Oxidative stress increases Aß accumulation by decreasing its efflux from the brain and enhances behavioral impairments in a mouse model of Alzheimer’s disease (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *Y. NISHIDA1, T. YOKOTA1, S. ITO2, N. IWATA3, T. UCHIHARA4, K. JISHAGE5, S. OHTSUKI2, T. C. SAIDO3, T. TERASAKI2, H. MIZUSAWA1; 1Neurol., Tokyo Med. and Dent. Univ., Bunkyo-ku, Japan; 2Mol. Biopharmacy and Genet., Tohoku Univ., Sendai, Japan; 3Lab. for Proteolytic Neurosci., RIKEN Brain Sci. Inst., Wako, Japan; 4Neurol., Tokyo Metropolitan Inst. for Neurosci., Fuchu, Japan; 5Chugai Res. Inst. for Med. Science, Inc., Gotenba, Japan Poster

57. (689.15/K27) A low-density lipoprotein receptor isoform lacking exon 4 is present in low-density lipoprotein receptor knock-out mouse brain (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *J. F. ABISAMBRA1,2, J. PADMANABHAN1,2, I. WEFES2, P. NEAME1, H. POTTER1,2; 1Johnnie B. Byrd, Sr. Alzheimer's Ctr. & Res. Inst., Tampa, FL; 2Univ. of South Florida, Tampa, FL Poster

58. (689.16/K28) Minor role of low-density lipoprotein receptor-related protein-1 in the brain-to-blood efflux transport system in mouse cerebral cortex (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *S. ITO1,2, S. OHTSUKI1,2, T. UENO1, J. KAMIIE1,2, T. TERASAKI1,2; 1Grad. Sch. of Pharm. Sci., Tohoku university, Sendai, Japan; 2SORST, Japan Sci. and Technol. Agency, Tokyo, Japan Poster

59. (689.17/L1) ApoE promotes the proteolytic degradation of Aß (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *C.-Y. LEE1, Q. JIANG1, S. MANDREKAR1, B. L. WILKINSON1, N. ZELCER2, K. MANN3, B. T. LAMB3, D. M. HOLTZMAN4, P. TONTONOZ2, G. E. LANDRETH1; 1Dept. of Neurosci., Case Western Reserve Univ., Cleveland, OH; 2Howard Hughes Med. Institute, Dept. of Pathology and Lab. Med., UCLA, Los Angeles, CA; 3Dept. of Neurosciences, Lerner Res. Inst., Cleveland Clin. Fndn., Cleveland, OH; 4Dept. of Neurol., Washington Univ. Sch. of Med., St. Louis, MO Poster

60. (689.18/L2) Apolipoprotein E-independent peripheral clearance of beta-amyloid peptide (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *J. M. HUNTER1, V. GELFANOVA2, J. E. HALE2, D. KOGER1, K. R. BALES1, S. M. PAUL1; 1Neurosci. Discovery, 2Applied Biochem/Proteomics, Eli Lilly and Co., Indianapolis, IN Poster

'Lipoprotein' abstracts 1>30 | 31>60 | 61>86 | <CTRL><F> to search through this document

61. (689.19/L3) LRP1 and RAGE regulate normal amyloid ß-peptide homeostasis in the CNS (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *A. P. SAGARE, R. DEANE, B. V. ZLOKOVIC; Dept Neurosurg, Univ. Rochester Med. Ctr, Box670, Rochester, NY Poster

62. (689.23/L7) The Nogo66 receptor binds b-amyloid42 (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *C. YANG, M.-Y. JUNG, F. QIAN, W. YANG, P. WEINREB, L. WALUS, T. ENGBER, B. PEPINSKY, W. MEIER, D. H. S. LEE; Biogenidec Inc, Cambridge, MA Poster

63. (692.11/N1) Polyphenolic compounds curcumin, ferulic acid and tannic acid enhance Apolipoprotein E secretion (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *S. CHEUNG1, J. LEE2, L. BAUM2; 1Med. & Therapeut., Chinese Univ. of Hong Kong, Hong Kong, ; 2Med. & Therapeut., Chinese Univ. of Hong Kong, Shatin, Hong Kong Poster

64. (701.7/T24) Potential role of apolipoprotein-E in clearance of apoptotic bodies (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *D. A. ELLIOTT, W. S. KIM, B. GARNER; POWMRI, Randwick, Australia Poster

65. (729.9/OO22) Estradiol replacement does not raise brain low-density lipoprotein receptor-related protein (LRP) in mice lacking apolipoprotein E (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *M. E. MCASEY1, X. CHENG2, M. LI1, S. B. RANDALL2, C. CADY3, B. P. NATHAN4, R. G. STRUBLE2; 1Obstetrics and Gynecology, 2Neurol. and Ctr. for Alzheimer's Dis. and Related Disorders, Southern Illinois Univ. Sch. Med., Springfield, IL; 3Biol., Bradley Univ., Peoria, IL; 4Biol. Sci., Eastern Illinois Univ., Charleston, IL Poster

66. (729.18/PP3) Ovariectomy attenuates apolipoprotein E (apoe) upregulation in the mouse olfactory bulb during axonal regeneration (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *R. G. STRUBLE1, E. ROSARIO3, S. LUDWIG4, M. KIRCHER4, C. CADY5, M. E. MCASEY2, B. NATHAN4; 1Ctr. Alzheimer Dis., 2Obstetrics and Gynecology, Southern Illinois Univ., Springfield, IL; 3Dept Biol. Sci., 4Biol. Sci., Eastern Illinois Univ., Charleston, IL; 5Biol., Bradley Univ., Peoria, IL Poster

67. (743.2/AAA25) Memory impairment occurred in mice deficient for lipoprotein lipase is probably caused by decrease of pre-synaptic vesicles (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *D. CHUI1, T.-T. LIU1, X. XIAN2, J. YU1, Y. MIAO1, Y. YU1, G. LIU2; 1NeuroScience Resch Inst., Peking Univ., Beijing, China; 2Inst. of Cardiovascular, Peking Univ., Beijing, China Poster

68. (762.14) Development of peripheral protein biomarkers for medically unexplained fatigue in gulf war-deployed veterans (Wednesday, Nov 7 2007 11:15 AM - 11:30 AM) Abstract *S. THOMAS1, L. HO1, S. YEMUL1, A. ZAMPIERO1, D. FASULO2, K. NOY2, B. H. NATELSON3, G. PASINETTI1; 1Psychiatry, Mount Sinai Sch. of Med., New York, NY; 2Siemens Corporate Res., Princeton, NJ; 3UMDNJ, Newark, NJ Slide

69. (795.5/M25) Interaction of the amyloid beta-peptide with the regulatory region of the APOE, APP and BACE gene promoters involved in Alzheimer’s disease (AD) (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract B. MALONEY1, Y.-W. GE1, J. A. BAILEY1, N. H. GREIG2, *D. K. LAHIRI1; 1Inst. Psychiat Res., Indiana Univ. Sch. Med., Indianapolis, IN; 2Lab. of Neurosciences, Natl. Inst. on Aging, Baltimore, MD Poster

70. (795.17/N9) The association of cholesterol levels and APOE promoter polymorphism with vascular dementia (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *F. LIU1, W.-D. XU2, C. JIA2, J. LI3; 1Dept Neurol., Fengtian Hosp Shenyang Med. Col., Shenyang, China; 2Fengtian Hosp. of Shenyang Med. Col., Shenyang, China; 3China Med. Univ., Shenyang, China Poster

71. (795.22/N14) Paraxonase 1 genetic variations affect both risk level and cholinergic system integrity in the human brain with Alzheimer’s disease (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract *V. LEDUC1, L. THÉROUX2, D. DEA2, J. POIRIER2; 1Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 2Douglas Mental Hlth. Institute, McGill Univ., Montreal, PQ, Canada Poster

72. (800.19/R16) Apolipoprotein E-mimetic peptides promote the survival and proliferation of oligodendrocyte precursor cells in vitro and remyelination in vivo (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract *F.-Q. LI1,2, J. E. NEIL2, C. A. COLTON1, M. P. VITEK1,2; 1Dept Med., Duke Univ. Med. Ctr., Durham, NC; 2Cognosci, Inc., Research Triangle Park, NC Poster

73. (839.9/TT5) Higher dropout rates in apolipoprotein E knockout mice compared to wild-type mice in the 5-choice serial reaction time task (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *J. A. SIEGEL1, T. S. BENICE, III1, J. RABER1,2,3; 1Behavioral Neurosci., 2Neurol., Oregon Hlth. & Sci. U., Portland, OR; 3Div. of Neurosci., Oregon Natl. Primate Res. Ctr., Portland, OR Poster

74. (840.22/UU13) Gene transfer of ApoE naked plasmid ameliorates Abeta-induced amnesia (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract *H. KURINAMI, N. SATO, D. TAKEUCHI, S. TAKEDA, M. SHINOHARA, R. MORISHITA; Grad Sch. Med., Osaka univ, suita city, Japan Poster

75. (852.4) The functional role of LRP1 in tissue-type plasminogen activator mediated activation of the NMDA receptor (Wednesday, Nov 7 2007 1:45 PM - 2:00 PM) Abstract A. M. MARTIN1, C. KUHLMANN2, S. JAEGER3, E. WALDRON3, A. ROEBROEK4, H. J. LUHMANN2, A. LAATSCH5, S. WEGGEN3, V. LESSMANN2, *C. U. PIETRZIK3; 1Inst. of Pathobiochemistry, 2Inst. of Physiology, Univ. of Mainz, Mainz, Germany; 3Inst. Physiol Chem & Pathobioch, Univ. Mainz, Mainz, Germany; 4Human Genet., KU Leuven and Flanders, Leuven, Belgium; 5Inst. of Mol. Cell Biol., Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Slide

76. (857.2) A novel role for copper: Disruption of LRP-dependent brain Aß clearance (Wednesday, Nov 7 2007 1:15 PM - 1:30 PM) Abstract *R. DEANE1, A. SAGARE1, M. COMA3, M. PARISI1, R. GELEIN2, I. SINGH1, B. ZLOKOVIC1; 1Dept Neurosurg, 2Envrn. Med., Univ. Rochester, Rochester, NY; 3Mol. Physiology and Channelopathies, Uni Pomeu Fabra, Parc de recerca Biomedica, Barcelona, Spain Slide

77. (857.5) Expression of ABC transporters in the human brain and their impact on cholesterol efflux and amyloid-beta processing (Wednesday, Nov 7 2007 2:00 PM - 2:15 PM) Abstract *W. S. KIM1, S. L. CHAN1, A. F. HILL2, B. GARNER1; 1Prince of Wales Med. Res. Inst., Sydney, Australia; 2Dept. of Biochem. and Mol. Biol., Univ. of Melbourne, Melbourne, Australia Slide

78. (867.10) Selected single-nucleotide polymorphisms and cognitive performance: differential associations (Wednesday, Nov 7 2007 3:15 PM - 3:30 PM) Abstract *N. RAZ1, K. M. RODRIGUE1, K. M. KENNEDY1, S. LAND2; 1Inst. Gerontol, 2Obstetrics and Gynecology, Wayne State Univ., Detroit, MI Slide

79. (884.6/K4) Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *G. BU, Q. LIU; Washington Univ., St. Louis, MO Poster Session No.884: Alzheimer's Disease: Physiological Functions of APP and APP Metabolites III

80. (884.8/K6) Amyloid precursor protein levels increase in the vascular endothelium of atherosclerotic and Alzheimer's disease tissue and partially mediate adhesion of monocytic cells to brain endothelium (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *S. A. AUSTIN, C. K. COMBS; Dept. Pharmacol, Physiol & Therapeut, Univ. North Dakota, Grand Forks, ND Poster

81. (885.2/K23) LR11 increases soluble APP release in response to PKC activation (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *K. L. SAGER, A. I. LEVEY, J. J. LAH; Neurol., Emory Univ., Atlanta, GA Poster

82. (888.2/N3) The Alzheimer's disease mouse model resource (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract M. SASNER, S. F. ROCKWOOD, C. M. LUTZ, L. DONAHUE, *K. R. JOHNSON; Genet. Resource Sci., Jackson Lab., Bar Harbor, ME Poster

83. (890.2/P2) Measuring apolipoprotein and tau tertiary structure using FLIM in tissue slices with significant autofluorescence (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract P. B. JONES1, A. ROZKALNE1, T. L. SPIRES-JONES1, O. BEREZOVSKA1, *B. J. BACSKAI2, B. T. HYMAN1; 1Massgeneral Inst. for Neurodegenerative Disorders, Harvard Med. Sch., Charlestown, MA; 2Dept Neurol., Mass Gen. Hosp., Charlestown, MA Poster

84. (890.13/P13) A consecutive analysis of biochemical markers associated with Alzheimer's disease (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *S. CULLEN1, P. CARMONEY2; 1Walden Univ., Parker, CO; 2Walden Univ., Minneapolis, MN Poster

85. (900.10/X10) Paraoxonase gene polymorphisms and lipid profile in Korean ischemic stroke patients (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *B. SHIN1,3, Y. KIM3, S. OH4, S. JEONG4, K. KIM2; 1Neurol., 2Pharmacol., Chonbuk Natl. Univ., Jeonju, Republic of Korea; 3Chonbuk Natl. Univ. Hosp. Res. Inst. of Clin. Med., Jeonju, Republic of Korea; 4Chonbuk Natl. Univ. Hosp., Jeonju, Republic of Korea Poster

86. (905.19/BB23) Receptor mediated apoE signaling cascades in glia (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *A. POCIVAVSEK1,2, M. P. BURNS1, G. W. REBECK1; 1Dept of Neurosci., Georgetown Univ., Washington, DC; 2Interdisciplinary Program in Neurosci., Washington, DC Poster

'Lipoprotein' abstracts 1>30 | 31>60 | 61>86 | <CTRL><F> to search through this document

'Fatty acids' abstracts 1>30 | 31>60 | 61>91 | <CTRL><F> to search through this document

1. (30.21/B15) 5-HT4 receptor-evoked neurogenesis in the adult murine enteric nervous system (ENS) (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *M.-T. LIU, Y.-H. KUAN, M. D. GERSHON; Dept Pathol & Cell Biol, Columbia Univ., New York, NY Poster

2. (39.21/G4) The endogenous cannabinoid anandamide inhibits nicotinic acetylcholine receptor function in mouse thalamic synaptosomes (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *M. OZ1, C. BUTT2, A. ALPTEKIN3, T. SHIPPENBERG1; 1Integrative Neurosci Section/IRP, NIDA, NIH, DHHS, Baltimore, MD; 2Div. of Structural Biol., West Virginia Sch. of Osteo. Med., Lewisburg, WV; 3Dept. of Anesthesiol., Sami Ulus Training and Res. Hosp., Ankara,, Turkey Poster

3. (43.2/H3) Modulation of Kv4 channel function by fatty acids (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract *L. M. BOLAND, M. DRZEWIECKI, A. BISBE, E. CASEY; Dept Biol., Univ. Richmond, Richmond, VA Poster

4. (43.3/H4) Oxidative downmodulation of Kv1.4- and Kv4.2-mediated K+-currents by arachidonic acid in transfected HEK 293 cells (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *P. R. ANGELOVA1, W. S. MUELLER2; 1Neurophysiol, Charite Med. Sch., Berlin, Germany; 2Neurosurgery, Univ. of New Mexico Med. Sch., Albuquerque, NM Poster

5. (49.20/M6) 4-Hydroxy docosahexaenoic acid and neuroprotectin D1 protect human neural cells from amyloid-ß peptide-induced neurotoxicity through different mechanisms (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *Y. ZHAO, J.-G. CUI, W. J. LUKIW; Neurosci., Lousiana State Univ. Hlth. Sci. Ctr., New Orleans, LA Poster

6. (61.1/V21) Intraventricular injections of propionic acid induce social, cognitive, and sensorimotor impairments in long evans rats (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *S. R. SHULTZ1, D. MACFABE2, S. SCRATCH2, J. JACKSON2, S. MARTIN2, F. BOON2, K. P. OSSENKOPP2, D. P. CAIN2; 1Neurosci., 2Univ. of Western Ontario, London, ON, Canada Poster

7. (61.2/V22) Spaced intraventricular injections of propionic acid in rats produces reversible social impairments and elicits more extensive neuroinflammatory effects than chronic injections: Implications for autism spectrum disorders (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract *D. F. MACFABE, Y. MOHAMMAD-ASEF, R. TAYLOR, J. HOFFMAN, L. TICHENOFF, D. P. CAIN, F. BOON, K. P. OSSENKOPP; Psychology/Psychiatry, Univ. Western Ontario, London, ON, Canada Poster

8. (61.3/V23) Microarray analyses of butyrate regulated genes: a window to CNS function (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *E. F. LA GAMMA1,2, B. B. NANKOVA2; 1Dir Regional Neonatal Ctr., Maria Fareri Children's Hosp., Valhalla, NY; 2Pediatrics, Biochem. and Mol. Biol., New York Med. Col., Valhalla, NY Poster

9. (61.4/V24) Short chain fatty acids regulate monoamine neurotransmission: possible relevance to autism spectrum disorders (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *B. B. NANKOVA1, D. F. MACFABE2, E. F. LA GAMMA1; 1Pediatrics & Biochem & Mol Biol, New York Med. Col., Valhalla, NY; 2Psychology and Psychiatry, Univ. of Western Ontario, London, ON, Canada Poster

10. (61.9/W1) Reduced startle response magnitude and prepulse inhibition in a propionic acid rodent model of autism spectrum disorder (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *K.-P. OSSENKOPP, K. A. FOLEY, R. TAYLOR, D. P. CAIN, M. KAVALIERS, D. F. MACFABE; Dept Psychol/Neurosci, Univ. Western Ontario, London, ON, Canada Poster

11. (151.16/P13) TGF-beta inhibits proteasome function and increases FABP5 levels in primary midbrain dopaminergic neurons in vitro (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract P. LINGOR1,2, J. KNÖFERLE1, S. RAMLJAK1, F. S. WOUTERS2, A. R. ASIF3, W. HOYER4, T. M. JOVIN4,2, I. ZERR1, M. BÄHR1,2; 1Dept. of Neurol., Univ. of Goettingen, Goettingen, Germany; 2DFG-Research Ctr. for Mol. Physiology of the Brain, 3Göttingen Proteomics Forum, Dept. of Clin. Chem., Univ. of Göttingen, Göttingen, Germany; 4Dept. of Mol. Biol., Max Planck Inst. for Biophysical Chem., Göttingen, Germany Poster

12. (172.11/FF28) The writing’s on the ‘invisible’ wall: Blurring the borders of childhood disorders (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract K. L. GILBY1, *D. C. MCINTYRE2, A. PALMER1, R. KEELEY1, V. ST-ONGE1, A. AZARBAR1; 1Inst. of Neurosci., 2Dept Psychol, Carleton Univ., Ottawa, ON, Canada Poster

13. (183.6/OO20) OL-135, a competitive inhibitor of fatty acid amide hydrolase, is efficacious in carrageenan-induced hyperalgesia (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *J. A. CASSEL1, N. CONWAY-JAMES2, P. J. LITTLE2, R. N. DEHAVEN1; 1Dept Molec Pharmacol, 2Dept In Vivo Pharmacol, Adolor Corp., Exton, PA Poster

14. (206.14/FFF9) Effects of ondansetron and URB597 on the expression of lithium-induced anticipatory nausea in rats (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *E. M. ROCK1, D. PIOMELLI2, L. A. PARKER1; 1Univ. of Guelph, Guelph, ON, Canada; 2Pharmacol., Univ. of California at Irvine, Irvine, CA Poster

15. (206.17/FFF12) The effect of URB-597 on the extinction of morphine induced place preference learning in rats (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract L. A. MANWELL, *L. A. PARKER; Dept Psychol, Univ. Guelph, Guelph, ON, Canada Poster

16. (244.4/G16) Characterization of the monoacylglycerol lipase (MGL) inhibitor URB602 (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *A. R. KING1, A. ROSENGARTH2, J. CLAPPER1, A. DURANTI3, A. TONTINI3, M. MOR4, S. RIVARA4, G. TARZIA3, D. PIOMELLI1; 1Pharmacol., 2Mol. Biol. and Biochem., Univ. of California, Irvine, Irvine, CA; 3Medicinal Chem., Univ. of Urbino, Urbino, Italy; 4Pharmaceut. Dept., Univ. of Parma, Parma, Italy Poster

17. (244.5/G17) The inhibition of the enzyme that degradates anandamide induces the cellular death in cerebellar granule neurons in mice (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *K. LUENEBERG1, G. DOMÍNGUEZ1, D. MILLÁN-ALDACO1, J. MORÁN1, D. PIOMELLI2, R. DRUCKER-COLIN1, E. MURILLO-RODRÍGUEZ1; 1Neurociencias, IFC/UNAM, Mexico City, Mexico; 2Pharmacol., Univ. of California, Irvine, Irvine, CA, USA, CA Poster

18. (245.14/G39) Modulation of hSlo BK current inactivation by fatty acid esters (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *X. SUN1, H. YAO1, D. ZHOU1, X. Q. GU1, G. G. HADDAD1,2,3; 1Dept Pediatrics, Univ. California San Diego, San Diego, CA; 2Neuroscence, Univ. of California San Diego, La Jolla, CA; 3The Rady Children's Hospital-San Diego, La Jolla, CA Poster

19. (256.14/N24) Walnuts can improve motor and cognitive function in aged rats (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *B. SHUKITT-HALE, V. CHENG, D. F. BIELINSKI, J. A. JOSEPH; USDA, ARS, Human Nutrit Res. Ctr. On Aging, Boston, MA Poster

20. (275.10/CC13) Endocannabinoid modulation of nicotine reward and dependence (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *L. L. MERRITT, B. R. MARTIN, A. H. LICHTMAN, C. WALTERS, M. DAMAJ; Pharmacol. & Toxicology, Virginia Commonwealth Univ., Richmond, VA Poster

21. (282.10/HH21) Fatty acid amide hydrolase is a viable target to reduce collagen-induced arthritis and pain (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract P. S. NAIDU1, D. DUDLEY2, B. R. MARTIN1, B. F. CRAVATT3, *A. LICHTMAN1; 1Dept Pharmacol & Toxicol, Virginia Commonwealth Univ., Richmond, VA; 2Mol. Pharmacol., Pfizer Global Res. and Develop., Ann Arbor, MI; 3The Skaggs Inst. for Chem. Biol. and Departments of Cell Biol. and Chem., The Scripps Res. Inst., La Jolla, CA Poster

22. (284.3/II21) In the rat formalin paw test, VER-154403, a FAAH inhibitor, is anti-nociceptive and increases peripheral and central levels of 2-arachidonylglycerol (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *G. A. KENNETT, L. BARRATT, S. GEOFFROY, R. HOWES, S. LIGHTOWLER, N. MATASSOVA, N. MONCK, A. PADFIELD, A. ROBERTSON, S. WALLS; Vernalis R & D Ltd, Wokingham, United Kingdom Poster

23. (299.6/UU2) Feeding effect of infection of adenoviral-mediated N-acylphosphatidylethanolamine phospholipase D in rat (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *J. FU, F. OVEISI, J. KIM, D. PIOMELLI; Dept Pharmacol., UC Irvine, Irvine, CA Poster

24. (299.17/UU13) The NPAS2 gene is crucial for behavioral and hepatic responsiveness to metabolic challenge (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *X. WU, S. RITTER; Programs in Neurosci., Washington State Univ., Pullman, WA Poster

25. (301.12/WW8) CNTF-activated astrocytes display metabolic plasticity and increased resistance to metabolic insults (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *C. ESCARTIN1,2,3,4, K. PIERRE3, A. COLIN2,1, E. BROUILLET2,1, T. DELZESCAUX2, M. GUILLERMIER2,1, M. DHENAIN2,1, N. DEGLON2,1, P. HANTRAYE2,1, L. PELLERIN3, G. BONVENTO2,1; 1CNRS URA 2210, CEA-DSV, I2BM, Orsay, France; 2MIRCen, CEA-DSV, I2BM, Fontenay-aux-roses, France; 3Dept. de Physiologie, Univ. de Lausanne, Lausanne, Switzerland; 4Current Affiliation: Dept. of Neurol., Univ. of California and Veterans Affairs Med. Ctr., San Francisco, CA Poster

26. (301.13/WW9) Central administration of a melanocortin antagonist stimulates hepatic lipogenic gene expression independent of changes in body weight (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *N. J. PORITSANOS, D. G. WONG, T. M. MIZUNO; Physiology, Univ Manitoba, Winnipeg, MB, Canada Poster

27. (315.7/HHH7) Identifying and quantifying molecular species of endocannabinoids in cerebrospinal fluids using liquid chromatography/mass spectrometry (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *A. N. FONTEH1, R. G. BIRINGER2, A. F. R. HÜHMER2, M. G. HARRINGTON1; 1Mol. Neurol Program, Huntington Med. Res. Int, Pasadena, CA; 2Thermo Fisher, San Jose, CA Poster

28. (315.16/HHH16) Small molecule profile analysis of the adult and juvenile zebra finch song nuclei by time of flight-secondary ion mass spectrometry (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *K. R. AMAYA1, J. V. SWEEDLER2, D. F. CLAYTON1; 1Cell Dev Biol., 2Chem., Univ. Illinois Urbana-Champaign, Urbana, IL Poster

29. (374.8/U22) Down-regulation of the neuroprotective CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *A. LUDANYI1, L. ERőSS2, S. CZIRJÁK2, J. VAJDA2, P. HALÁSZ3, M. WATANABE4, M. PALKOVITS5, Z. MAGLÓCZKY1, T. F. FREUND1, I. KATONA1; 1IEM HAS, Budapest, Hungary; 2Natl. Inst. of Neurosurgery, Budapest, Hungary; 3Natl. Inst. of Psychiatry and Neurology, Epilepsy Ctr., Budapest, Hungary; 4Dept. of Anat., Hokkaido Univ. Sch. of Med., Sapporo, Japan; 5Neuromorphological and Neuroendocrine Res. Laboratory, Dept. of Anat., Semmelweis Univ. and Hungarian Acad. of Sci., Budapest, Hungary Poster Session No.374: Epilepsy: Post-Seizure Modifications

30. (380.22/AA8) Zinc-induced apoptosis of GT1-7 cells are protected by mango (Mangifera indica L.) fruit: a candidate for treatment of neurodegeneration after ischemia (Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *M. KAWAHARA, K. KONOHA, T. NAGATA, Y. SADAKANE; Analytical Chem., Kyushu Univ. Hlth. & Welfare, Nobeoka, Japan Poster

'Fatty acids' abstracts 1>30 | 31>60 | 61>91 | <CTRL><F> to search through this document

31. (380.23/AA9) Conjugated Linoleic Acid protects cultured cortical neurons from glutamate toxicity (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *W. T. HUNT, C. M. ANDERSON; Pharmacol. & Therapeut., Univ. of Manitoba, Winnipeg, MB, Canada Poster

32. (417.12/CCC23) Endocannabinoid/GABA system in vlPAG during electroacupuncture-related cardiovascular responses (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *S. C. TJEN-A-LOOI1, P. LI2, J. C. LONGHURST2; 1SSC for Integrative Med., Univ. of California, Irvine, CA; 2Med., Univ. California, Irvine, CA Poster

33. (419.4/DDD24) Mechanisms of stable weight loss in honey bees (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *S. A. AMENT1, G. E. ROBINSON1,2,3; 1Neurosci. Program, 2Dept. of Entomology, 3Inst. for Genomic Biol., Univ. of Illinois, Urbana, IL Poster

34. (449.9) Novel protective mechanisms of acetyl-l-carnitine against alcohol-induced neurodegeneration (Monday, Nov 5 2007 3:00 PM - 3:15 PM) Abstract J. HAORAH1, *Y. PERSIDSKY2; 1Pharmacol. and Exptl. Neurosci., 2Dept Pathol and Microbiol, Univ. Nebraska Med. Ctr., Omaha, NE Slide

35. (458.22/D26) IL-6/sIL-6Ra chimera affects cerebral oligodendrocyte maturation and myelination in perinatal mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *S. H. BRUNSSEN1, J. GOHLKE2, A. D. TOEWS1, G. HARRY2; 1Univ. North Carolina- Chapel Hill, Chapel Hill, NC; 2NIEHS, NIH, DHHS, Research Triangle Park, NC Poster

36. (459.6/E8) Sterol responsive element binding proteins (SREBPs) are essential for proper myelination of peripheral nerve by regulating both myelin lipid and myelin protein synthesis (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *M. H. VERHEIJEN1, L. WRABETZ2, A. SMIT1; 1Mol. and Cell. Neurobi, Res. Inst. Neuroscienc, Amsterdam, The Netherlands; 2DIBIT, San Raffaele Scientific Inst., Milano, Italy Poster

37. (461.23/F39) Expression of the endocannabinoid receptor CB1 and the FAAH enzyme during retinal development in the rat (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract *N. A. ZABOURI1, J.-F. BOUCHARD2, C. CASANOVA2; 1 Optometry school, 2 Optometry school, Univ. of Montreal, Montreal, PQ, Canada Poster

38. (471.6/L19) AMPA receptor mediated toxicity in area CA1 of hippocampal slice cultures is selectively abolished by docosahexaenoic acid (DHA) (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *C. MENARD, A.-M. GAGNE, C. PATENAUDE, G. MASSICOTTE; UQTR, Trois-Rivieres, PQ, Canada Poster

39. (485.12/W7) Omega-3 fatty acid docosahexaenoic acid upregulates sorla/lr11, a sorting protein with reduced expression in sporadic Alzheimer disease (AD): potential for AD prevention (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *Q.-L. MA1,2, B. TETER1,2, T. MORIHARA3, O. J. UBEDA1,2, F. YANG1,2, W. BEECH1,2, G. P. LIM1,2, S. FRAUTSCHY1,2,4, G. M. COLE1,2,4; 1Sepulveda VA Med. Ctr., Greater Los Angeles Vets Affairs Hlth. Sys VA Med. Cntr, North Hills, CA; 2Dept. of Medicine, UCLA, North hills, CA; 3Psychiatry, Osaka Univ., Osaka, Japan; 4Dept. of Neurology, UCLA, North hills, CA Poster

40. (494.3/DD15) Synergistic effects of DHA dietary supplementation and exercise on synaptic plasticity and cognition (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract *Z. YING1, A. WU1, F. GOMEZ-PINILLA1,2,3; 1Dept Physiol Sci., 2Div. of Neurosurgery, 3Brain Injury Res.Ctr, UCLA, Los Angeles, CA Poster

41. (494.10/DD21) Omega-3 fatty acid dietary supplementation boosts the effects of exercise on counteracting the elevation of MAG and Nogo-A after brain trauma (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *G. CHYTROVA1, Z. YING1, F. GOMEZ-PINILLA1,2; 1Physiol Sci., 2Div. Neurosurgery, UCLA Brain Injury Res. Ctr., UCLA, Los Angeles, CA Poster

42. (501.25/JJ25) Anxiety-like behaviors in wild-type and dopamine D3 receptor knock-out (KO) mice: role of endocannabinoids and vanilloid TRPV1 receptors (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *V. MICALE1, L. CRISTINO2, A. TAMBURELLA1, S. PETROSINO3, G. LEGGIO1, V. GUGLIELMOTTI2, V. DI MARZO3, F. DRAGO1; 1Dept Exp & Clin. Pharmacol, Univ. Catania, Catania, Italy; 2Inst. di Cibernetica “E. Caianiello”, 3Inst. di Chimica Biomolecolare, Endocannabinoid Res. Group, CNR, 80078 Pozzuoli, Naples, Italy., Italy Poster

43. (509.2/PP5) Synthesis and evaluation of benzothiazole-based analogs as novel, potent fatty acid amide hydrolase inhibitors (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract X. WANG1, *K. L. KAGE1, D. ZHANG1, C. W. HUTCHINS2, L. N. MILLER2, M. E. UCHIC2, T. KOLASA2, O. F. EL-KOUHEN2, C. S. SUROWY2, J. D. BRIONI2, A. O. STEWART2; 2Abbott Labs, Abbott Park, IL Poster

44. (518.14/WW6) Fasting induced increase in long-chain fatty acid receptor GPR120 expression in the gonadotrope of the mouse anterior pituitary (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *R. MORIYAMA, S. IMOTO, K. NOSE, A. KOHAMA, C. DEURA, S. SHANO, N. FUKUSHIMA; Life Sci., Kinki Univ., Higashiosaka, Japan Poster

45. (523.2/AAA11) Response of hypothalamic peptide systems to dietary Omega-6:Omega-3 ratios in a model of metabolic syndrome (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *A. M. PINAWIN1, P. BURGHARDT2, E. S. KEMMERER2, B. J. BUCK2, L. KOCH3, S. L. BRITTON3, S. J. WATSON2, S. J. EVANS2, H. AKIL2; 2Mol. & Behavioral Neurosci. Inst., 3Physical Med. & Rehabil., 1Univ. of Michigan, Ann Arbor, MI Poster

46. (548.4) Phospholipase A2 reduction improves deficits in mouse model of Alzheimer’s disease (Tuesday, Nov 6 2007 8:45 AM - 9:00 AM) Abstract R. O. SANCHEZ-MEJIA1, J. W. NEWMAN2, S. TOH1, G.-Q. YU1, Y. ZHOU1, K. SCEARCE-LEVIE1, J. J. PALOP1, L. GAN1, *L. MUCKE3; 1Gladstone Inst. of Neurological Dis., San Francisco, CA; 2Dept. of Nutrition, Univ. of California, Western Human Nutr. Res. Center, U.S. Dept. of Agr., Davis, CA; 3Gladstone Inst. Neurol Dis., Univ. Calif San Francisco, San Francisco, CA Slide

47. (551.12) Is microglial apoptosis an early pathogenic change in cerebral X-ALD? (Tuesday, Nov 6 2007 10:45 AM - 11:00 AM) Abstract *F. EICHLER1, J.-Q. REN2, S. NAGPAL3, M. COSSOY5, A. M. RIETSCH5, M. FROSCH4, R. M. RANSOHOFF5; 2Radiology, 3Neurol., 4Pathology, 1Massachusetts Genl Hosp., Boston, MA; 5Neurol., Cleveland Clin., Cleveland, OH Slide

48. (565.23/E34) Fatty acid binding protein 7 is diurnally regulated in astrocytes and granule-cell progenitors in adult mouse hippocampus (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract J. R. GERSTNER1, Q. Z. BREMER3, J. C. P. YIN2, *C. F. LANDRY3; 1Neurosci. Training Program, 2Genet., Univ. of Wisconsin-Madison, Madison, WI; 3Dept Psychiatry, Univ. Wisconsin-Madison, Madison, WI Poster

49. (566.11/F10) Polyunsaturated fatty acids promote proliferation of neural progenitor cells in the hippocampal dentate gyrus (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *M. MAEKAWA1,2, M. MATSUMATA2,3, Y. OWADA4, M. KONTANI5, Y. HARA2,3, H. KAWASHIMA5, Y. KISO5, S. YUASA1, N. OSUMI2,3; 1Ultrastructural Res., Natl. Inst. Neurosci, Tokyo, Japan; 2Tohoku Univsity school of medicine, Sendai, Japan; 3CREST, JST, Kawaguchi, Japan; 4Yamaguchi Univ. school of medicine, Yamaguchi, Japan; 5Suntory Ltd., Osaka, Japan Poster

50. (595.14/X27) Upregulation of glutathione biosynthesis and decreased mitochondrial oxidative stress in rats fed the ketogenic diet (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *J. SCHUTZMAN1, S. G. JARRETT2, L.-P. LIANG2, M. PATEL2; 1Program in Neurosci., 2Pharmaceut. Sci., Univ. Colorado Hlth. Sci. Ctr., Denver, CO Poster

51. (595.15/X28) A ketogenic diet rescues the lethal phenotype and restores spontaneous synaptic transmission in succinic semialdehyde dehydrogenase deficiency (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *K. NYLEN1,4,5, J. P. VELAZQUEZ2,5, S. S. LIKHODII3,5, M. A. CORTEZ2,5, K. ADELI3, M. K. GIBSON6, W. BURNHAM4,5, C. SNEAD, III1,2,5,4; 1Neurosci. and Mental Hlth., 2Div. of Neurol., 3Paediatric Lab. Med., Hosp. for Sick Children, Toronto, ON, Canada; 4Dept. of Pharmacol., 5Univ. of Toronto Epilepsy Res. Program, Univ. of Toronto, Toronto, ON, Canada; 6Div. of Med. Genet., Children’s Hosp. of Pittsburgh, Pittsburgh, PA Poster

52. (600.18/BB14) The effects of acute administration of omega-3 phosphatidylcholine (PC) after spinal cord injury (SCI) in rats (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *S. TIAN1, N. A. STEPHENS1, J. LARSON-GONZALES1, R. J. GRILL2, L. M. LICHTENBERGER1; 1Integrative Biol & Pharmacol, 2Neurosurgery, Univ. Texas Med. Sch, Houston, Houston, TX Poster

53. (600.20/BB16) Differential roles for phospholipase A2family members after spinal cord injury (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *R. LOPEZ-VALES1, N. GHASEMLOU1, B. J. KERR1, E. BARBAYANNI2, K. BASKAKIS2, K. I. RATHORE1, V. CONSTANTINOU-KOKOTOU3, D. STEPHENS4, E. DENNIS4, T. SHIMIZU5, G. KOKOTOS2, S. DAVID1; 1Neurol., Ctr. for Res. in Neuroscience, McGill Univ., Montreal, PQ, Canada; 2Dept. of Chem., Univ. of Athens, Athens, Greece; 3Agr. Univ. of Athens, Athen, Greece; 4Dept. of Chem. & Biochemistry, Sch. of Medicine,, Univ. of California, San Diego, La Jolla, La Jolla, CA; 5Dept. of Biochem. and Mol. Biology, Fac. of Med., Univ. of Tokyo, Tokyo, Japan Poster

54. (602.23/DD23) Starving neurons show sex difference in autophagy (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *L. DU1, R. W. HICKEY2, H. BAYIR1, S. C. WATKINS3, V. A. TYURIN4, F. GUO3, P. M. KOCHANEK1, J. REN4, L. W. JENKINS5, V. E. KAGAN4, R. S. B. CLARK1; 1Critical Care Med., 2Pediatrics, 3Cell Biol. and Physiology, 4Envrn. and Occup. Hlth., 5Neurological Surgery, Univ. of Pittsburgh, Pittsburgh, PA Poster

55. (608.28/II13) Dietary omega-6:omega-3 ratios, endocannabinoids, mood and metabolic syndrome (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *E. S. KEMMERER1, P. R. BURGHARDT2, B. J. BUCK1, S. J. EVANS1; 1Psychiatry, 2Mol. and Behavioral Neurosci. Inst., The Univ. of Michigan, Ann Arbor, MI Poster

56. (634.4/BBB29) Positive effects of breastfeeding on neuronal integrity and function in boys performing a sustained attention task (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *R. K. MCNAMARA, J. ABLE, M. DELBELLO, W. WEBER, K. JARVIS, S. STRAKOWSKI, C. ADLER; Psychiatry, Univ. Cincinnatti, Cinicinnati, OH Poster

57. (658.2) Multiple mechanisms for omega-3 docosahexaenoic acid (DHA) prevention of AD pathogenesis (Tuesday, Nov 6 2007 1:15 PM - 1:30 PM) Abstract *G. M. COLE1, Q. MA1, F. YANG1, B. TETER1, T. MORIHARA2, O. UBEDA1, W. BEECH1, S. FRAUTSCHY1; 1GRECC (VA) & Med. (UCLA), VA Med. Ctr., Sepulveda, CA; 2Psychiatry, Osaka Univ., Osaka, Japan Slide

58. (672.12/C12) Glial progenitors, migratory streams and adult neurogenesis in the crustacean brain (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *D. C. SANDEMAN1, J. M. SULLIVAN2, J. L. BENTON1, B. S. BELTZ1; 1Neurosci. Program, Wellesley Col., Wellesley, MA; 2Neurosci. Program, Garvan Inst. of Med. Res., Sydney, Australia Poster

59. (698.3/R13) “Entourage” monoacylglycerols affect the function of human cerebral microvascular endothelial cells (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *M. SPATZ1,2, Y. CHEN2, E. SHOHAMI3, A. STRASSER2, R. MECHOULAM3, T. TOMORI2, R. MCCARRON2; 1Stroke Br., NIH-NINCDS, Bethesda, MD; 2Trama & Resuscitation Med. Dept., Naval Med. Rresearch Ctr., Silver Spring, MD; 3Hebrew Univ., Jerusalem, Israel 60. (700.1/S21) Identification of specific phospholipids targeted by oxidants during neuronal cell death: Roles of Ca2+-independent phospholipase A2 (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *B. S. CUMMINGS, B. PETERSON; Pharmaceut & Biomed Sci., Univ. Georgia, Athens, GA Poster

'Fatty acids' abstracts 1>30 | 31>60 | 61>91 | <CTRL><F> to search through this document

61. (702.9/U22) Methylenedioxymethamphetamine-induced mitochondrial damage in CNS: protective effects of acetyl-L-carnitine (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *E. P. ALVES1,2, Z. BINIENDA3, A. GONÇALVES1, E. FERNANDES4, F. CARVALHO2, T. SUMMAVIELLE1,5; 1Neurobehavior, IBMC, Porto, Portugal; 2REQUIMTE, Toxicology Dep., Fac. Pharm., Porto, Portugal; 3Div. Neurotoxicology, NCTR-FDA, Jefferson, AR; 4REQUIMTE, Physical.Chemistry Dep. Fac. Pharm., Porto, Portugal; 5Biomed. Sci. Dep., ESTSP, IPP, Porto, Portugal Poster

62. (705.14/X20) Magnesium valproate induces morphological changes in C6 glioma cells and inhibits glial-targeted transgene expression (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *J. A. BENITEZ1, B. SEGURA2, B. AVALOS2, G. CABRERA2, J. SEGOVIA-VILA1; 1Fisiologia, Biofisica y Neuroc, CINVESTAV, Mexico D.F., Mexico; 2Inst. Nacional de Cancerologia, Mexico D.F., Mexico Poster

63. (706.2/X28) Expression of the CB1 cannabinoid receptor in dorsolateral prefrontal and anterior cingulate cortices in schizophrenia (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *M. BISCAIA1, V. HAROUTUNIAN2, J. MEADOR-WOODRUFF1; 1UAB, Birmingham, AL; 2Psychiatry, Mount Sinai Sch. of Med., New York, NY Poster

64. (707.3/Z2) Rats treated chronically with NMDA may be an animal model of upregulated brain arachidonic acid metabolism in bipolar disorder (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *H.-J. LEE, J. S. RAO, L. CHANG, S. I. RAPOPORT, R. P. BAZINET; Brain Physiol & Metabolism Section, Natl. Instit Aging/Natl Instit Hlth., Bethesda, MD Poster

65. (707.11/Z10) Increased lipid peroxidation in postmortem cingulate cortex from subjects with bipolar disorder and schizophrenia (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *J.-F. WANG1, L. SHAO1, X. SUN1, L. T. YOUNG2; 1Ctr. for Addiction and Mental Hlth., Toronto, ON, Canada; 2Dept. of Psychiatry, Univ. of British Columbia, Vancouver, BC, Canada Poster

66. (711.17/CC2) The histone deacetylase inhibitor sodium butyrate enhances behavioral effects of antidepressant and stimulant drugs (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *F. SCHROEDER1, M. FEBO2, A. TAPPER1, C. FERRIS2, S. AKBARIAN1; 1Brudnick Neuropsych. R. Inst., 2Ctr. for Comparative Neuroimaging, Univ. Mass Med. Sch., Worcester, MA Poster

67. (713.12/DD17) Fatty acid-induced changes in intracellular calcium in gustatory and somatosensory cells: Mechanisms underlying the taste and texture of fat (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract T. YU, B. P. SHAH, D. R. HANSEN, *T. A. GILBERTSON; Bio, Utah Stat Univ., Logan, UT Poster

68. (777.28/C26) The role of FABP7 in postnatal hippocampal neurogenesis (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *M. MATSUMATA1, M. MAEKAWA2, Y. OWADA3, N. OSUMI1; 1Tohoku Univ. Sch. of Med., Sendai, Miyagi, Japan; 2Natl. Inst. of Neurosci., Kodaira, Tokyo, Japan; 3Yamaguchi Univ. Sch. of Med., Ube, Yamaguchi, Japan Poster

69. (796.3/N21) Large scale proteomic analysis of striatum in non-human primate Parkinson disease model with l-dopa induced dyskinesia (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract *B. L. SCHOLZ1, M. SVENSSON2, H. ALM1, K. SKÖLD2, K. KULTIMA1, Q. LI3, A. CROSSMAN4, E. BEZARD5, P. E. ANDREN6; 1Pharmaceut. Biosci., Uppsala Univ., Uppsala, Sweden; 2Denator AB, Uppsala, Sweden; 3ILAS, China Acad. of Med. Sci., Beijing, China; 4Fac. of Life Sciences, The Univ. of Manchester, Manchester, United Kingdom; 5CNRS UMR 5227, Univ. Victor Segalen, Bordeaux,, France; 6Lab. for Biol. and Med. Mass Spectrometry, Uppsala Univ., Uppsala, Sweden Poster

70. (804.20/U21) Metabolomic profiling of activated microglia by magnetic resonance spectroscopy (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *A. SIERRA1, Y. LI2, L. KARSTENS3, I. PELCZER3, P. DJURIC2, M. MALETIC-SAVATIC1; 1Neurol., 2Computer and Electrical Engin., Stony Brook Univ., NEW YORK, NY; 3Chem., Princeton Univ., Princeton, NJ Poster

71. (817.12/DD8) The role of the chorda tympani nerve in the gustatory processing of linoleic acid (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *J. M. STRATFORD, R. J. CONTRERAS; Florida State Univ., Tallahassee, FL Poster

72. (826.1/JJ18) Identification and characterization of potent, non-urea and non-carbamate, FAAH inhibitors (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *F. VINCENT, M. T. NGUYEN, S. GOWLUGARI, Q. ZHANG, C. CHOU, G. KIM, J. D. DEFALCO, D. STEIGER, D. S. REUBISH, C. L. VICTORIA, D. E. EMERLING, M. G. KELLY, J. KINCAID; Renovis, Inc., South San Francisco, CA Poster

73. (839.14/TT10) Effects of the FAAH inhibitor, URB597, on a visual reaction time task in rats (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract C. MAZZOLA1,3, J. MEDALIE1, L. V. PANLILIO1, *F. DRAGO3, M. SOLINAS4, B. HAHN2, S. GOLDBERG1, S. YASAR5; 1Preclinical Pharmacol. Section, Behavioral Neurosci. Res. Branch, Intramural Res. Progr, 2Neuroimaging Res. Branch, Intramural Res. Program, NIDA, NIH, DHHS, Baltimore, MD, 21224, USA, MD; 3Dept Exper & Clin. Pharmacol, Univ. Catania, 95125 Catania, Italy; 4Dept. Lab. de Biologie et Physiologie Cellulaires, CNRS-6187, Univ. de Poitiers, 86022, Poitiers, France, France; 5Div. of Geriatric Med., Johns Hopkins Med. School,, Baltimore, MD, 21224, USA, MD Poster

74. (843.7/WW20) Endocannabinoid system involvement in the motivational and reinforcing effects of nicotine (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract M. SCHERMA1,2, M. SOLINAS4, P. FADDA1, J. MEDALIE2, J. STROIK2, D. PIOMELLI5, G. TANDA3, S. YASAR6, *W. FRATTA1, S. GOLDBERG2; 1Dept. of Neurosci., Univ. of Cagliari, Monserrato, Italy; 2Preclinical Pharmacol. Section, Behavioral Neurosci. Res. Br., 3Psychobiology Section, Medications Discovery Res. Br., Natl. Inst. on Drug Abuse, Natl. Inst. of Health, Dept. of Hlth. and Human Services, Baltimore, MD; 4Lab. de Biologie et Physiologie Cellulaires, Univ. of Poitiers, Poitiers, France; 5Dipartment of Pharmacol., Univ. of California, Irvine, CA; 6Div. of Geriatric Med. and Gerontology, Dept. of Med., Johns Hopkins Univ. Sch. of Med., Baltimore, MD Poster

75. (853.1) Cytosolic phospholipase A2 is required for M1 muscarinic inhibition of N-type Ca2+ channel activity in sympathetic neurons (Wednesday, Nov 7 2007 1:00 PM - 1:15 PM) Abstract *L. LIU1, J. V. BONVENTRE2, A. R. RITTENHOUSE1; 1Dept of Physio, Univ. of Massachusetts Med. Sch., Worcester, MA; 2Harvard Inst. of Med., Harvard Med. Sch., Boston, MA Slide

76. (853.2) Modulation of voltage gated N-type calcium channels by substance P occurs via a novel pathway involving lipids and proteins (Wednesday, Nov 7 2007 1:15 PM - 1:30 PM) Abstract *T. MITRA-GANGULI, A. R. RITTENHOUSE; Physiology, Univ. Massachusetts Med. Sch., Worcester, MA Slide

77. (853.3) A new model for voltage-gated Ca2+ current inhibition by the Gq-mediated slow pathway (Wednesday, Nov 7 2007 1:30 PM - 1:45 PM) Abstract *A. R. RITTENHOUSE1, L. LIU1, J. F. HENEGHAN1, T. MITRA-GANGULI1, M. L. ROBERTS-CROWLEY1, J. V. BONVENTRE2; 1Dept Of Physiol, Univ. Of Massachusetts Med. Sch., Worcester, MA; 2Harvard Inst. of Med., Harvard Med. Sch., Boston, MA Slide

78. (857.6) The dietary omega-3 fatty acid DHA reduces cortical and striatal ß-amyloid load in APPswe/PS1?E9 transgenic mice (Wednesday, Nov 7 2007 2:15 PM - 2:30 PM) Abstract *B. M. BERG1,2, S. E. PEREZ2, O. LAZAROV3, M. NADEEM2, S. S. SISODIA4, K. A. MOORE1, E. J. MUFSON2; 1Nutr., Wyeth, Collegeville, PA; 2Neurological Sci., Rush Univ. Med. Ctr., Chicago, IL; 3Anat. and Cell Biol., Univ. of Illinois at Chicago, Chicago, IL; 4Neurobiology, Pharmacol. & Physiology, Univ. of Chicago, Chicago, IL Slide

79. (880.5/H14) Membrane raft association and posttranslational fatty acid modification of the dopamine transporter (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *J. D. FOSTER, S. D. ADKINS, R. A. VAUGHAN; Biochem & Molec Biol, Univ. N Dakota Sch. Med. & Hlth. S, Grand Forks, ND Poster

80. (882.6/I19) Electroacupuncture changes proteome in the substantia nigra of parkinson’s disease mice model (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *S.-T. KIM1,2,3, S. JEON2, S. KIM2,3, H.-J. YOO3, H.-J. LEE3, Y.-J. KIM4, T. H. JOH5, H.-J. PARK3; 1Dept. of meridian and acupoint, Col. of Oriental Med., Seoul, Republic of Korea; 2BK21 Oriental Med. Sci. Center, Kyunghee Univ., Seoul, Republic of Korea; 3Acupuncture & Meridian Sci. Res. Center, Kyunghee Univ., Seoul, Republic of Korea; 4Col. of Nursing Science, Kyung Hee Univ., Seoul, Republic of Korea; 5Dept. of Neurol. and Neuroscience, Weill Med. Col. of Cornell Univ., New York, NY Poster

81. (886.12/M2) Dietary depletion of the omega-3 fatty acid docosahexaenoic acid (DHA) activates tau kinases in APPsw mice: prevention by curcumin (Curc) (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *A. N. BEGUM1,3, M. R. JONES1, W. BEECH1,3, F. YANG1,3, B. HUDSPETH1,3, G. M. COLE1,3,2, S. A. FRAUTSCHY1,3,2; 1Dept Med., 2Dept Neurol., UCLA, Los Angeles, CA; 3Grecc, Greater LA Healthcare Syst., Sepulveda, CA Poster

82. (903.10/AA1) Docosahexanoic acid inhibits lipotoxicity in NGF differentiated PC12 cells and rat cortical cells (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *F. G. ALMAGUEL, M. DELEON; Loma Linda Univ., Loma Linda, CA Poster

83. (905.1/BB5) Monitoring of free fatty acids after human mesenchymal stem cell transplantation in ischemic rats (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract W. LI1,2, M. PAIK1, Y. AHN1,3, P. LEE1,2, O. BANG4, *G. LEE5,1; 1Inst. for Neuroregeneration and Stem Cell Research., Suwon, Republic of Korea; 2Neurol., 3Neurosurgery, Ajou Univ. Sch. of Medicine., Suwon, Republic of Korea; 4Neurol., Sungkyunkwan Univ. Sch. of Medicine., Seoul, Republic of Korea; 5Brain Dis. Res. Ctr., Ajou Univ., Suwon, Republic of Korea Poster

84. (907.20/DD20) Depletion of brain docosahexaenoic acid content and reproductive status affect expression of brain-derived neurotrophic factor in the female rat (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *M. K. OZIAS, K. E. MCCARSON, B. LEVANT; Pharmacol Toxicol & Therapeut., Univ. Kansas Med. Ctr., Kansas City, KS Poster

85. (907.22/DD22) Depletion of brain docosahexaenoic acid content and reproductive status affect dopamine and serotonin receptor binding in the female rat (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract P. F. DAVIS, *B. LEVANT; Dept Pharmacol, Univ. Kansas Med. Ctr., Kansas City, KS Poster

86. (911.11/FF28) Effects of modulation of endocannabinoid levels on the discriminative-stimulus effects of methamphetamine and cocaine in rats (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *Z. JUSTINOVA1,2, C. BARNES2, S. YASAR3, S. K. VADIVEL4, A. MAKRIYANNIS4, D. PIOMELLI5, S. R. GOLDBERG2; 1MPRC, Univ. Maryland Sch. Med., Baltimore, MD; 2Preclinical Pharmacol. Section, NIDA, IRP, NIH, DHHS, Baltimore, MD; 3Div. of Geriatric Med., Johns Hopkins Sch. of Med., Baltimore, MD; 4Ctr. for Drug Discovery, Northeastern Univ., Boston, MA; 5Dept. of Pharmacol., Univ. of California, Irvine, CA Poster

87. (914.2/II7) The effect of olfactory bulbectomy on amphetamine sensitization: a possible role for endocannabinoids (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *S. A. EISENSTEIN1, P. V. HOLMES2, A. G. HOHMANN2; 1Neurosci. Program, BHSI, 2Neurosci. and Behavior Program, Psychology, Univ. Georgia, Athens, GA Poster

88. (914.4/II9) Cannabinoids and acute immobilization stress modulate GABA release from rat olfactory bulb (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *E. H. JAFFE, A. DELGADO; Lab. Neuroquimica CBB, IVIC, Caracas 1020 A, Venezuela Poster

89. (914.6/II11) Inhibition of fatty acid amide hydrolase reduces nocifensive behavior in a murine model of cancer pain by a direct effect on primary afferent neurons (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *I. KHASABOVA1, C. HARDING-ROSE2, L. G. COICOU2, S. G. KHASABOV2, D. A. SIMONE2, V. S. SEYBOLD2; 1Dept Oral Sci., Univ. Minnesota, Minneapolis, MN; 2Univ. of Minnesota, Minneapolis, MN Poster

90. (914.18/II23) Emotional behavior and serotonergic neurotransmission in fatty acid amide hydrolase (FAAH) knock-out mice (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *F. R. BAMBICO1, T. CASSANO2, N.-T. NGUYEN1, N. KATZ1, T. MACHEDA2, M. MORGESE2, V. CUOMO3, D. PIOMELLI4, G. GOBBI1,5; 1Psychiatry, McGill Univ., Montreal, PQ, Canada; 2Dept Biomed. Sci., Univ. of Foggia, Univ Foggia, Italy; 3Dept. of Pharmacol. and Gen. Physiology, Univ. of Rome "La Sapienza", Rome, Italy; 4Ctr. for Drug Discovery and Dept. of Pharmacol., Univ. of California, Irvine, CA; 5Dept of Psychiatry, Ctr. de Recherche Fernand-Seguin, Montreal, PQ, Canada Poster

91 (937.15/AAA22) The role of the cannabinoid system in working memory: Effects of OL-135 and WIN 55212-2 on the 1-back procedure in rats and comparison to compounds known to disrupt memory in humans (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract C. THOMPSON1, T. KO1, J. EVENDEN1, D. WIDZOWSKI1, *B. BROCKEL2; 1Dept. of Neurosci. Biol., 2Dept Neurosci, AstraZeneca, Wilmington, DE Poster

'Fatty acids' abstracts 1>30 | 31>60 | 61>91 | <CTRL><F> to search through this document

'Lipid peroxidation' abstracts 1>30 | 31>65 | <CTRL><F> to search through this document

1. (52.15/O8) Age-related synaptic and non-synaptic mitochondrial bioenergetic changes in the Fischer 344 rat (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *L. K. GILMER, M. A. ANSARI, I. M. KASARSKIS, S. W. SCHEFF; Dept Anat & Neurobiol, Univ. Kentucky, Lexington, KY Poster

2. (56.2/R24) Intermittent hypoxia conditioning protects against ethanol withdrawal toxicity in hippocampal cell line (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract *A. M. WILSON; UNTHSC, Fort Worth, TX Poster

3. (56.14/S8) Estrogen regulation of the mitochondrial proteome: implications for neuroprotection and bioenergetics (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract *R. W. IRWIN1, J. NILSEN1, R. D. BRINTON1,2; 1Pharmacol., 2Programs in Neurosci., USC, Los Angeles, CA Poster

4. (58.11/U1) Oxidative stress and neuroinflammation in the streptozotocin treated Mouse brain (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *N. HAQUE, N. S. HAQUE; Dept Biol. Sci., New York City Coll Tech., New York, NY Poster

5. (143.2/J3) TRPA1 is a molecular sensor of oxidative stress (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *D. A. ANDERSSON, S. MOSS, C. GENTRY, S. BEVAN; King's Col. London, Wolfson CARD, London, United Kingdom Poster

6. (150.3/O7) LRRK2 is involved in the eIF4E/4E-BP pathway of protein translation, which regulates oxidative stress response and aging in dopaminergic neurons (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *Y. IMAI1,2, S. GEHRKE3, H.-Q. WANG4, R. TAKAHASHI4, K. HASEGAWA5, E. OOTA6, B. LU3; 1Karei kenkyusyo, Tohoku Univ., Sendai, Japan; 2CRESS, Sendai, Japan; 3Dept. Pathol., Stanford Univ. Sch. of Med., Palo Alto, CA; 4Dept. Neurol., Kyoto Univ. Grad. Sch. of Med., Kyoto, Japan; 5Dept. Neurol., Sagamihara Natl. Hosp., Sagamihara, Japan; 6Clin. Immunol., Kitasato Univ. Grad. Sch. Med. Sci., Sagamihara, Japan Poster

7. (156.7/T19) Oxidative stress is an early event in the brain of the Ts65Dn mouse, a model for Down syndrome (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *J. P. LOCKROW, L. WILLIS, K. SAMBAMURTI, A. C. GRANHOLM; Neurosciences, Med. Univ. of South Carolina, Charleston, SC Poster

8. (157.7/U18) Uridine prodrug PN401 improves memory in APPswe + P301L Tau model of Alzheimer’s disease (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract A. OLARIU1, Z. HU1, J. SHENG1, L. LIU1, R. A. G. GARCIA1, Q. LI1, D. BRENNEMAN1, R. W. VON BORSTEL1, *J. A. SAYDOFF2; 2Neurosci Res., 1Wellstat Therapeut., Gaithersburg, MD Poster

9. (158.5/V8) Neuroprotective effect of Melatonin against 6-Hidroxydopamine(Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *A. GUTIERREZ VALDEZ1,3,4, J. ORDOÑEZ LIBRADO2, V. ANAYA-MARTINEZ2, L. COLIN-BARENQUE2, E. MONTIEL-FLORES2, M. JUAREZ SERES2, R. GARCIA RUIZ2, P. ALEY-MEDINA2, J. ESPINOSA-VILLANUEVA2, A. SANTAMARIA DEL ANGEL3, V. RODRIGUEZ4, M. AVILA-COSTA2; 1UNAM, TLALNEPANTLA, Mexico; 2Neurosci., UNAM, Tlalnepantla, Mexico; 3Inst. Nacional de Neurologia y Neurocirugia, Df, Mexico; 4Biología Celular y Tisular, Facultad de Medicina UNAM, Df, Mexico Poster

10. (160.16/X3) The PGE2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *X. LIANG1, Q. WANG1, L. LOKTEVA1, T. NGUYEN2, R. M. BREYER3, T. MONTINE4, K. ANDREASSON1,2; 1Dept. Neurol & Neurol. Sci., Stanford Univ., Stanford, CA; 2Dept. Neurol., Johns Hopkins University, Sch. of Med., Baltimore, MD; 3Dept. Med., Vanderbilt Univ., Nashville, TN; 4Dept. Pathology, Univ. of Washington, Seattle, WA Poster

11. (168.12/CC17) Quercetin-3-glucoside protects SH-SY5Y cells against oxidative damage by inducing cholesterol and phospholipid biosynthesis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *R. SOUNDARARAJAN1, A. D. WISHART1, H. P. V. RUPASINGHE3, M. ARCELLANA-PANLILIO4, C. M. NELSON5, M. MAYNE6, G. S. ROBERTSON2; 1Dept Pharmacol, 2Psychiatry & Pharmacol., Dalhousie Univ., Halifax, NS, Canada; 3Dept. of Envrn. Sci., NS Agr. Col., Truro, NS, Canada; 4Biochem. and Mol. Biol., Univ. of Calgary, Calgary, AB, Canada; 5Family & Nutritional Sci., Univ. of Prince Edward Island, Charlottetown, PE, Canada; 6Inst. of Nutrisciences and Hlth., Natl. Res. Council Canada, Charlottetown, PE, Canada Poster

12. (225.8) Preconditioning with diethylmaleate modifies the brain DNA repair and anti-oxidative responses in mice treated with dieldrin (Sunday, Nov 4 2007 2:45 PM - 3:00 PM) Abstract *V. M. SAVA, A. VELASQUEZ, O. REUNOVA, J. SANCHEZ-RAMOS; Dept Neurol, Univ. South Florida, Tampa, FL Slide

13. (254.17/M10) Paraquat exposure during periods of neurodevelopment and the Parkinson’s disease phenotype (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *B. K. BARLOW1,2, J. KOCHAR2, K. PRASAD2, B. BUCKLEY2, O. MIROCHNITCHENKO2, E. K. RICHFIELD2, M. THIRUCHELVAM2; 1EOHSI, MD/PhD Program, Neurosci., Piscataway, NJ; 2Envrn. & Occup. Hlth. Sci. Institute, a joint institute of UMDNJ-Robert Wood Johnson Med. Sch. & Rutgers Univ., Piscataway, NJ Poster

14. (255.21/N7) The N-terminus of huntingtin protein is sensitive to thiol oxidation (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *J. H. FOX1, J. A. KAMA1, I. VOLITAKIS3, R. CHERNY3, A. I. BUSH3,2, S. M. HERSCH1; 1Dept Neurol., 2Dept Psychiatry, Mass. Gen. Hosp., Charlestown, MA; 3Dept Pathology, Univ. of Melbourne, Parkville, Australia Poster

15. (256.3/N13) Possible involvement of GABAergic mechanism in the protective effect of melatonin against acute immobilization stress-induced behavior alterations and oxidative damage in mice (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract A. KUMAR, R. GOYAL; Neuropsychopharmacology Div., PANJAB UNIVERSITY, CHANDIGARH, India Poster

16. (256.4/N14) Estradiol prevents ozone-induced increases in brain lipid peroxidation and impaired social recognition memory in female rats (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *R. GUEVARA-GUZMAN1, M. ANGOA-PÉREZ1, R. SANCHEZ-VEGA1, A. LARRAZOLO-LÓPEZ1, C. BERNAL1, K. M. KENDRICK2, S. RIVAS-ARANCIBIA1; 1Dept De Fisiologia, UNAM Fac Med., Mexico 04510 DF, Mexico; 2Cognitive and Behavioral Neurosci., The Babraham Inst., Cambridge, United Kingdom Poster

17. (256.5/N15) Exercise or vitamin E supplementation initiated in old age reduces cerebellar oxidative damage and improves motor function (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *L. CUI1, T. HOFER2, A. RANI1, C. LEEUWENBURGH2, T. C. FOSTER1; 1Dept Neurosci, McKnight Brain Inst. Univ. FL, Gainesville, FL; 2Dept. of Aging and Geriatrics, Institue on Aging,Univ FL, Gainesville, FL Poster

18. (256.6/N16) Oxidative stress and apoptotic biomarkers for the assessement of therapies in familial amyloid polyneuropathy associated with mutant transthyretin deposition (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *C. E. FLEMING, B. MACEDO, A. R. BATISTA, M. J. SARAIVA; Dept Molec Neurobiol, Inst. de Biologia Molec E Celular - IBMC, Porto, Portugal Poster

19. (256.10/N20) Cognitive performance, dementia and DNA/RNA oxidative damage in the oldest-old (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *L.-A. CHRISTIE1, M. M. CORRADA2, K. KAHLE-WROBLESKI1, C. W. COTMAN1, C. H. KAWAS2, E. HEAD2; 1Inst. Brain Aging & Dementia, 2Neurol., Univ. California, Irvine, Irvine, CA Poster

20. (256.18/N28) Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase/catalase mimetics in aged mice (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract A. CLAUSEN1, S. DOCTROW2, *D. S. ARST RUFFNER3, M. BAUDRY1; 1Univ. of Southern California Neurosci. Program, Los Angeles, CA; 2Proteome Systems, Woburn, MA; 3Pasadena, CA Poster Session No.256: Oxidative Stress and Synaptic Transmission

21. (261.3/R14) Acute post injury fasting is neuroprotective following traumatic brain injury: potential mechanisms and implications for treatment (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *L. M. DAVIS1, J. R. PAULY1, A. H. SEBASTIAN1, R. D. READNOWER1, J. M. RHO2, P. G. SULLIVAN1; 1Univ. Kentucky, Lexington, KY; 2Barrow Neurological Inst. and St. Joseph's Hosp. & Med. Ctr., Phoenix, AZ Poster

22. (265.12/U2) Edaravone, a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity and behavioral impairment in mice (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract T. KAWASAKI1, T. NASHIDA1, Y. AGO1, *K.-I. SAITO4, A. BABA2, T. MATSUDA1,3; 1Lab. Medicinal Pharmacol, Grad Sch. of Pharmaceut Sci., 2Lab. Mol Neuropharmacol, Grad Sch. Pharmaceut Sci., 3Ctr. for Child Mental Dev, Grad Sch. Med., Osaka Univ., Suita, Japan; 4Pharmaceuticals Lab. I, Mitsubishi Chem. Co, Aoba-ku, Yokohama 22, Japan Poster

23. (268.2/W6) Reversal of oxidative stress-induced anxiety by phosphodiesterase-2 inhibition (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract A. MASOOD1, A. NADEEM2, J. MUSTAFA2, *J. M. O'DONNELL3; 1Depts Behav Med. & Psych, Neurobiol & Anat, 2Dept Physiol & Pharmacol, 3Assi Dean Rese/Professor, West Virginia Univ. Hlth. Sci. Ctr., Morgantown, WV Poster

24. (301.13/WW9) Central administration of a melanocortin antagonist stimulates hepatic lipogenic gene expression independent of changes in body weight (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *N. J. PORITSANOS, D. G. WONG, T. M. MIZUNO; Physiology, Univ Manitoba, Winnipeg, MB, Canada Poster

25. (379.8/Y25) Poloxamer 188, an amphiphilic tri-block co-polymer, provides profound hippocampal neuroprotection following transient global forebrain ischemia in the Mongolian gerbil (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *J. D. MARKS1, A. DOI2, A. GARCIA, 3rd2, P. MYERS1, B. BUCHH1, J. SEAL1, J. WANG1; 1Dept Pediatrics, MC 6060, 2Dept Organismal Biol and Anat, Univ. Chicago, Chicago, IL Poster

26. (382.1/BB4) Bilirubin and glutathione: complementary antioxidant and neuroprotective functions (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract *T. W. SEDLAK1, M. SALEH2, S. H. SNYDER3; 1Psychiatry and Behavioral Sci., Johns Hopkins Sch. of Medici, Baltimore, MD; 2Neurosci., 3Neuroscience, Psychiatry and Behavioral Sci., Johns Hopkins Sch. of Med., Baltimore, MD Poster

27. (387.21/FF1) Morphine-induced withdrawal syndrome was exacerbated in gpx(-/-) and catalase(-/-) double knock out mice (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract H. KIM1, S. JANG1, H. LIM1, J.-C. JUNG1, *S. OH2; 1Neurosci., Sch. of Med. Ewha Womans Univ., Seoul, Republic of Korea; 2Dept Neurosci, Col. Med, Ewha Womans Univ., Seoul 158-710, Republic of Korea Poster

28. (443.1) Effects of cholesterol oxidation products on exocytosis in pheochromocytoma-12 cells (Monday, Nov 5 2007 1:00 PM - 1:15 PM) Abstract *W. ONG; Dept Anat., Natl. Univ. Singapore, Singapore 119260, Singapore Slide

29. (447.6) Seasonal influences on neuroinflammation and neuronal death (Monday, Nov 5 2007 2:15 PM - 2:30 PM) Abstract K. V. KARELINA1, Z. M. WEIL1, N. ZHANG, MD2, B. C. TRAINOR2, R. J. NELSON3, *A. C. DEVRIES4; 1Neurosci. Grad. Studies Program, 2Psychology, 3Psychology and Neurosci., 4Psycholo, Ohio State Univ., Columbus, OH Slide

30. (448.1) The oxygen-sensitive transcriptome in stroke-related injury of the brain: a therapeutic window of opportunity (Monday, Nov 5 2007 1:00 PM - 1:15 PM) Abstract *C. L. RINK, S. KHANNA, N. OJHA, S. ROY, J. RADTKE, C. SEN; Surgery, The Ohio State Univ. Med. Ctr., Columbus, OH Slide

'Lipid peroxidation' abstracts 1>30 | 31>65 | <CTRL><F> to search through this document

31. (449.9) Novel protective mechanisms of acetyl-l-carnitine against alcohol-induced neurodegeneration (Monday, Nov 5 2007 3:00 PM - 3:15 PM) Abstract J. HAORAH1, *Y. PERSIDSKY2; 1Pharmacol. and Exptl. Neurosci., 2Dept Pathol and Microbiol, Univ. Nebraska Med. Ctr., Omaha, NE Slide

32. (485.7/W2) Inhibition of Abeta42 production by a histidine analogue (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract *D.-G. JO1,2, T. V. ARUMUGAM3, S.-C. TANG3, H.-N. WOO1, M. R. MUGHAL3, A. GUIOTTO4, M. P. MATTSON3; 1Sch. of Pharm., Sungkyunkwan Univ., Suwon, Republic of Korea; 2Lab. of Neurosciences, Natl. Inst. on Aging, Baltimore, MD; 3Lab. of Neurosciences, Natl. Insitute on Aging, Baltimore, MD; 4Univ. of Padova, Padova, Italy Poster

33. (494.17/DD27) Time-dependent changes in markers of oxidative stress following traumatic brain injury (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract M. ANSARI, K. ROBERTS, *S. W. SCHEFF; Ctr. Aging, Univ. Kentucky, Lexington, KY Poster

34. (498.6/GG13) Role of glutathione in schizophrenia? The effect of brain glutathione depletion on prepulse inhibition (PPI) in rats and mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *O. M. DEAN1, A. I. BUSH1, M. BERK2, D. L. COPOLOV3, M. VAN DEN BUUSE1; 1MHRI/Uni. Melb., Parkville, Australia; 2Clin. and Biomed. Sci., Univ. of Melbourne, Geelong, Australia; 3Monash Univ., Melbourne, Australia Poster

35. (520.16/XX25) Chronic intermittent hypoxia (CIH) alters the behavior of the pre-Bötzinger complex (pre-BötC) to oxygen manipulation and norepinephrine (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *A. J. GARCIA1, N. PRABHAKAR2, J.-M. RAMIREZ1; 1Organismal Biol & Anat, 2Ctr. for Systems Biology, Dept. of Med., Univ. Chicago, Chicago, IL Poster

36. (524.4/BBB4) Brain-derived neurotrophic factor (BDNF) induces anorexia and increases energy expenditure via corticotropin-releasing hormone (CRH)-dependent pathway (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *M. TORIYA1, T. ONAKA2, T. YADA3; 1Jichi Med. Univ., shimotsukeshi, Japan; 2Div. of Brain and Neurophysiology, Dept. of Physiology, 3Jichi Med. Univ., Shimotsukeshi, Japan Poster

37. (550.3) Delayed glial expression of Fas/FasL contributes to secondary cell death and can be therapeutically targeted following acute spinal cord injury (Tuesday, Nov 6 2007 8:30 AM - 8:45 AM) Abstract *S. L. ROBINS1,2,3, M. G. FEHLINGS1,2,4,3; 1Inst. Med. Sci., Univ. Toronto, Toronto, ON, Canada; 2Krembil Neurosci. Ctr., Univ. Hlth. Network, Toronto, ON, Canada; 3Dept. of Genet. and Develop., Toronto Western Res. Inst., Toronto, ON, Canada; 4Dept. of Surgery, Univ. of Toronto, Toronto, ON, Canada Slide

38. (550.5) Oxidative and nitrosative cell death induced by ß-amyloid and its prevention by some dietary and medicinal phytochemicals (Tuesday, Nov 6 2007 9:00 AM - 9:15 AM) Abstract *J.-H. JANG1, G. PARK2, Y.-J. SURH3; 1Col. of Oriental Med., Daegu Haany Univ., Daegu, Republic of Korea; 2Neurol. Dept., Columbia Univ., New York, NY; 3Col. of Pharm., Seoul Natl. Univ., Seoul, Republic of Korea Slide

39. (567.14/F39) 4-hydroxy-2-nonenal modifies neurofilament protein, causes aberrant axonal morphology, impairs axon outgrowth and mimics the effect of diabetes in cultured adult sensory neurons (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *E. K. AKUDE1,2, E. ZHEREBITSKAYA1, P. FERNYHOUGH1,2; 1Div. Neurodegen Disorders, St Boniface Res. Ctr., Winnipeg, MB, Canada; 2Pharmacol. & Therapeut., Univ. of Manitoba, Winnipeg, MB, Canada Poster

40. (594.16/X12) The autistic phenotype exhibits a remarkably localized modification of brain protein by products of free radical-induced lipid oxidation (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *X. ZHU1, T. A. EVANS1, S. L. SIEDLAK1, L. LU2, W. MCGINNIS3, R. J. CASTELLANI4, R. G. SALOMON2, M. A. SMITH1, G. PERRY1,5; 1Pathology, 2Chem., Case Western Reserve Univ., Cleveland, OH; 3Oxidative Stress In Autism Study, Ashland, OR; 4Pathology, Univ. of Maryland, Baltimore, MD; 5Col. of Sci., Univ. of Texas at San Antonio, San Antonio, TX Poster

41. (595.14/X27) Upregulation of glutathione biosynthesis and decreased mitochondrial oxidative stress in rats fed the ketogenic diet (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *J. SCHUTZMAN1, S. G. JARRETT2, L.-P. LIANG2, M. PATEL2; 1Program in Neurosci., 2Pharmaceut. Sci., Univ. Colorado Hlth. Sci. Ctr., Denver, CO Poster

42. (596.11/Y12) Extracelluar calcium-dependent mitochondrial injury and cell death by N-methyl-D-aspartate and 4-hydroxy-2(E)-nonenal (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract I. Y. CHOI1, H. KIM2, J. LIM1, *J. CHOI3,1, W.-K. KIM1; 1Neurosci., Col. of Medicine, Korea Univ., Seoul, Republic of Korea; 2Col. of Pharmacy, Kang Won Natl. Univ., Chunchon, Republic of Korea; 3The Scripps Res. Inst., La Jolla, CA Poster

43. (597.2/Y15) Ngb overexpression protects brain against global ischemia/reperfusion injury (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *R. C. LI1, S. Z. GUO1, K. R. BRITTIAN1, D. GOZAL1,2; 1Dept Pediatrics, Univ. Louisville, Louisville, KY; 2Dept of Pharmacol. & Toxicology, Univ. of Louisville, Louisville, KY Poster

44. (597.9/Y22) Astrocytes subjected to pressure undergo increased modifications by lipid peroxidation products (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *B. GOVINDARAJAN1,2, B. ANAND-APTE1, R. G. SALOMON2, S. BHATTACHARYA3; 1Opthalmic Res., Cole Eye Inst., Cleveland, OH; 2Chem., Case Western Reserve Univ., Cleveland, OH; 3Bascom Palmer Eye Inst., Univ. of Miami, Miami, FL Poster

45. (597.10/Y23) Ischemic stroke and distruption of iron homeostasis in mice (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *S. J. TEXEL1, J. ZHANG2, S. PIN2, R. KOEHLER2, Z. HARRIS2; 1Dept Neurosci, 2ACCM, Johns Hopkins Univ., Baltimore, MD Poster

46. (602.3/DD3) Mitochondrial uncoupling and SIRT1 inhibitors protect neurons against excitotoxic death by preventing NAD+ depletion (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *D. LIU1, M. PITTA1, M. GLEICHMANN1, K. MUSTAFA1, N. SOUZA-PINTO2, M. NASSAR1, R. TELLJOHANN1, C. WU1, R. CUTLER1, M. P. MATTSON1; 1Gerontol Res. Ctr., 2Lab. Mol. Gerontology, NIA/NIH, Baltimore, MD Poster

47. (602.21/DD21) MPTP treatment permanently alters mitochondrial bioenergetics in the rhesus monkey nigrostriatal system (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *J. D. PANDYA1,3, R. GRONDIN1,4, Z. ZHANG1,4, W. A. CASS1,4, A. CHEN2, J. E. SPRINGER2, G. A. GERHARDT1,4, D. M. GASH1,4, P. G. SULLIVAN1,3; 1Dept Anat. and Neurobiology, 2Dept Physical Med. and Rehabil., Univ. Kentucky, Lexington, KY; 3Spinal Cord & Brain Injury Res. Ctr., Lexington, KY; 4Morris K Udall Parkinson's Dis. Res. Ctr. of Excellence, Lexington, KY Poster

48. (676.16/E33) Methamphetamine dysregulates astrocytes functions, increasing oxidative stress (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *S. F. ALI1, H. JIANG2, L. RONGZHU2, D. MILATOVIC2, M. ASCHNER2; 1Neurochem.Lab.Div. of Neurotox, Natl. Ctr. Toxicological Resch/FDA, Jefferson, AR; 2Vaderbilt Univ. Med. Ctr., Dept. of Peadiatrics, Nashville, TN Poster

49. (686.10/I15) The neuroprotective role of estrogen in the paraquat + maneb mouse model of Parkinson’s disease (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract J. KOCHAR1, O. PROKOPENKO2, O. MIROCHNITCHENKO2, *M. J. THIRUCHELVAM1; 1Dept Env Occup. Med., 2Dept Biochem., UMDNJ - Robert Wood Johnson Med. Schl, Piscataway, NJ Poster

50. (689.1/K13) Oxidative stress increases Aß accumulation by decreasing its efflux from the brain and enhances behavioral impairments in a mouse model of Alzheimer’s disease (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *Y. NISHIDA1, T. YOKOTA1, S. ITO2, N. IWATA3, T. UCHIHARA4, K. JISHAGE5, S. OHTSUKI2, T. C. SAIDO3, T. TERASAKI2, H. MIZUSAWA1; 1Neurol., Tokyo Med. and Dent. Univ., Bunkyo-ku, Japan; 2Mol. Biopharmacy and Genet., Tohoku Univ., Sendai, Japan; 3Lab. for Proteolytic Neurosci., RIKEN Brain Sci. Inst., Wako, Japan; 4Neurol., Tokyo Metropolitan Inst. for Neurosci., Fuchu, Japan; 5Chugai Res. Inst. for Med. Science, Inc., Gotenba, Japan Poster

51. (700.1/S21) Identification of specific phospholipids targeted by oxidants during neuronal cell death: Roles of Ca2+-independent phospholipase A2 (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *B. S. CUMMINGS, B. PETERSON; Pharmaceut & Biomed Sci., Univ. Georgia, Athens, GA Poster

52. (700.3/S23) Atomic force microscopy (AFM) analysis of oxidative damage and antioxidant protection following hyperoxia and hydrogen peroxide treatment in human U87 glioblastoma cells (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *D. P. D'AGOSTINO1, J. E. OLSON2, J. B. DEAN1; 1Dept Mol. Pharmacol& Physiol, Univ. South Florida, Tampa, FL; 2Emergency Med., Wright State Univ., Dayton, OH Poster Session No.700: Cell Death Mechanisms: Oxidative Stress I

53. (700.12/T6) 4-Hydroxynonenal induces accumulation of zinc in lysosomes and their rupture in cultured cortical neurons (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *S.-J. LEE1, J. HWANG2, J.-Y. CHO1, J.-Y. KOH1; 1Neural injury Res. Lab., Univ. Ulsan Col. Med., Seoul, Republic of Korea; 2Inst. for Innovative Cancer Res., Asan Med. Ctr., Seoul, Republic of Korea Poster Session No.700: Cell Death Mechanisms: Oxidative Stress I

54. (702.9/U22) Methylenedioxymethamphetamine-induced mitochondrial damage in CNS: protective effects of acetyl-L-carnitine (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *E. P. ALVES1,2, Z. BINIENDA3, A. GONÇALVES1, E. FERNANDES4, F. CARVALHO2, T. SUMMAVIELLE1,5; 1Neurobehavior, IBMC, Porto, Portugal; 2REQUIMTE, Toxicology Dep., Fac. Pharm., Porto, Portugal; 3Div. Neurotoxicology, NCTR-FDA, Jefferson, AR; 4REQUIMTE, Physical.Chemistry Dep. Fac. Pharm., Porto, Portugal; 5Biomed. Sci. Dep., ESTSP, IPP, Porto, Portugal Poster Session No.702: Neuroprotective Mechanisms: Oxidative Stress

55. (702.13/U26) Photobiomodulation attenuates CNS oxidative stress in an animal model of diabetes (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *D. J. BAUER1, A. C. SNYDER2, R. W. WILSON, II2, C. L. SANDOVAL2, D. S. LARK2, S. GOPALAKRISHNAN2, J. T. EELLS2; 1Psychology, 2Col. of Hlth. Sci., Univ. WI- Milwaukee, Milwaukee, WI Poster

56. (702.19/V4) Compounds in Alaska wild bog blueberries abolish neutral sphingomyelinase activation by TNFalpha in neuronal cells (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *T. B. KUHN, B. M. BARTH, C. M. MCGILL, T. P. CLAUSEN, S. J. GUSTAFSON; Dept Chem. & Biochem., Univ. Alaska Fairbanks, Fairbanks, AK Poster

57. (707.11/Z10) Increased lipid peroxidation in postmortem cingulate cortex from subjects with bipolar disorder and schizophrenia (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *J.-F. WANG1, L. SHAO1, X. SUN1, L. T. YOUNG2; 1Ctr. for Addiction and Mental Hlth., Toronto, ON, Canada; 2Dept. of Psychiatry, Univ. of British Columbia, Vancouver, BC, Canada Poster

58. (736.8/UU21) NADPH oxidase mediates intermittent hypoxia induced spatial learning deficits (Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *B. W. ROW1, Y. CHENG3, L. SERPERO3, E. DAYYAT3, D. GOZAL2; 1Dept Pediat, 2Pediat, Pharmacol. & Toxicology, Univ. Lousiville, Louisville, KY; 3Pediatrics, Univ. of Louisville, Louisville, KY Poster

59. (764.12) Prevention of lipid peroxidation by NDGA ameliorates mitochondrial function and extends survival of animal model of Huntington's disease (Wednesday, Nov 7 2007 10:45 AM - 11:00 AM) Abstract *H. RYU1, J. KIM1, S. J. DEL SIGNORE1, K. CORMIER1, B. KOSARAS2, K. SMITH1, R. J. FERRANTE1, J. LEE1; 1Dept Neurol, Boston Univ. Sch. Med., Bedford, MA; 2Harvard Med. Sch., Boston, MA Slide

60. (766.5) Heme oxygenase (HO)-2 determines neuronal fate under oxidative stress(Wednesday, Nov 7 2007 9:00 AM - 9:15 AM) Abstract *Z.-G. JIANG, E. I. SCHWARTZ, V. M. NELSON, M. S. LEBOWITZ, H. A. GHANBARI; Neurodegenerative Dis., Panacea Pharmaceuticals, Inc, Gaithersburg, MD Slide

61. (766.6) Effects of oxidative stress on adult neurogenesis in the rat hippocampus (Wednesday, Nov 7 2007 9:15 AM - 9:30 AM) Abstract *S. L. RIVAS-ARANCIBIA1,2, M. ANGOA-PÉREZ1, R. SÁNCHEZ-VEGA1, X. ORTIZ-LEON1, G. BORGONIO-PÉREZ1, M. ZANARDO GOMES2, R. RAISMAN-VOZARI2; 1Dept De Fisiologia, Facultad De Medicina, UNAM, 04510 Mexico DF, Mexico; 2INSERM U679, Hôpital de la Salpêtrière, , Paris, France Slide

62. (802.14/T4) Inhibition of necrosis with the calpain inhibitor MDL28170 enhances the survival of Schwann cells transplanted into the injured adult rat spinal cord (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract *C. E. HILL1, S. J. RAFFA1, A. HURTADO3, M. B. BUNGE2; 1Miami Project, 2Miami Project, and Depts of Neurol Surgery, and Anat. and Cell Biol., Univ. Miami Miller Sch. Med., Miami, FL; 3The Intl. Ctr. for Spinal Cord Injury, Kennedy Krieger Inst. and the Dept of Neurol., Johns Hopkins Univerisity Sch. of Med., Baltimore, MD Poster

63. (897.13/U17) Oxidative stress as an early marker of retinal ganglion cell degeneration in the dba/2 mouse model of glaucoma (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract W. LAMBERT1, D. INMAN1, E. OGLESBY2, I. SOTO2, N. MARSH-ARMSTRONG2, D. CALKINS3, *P. J. HORNER4; 1Univ. of Washington, Seattle, WA; 2Johns Hopkins Univ., Baltimore, MD; 3Vanerbilt Univ., Nashville, TN; 4Univ. Washington, Seattle, WA Poster

64. (900.10/X10) Paraoxonase gene polymorphisms and lipid profile in Korean ischemic stroke patients (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *B. SHIN1,3, Y. KIM3, S. OH4, S. JEONG4, K. KIM2; 1Neurol., 2Pharmacol., Chonbuk Natl. Univ., Jeonju, Republic of Korea; 3Chonbuk Natl. Univ. Hosp. Res. Inst. of Clin. Med., Jeonju, Republic of Korea; 4Chonbuk Natl. Univ. Hosp., Jeonju, Republic of Korea Poster

65. (903.11/AA2) Haloperidol-induced neurotoxicity: possible mechanisms and its attenuation by curcumin (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *K. CHOPRA1, M. BISHNOI2, S. K. KULKARNI1; 1Univ. Inst. Pharm Sci., Neuropharmacology Res. Lab., Panjab University, Chandigarh, India; 2Ctr. with Potential for Excellence in Biomed. Sci. (CPEBS), Panjab University, Chandigarh, India Poster903. Neurotoxicity

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