Neurobiol Lipids 6, 3 (21 October 2007) find out how to cite this article or link to a particular abstract

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NEUROBIOLOGY OF LIPIDS SESSIONS 2007

Published online: 21 October, 2007 | Article readership

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This article alerts interested readers about neurobiology of lipids sessions of the 37th Society for Neuroscience (SfN) annual meeting, 3-7 November, 2007, San Diego, California. The abstracts were retrieved from the SfN web based abstract system as a result of the search for the key words cholesterol, phospholipid, lipoprotein, apolipoprotein, fatty acid, lipid peroxidation in abstract title or abstract text. Every abstract reference includes day/time, program number, presentation type (poster or slide show), location, authors list, authors' affiliation(s), abstract title, and the link to abstract text at the abstractsonline.com web site.

Note to readers: Please note that the presented list of abstracts may omit certain sessions due to search terms difference. This article thus does not aim to substitute your own search for Neuroscience 2007 abstracts at the AbstractsOnline web site, the online host of the SfN Annual Meeting abstracts 2007. If you notice an omission, please let us know.

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Disclaimer: the appearance of an abstract in this article is not an endorsement or approval of an abstract experimental/scientific content/conclusion. Within each category sessions are listed in the order of the assigned SFN program numbers.

	Further reading icons provide URL links to further/related reading suggested by abstract authors and/or NoL editors
	Editors' choice icons (when/if article is updated with editors' choice selection) will represent the noteworthy abstracts' selection of editors voted by the update date.

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

1. (11.10) TRO19622 is well tolerated and achieves target plasma concentrations in a Phase 1b study in ALS patients (Saturday, Nov 3 2007 3:15 PM - 3:30 PM) Abstract J.-L. ABITBOL1, A. VERSCHUEREN2, L. LACOMBLEZ3, V. CUVIER1, E. JOUVE2, *R. M. PRUSS1, O. BLIN2, V. MEININGER3, J. POUGET2; 1Res. &Develop., TROPHOS, Marseille Cedex 9, France; 2CPCET and Clinique de Neurologie Hôpital de la Timone, Marseille, France; 3La Pitié-Salpétrière, Paris, France Slide

2. (12.8) Apolipoprotein E4 domain interaction results in synaptic deficits and cognitive impairment in mice (Saturday, Nov 3 2007 2:45 PM - 3:00 PM) Abstract N. ZHONG1, G. RAMASWAMY1, K. SCEARCE-LEVIE1, *K. H. WEISGRABER1,2,3; 1Inst. Neruolog Dis., J David Gladstone Inst., San Francisco, CA; 2Dept. of Pathology, 3Cardiovasc. Res. Inst., Univ. of California, San Francisco, San Francisco, CA Slide

3. (16.9) Investigating a role for PCSK9 in the regulation of cholesterol homeostasis during synaptic remodelling (Saturday, Nov 3 2007 3:00 PM - 3:15 PM) Abstract *S. BELANGER JASMIN1, V. PEARSON1, D. DEA2, L. THÉROUX2, J. POIRIER3; 1Dept Neurol & Neurosurg, 2Douglas Mental Hlth. Univ. Inst., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Slide

4. (21.7) Possible modulation of key enzyme of clock gene StAR for circadian glucocorticoid synthesis by chronic/acute exercise-induced stress protein HSP70 in adrenal cortex (Saturday, Nov 3 2007 2:30 PM - 2:45 PM) Abstract *Y. ATOMI1,2, M. FUJITA3, H. ARAI4; 1Transdisciplinary Initiative for Global Sustainability, 2Interdisciplinary Res. Syst. for Global Sustainability Sci., The Univ. of Tokyo, Tokyo, Japan; 3Dept. Immunol., Ntl Inst. Neurosci, Ntl Ctr. Neurol and Psych, Kodaira, Japan; 4Dept. of Life Sci., The Univ. Tokyo, Tokyo, Japan Slide

5. (33.14/D18) Role of prenylation on Rac1 activation and neurite outgrowth (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract F. SAMUEL, H. MO, *D. L. HYNDS; Dept Bio, Texas Woman's Univ., Denton, TX Poster

6. (43.5/H6) Compartmentalization of neuronal GIRK channels (Saturday, Nov 3 2007 1:00 PM - 2:00 PM) Abstract *J. O. COLON, K. WICKMAN; Pharmacol., Univ. Minnesota, Minneapolis, MN Poster

7. (44.12/I4) Lipid raft/caveolae localization and trafficking regulates Gs alpha/adenylyl cyclase signaling (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *J. A. ALLEN; U.Illinois Coll Med., Chicago, IL Poster

8. (45.11/J6) Lateral diffusion of lipids at inhibitory and excitatory synapses (Poster Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract M. RENNER1, C. SCHWEIZER1, D. CHOQUET2, *A. TRILLER1; 1Lab. Cell Biol Of Synapse, Dept Biol ENS, Paris 75005, France; 2Insitut Magendie, CNRS UMR 5091, Bordeaux, France Poster

9. (52.16/O9) The role of dietary lipids in brain aging and cognitive decline (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract L. R. FREEMAN1, C. STEVENS2, V. HALEY-ZITLIN2, K. SAMBAMURTI3, V. ZAMAN3, A. B. MOORE3, C. UMPHLET3, J. L. LOCKROW3, I. SINGH4, *A.-C. E. GRANHOLM3; 1Neurosci, Med. Univ. of South Carolina, Charleston, SC; 2Food Sci. and Human Nutr., Clemson Univ., Clemson, SC; 3Neurosci, 4Pediatrics, Med. Univ. of South Carolina, Charleston, SC Poster

10. (52.28/P1) siRNA silencing of cholesterol pathway molecules in neuron-enriched hippocampal cultures and cortical astroglial cultures of rat E18 brain tissues: Implications for brain aging (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *K.-C. CHEN, C. DILLEY, M. OLSON, N. M. PORTER, P. W. LANDFIELD; Dept Pharmacol, Univ. Kentucky, Lexington, KY Poster

11. (64.7/Y2) Effects of ethanol on the content of sphingosine-1-phosphate and phosphatidic acid in the developing brain (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *M. SAITO1,3, G. CHAKRABORTY2, R. WANG2, T. B. COOPER1,4, C. VADASZ2,3, M. SAITO2,3; 1Analytical Psycopharmacol, 2Lab. of Neurogenetics, Nathan S. Kline Inst., Orangeburg, NY; 3Psychiatry, New York Univ. Med. Ctr., New York, NY; 4New York State Psychiatric Inst., New York, NY Poster

12. (94.18/UU3) Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain (Saturday, Nov 3 2007 2:00 PM - 3:00 PM) Abstract D. M. O. RAMIREZ, *T. KOTTI, D. W. RUSSELL; Dept Molec Genet., UT Southwestern Med. Ctr., Dallas, TX Poster

13. (115.13) Vicious cycle in Alzheimer’s disease: Amyloid beta aggravates its own production (Sunday, Nov 4 2007 11:00 AM - 11:15 AM) Abstract *G. P. ECKERT1, I. PETERS1, W. G. WOOD2, W. E. MULLER1; 1Dept Pharmacol, Univ. Frankfurt, Frankfurt, Germany; 2Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide

14. (117.2) Reduced geranylgeranylation of rho family GTPases by lovastatin preserves oligodendrocyte progenitors and promotes myelin repair in an experimental autoimmune encephalomyelitis model (Sunday, Nov 4 2007 8:15 AM - 8:30 AM) Abstract *A. S. PAINTLIA1, M. K. PAINTLIA1, I. SINGH1, A. K. SINGH2; 1Pediatrics, 2Ralph H. Johnson V. A. Med. Ctr., MUSC, Charleston, SC Slide

15. (148.1/M26) Acute extraction of cholesterol with methyl-betha-cyclodextrin induces IP3-mediated calcium transients in cultured astrocytes (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract K. JEFTINIJA, E. W. ROWE, *S. JEFTINIJA; Biomed Sci., Iowa State Univ. Col. Vet Med., Ames, IA Poster

16. (151.11/P8) The membrane association of LRRK2 is isoprenylation-dependent (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *J. M. CORDY, C. H. HSU, B. WOLOZIN; Pharmacol., Boston Univ. Sch. Med., Boston, MA Poster

17. (151.21/P18) Transcriptome analysis of laser-captured dopaminergic neurons in mice overexpressing human wildtype alpha-synuclein (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *F. MORTAZAVI1, B. MEURERS1, M. S. OH2, D. ELASHOFF2, E. MASLIAH4, M.-F. CHESSELET1,3; 1Dept Neurol, 2Publ. Hlth. Dept., 3Dept Neurobiology, UCLA, Los Angeles, CA; 4Depts of Neurosciences and Pathology, UCSD, San Diego, CA Poster

18. (152.8/Q14) Over-expression of ABCA1 in the brain increases lipidation of apoE and decreases both apoE and amyloid levels in the CNS (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *H. JIANG1,2, S. E. WAHRLE1,2, M. PARSADANIAN1,2, D. M. HOLTZMAN1,2; 1Dept. of Neurol., Washington Uni, Saint Louis, MO; 2Hope Ctr. for Neurological Disorders, Washington Univ., Saint Louis, MO Poster

19. (152.14/Q20) Synaptic amyloid-beta correlates with oligomers and colocalizes with p-tau (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *K. GYLYS1, S. SOKOLOW1, K. HENKINS2, J. FEIN1, C. A. MILLER4, H. V. VINTERS3, G. M. COLE5; 1Schl Nursing & Brain Res. Inst., 2Interdepartmental Neurosci. Program, 3Pathology and Lab. Med., UCLA, Los Angeles, CA; 4Pathology , Neurology, and Program in Neurosci., Keck USC Sch. of Med., Los Angeles, CA; 5Sch. of Med., UCLA and VAMC GRECC, Los Angeles, CA Poster

20. (152.22/Q28) Lipid-ordering effects of celecoxib and fenofibrate in cellular membranes may contribute to enhanced amyloid-beta production (Poster Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract M. GAMERDINGER, A. CLEMENT, *C. W. BEHL; Med. Schl, Instit Physiol chemist & Path Johann, 55099 Mainz, Germany Poster

21. (153.2/R5) Increased autophagic activity might not automatically induce amyloid beta protein production (Poster Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract K. MAKIOKA, *T. YAMAZAKI, S. KAKUDA, K. OKAMOTO; Dept. of Neurol., Gumma Univ. Sch. of Medicnie, Maebashi, Japan Poster

22. (153.3/R6) Microglial mediated clearance of soluble Aß occurs via pinocytic mechanisms (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *S. D. MANDREKAR, Q. JIANG, E. REED-GEAGHAN, G. E. LANDRETH; Case Western Reserve, Cleveland, OH Poster

23. (154.9/S2) Increased autophagy is observed in Niemann-Pick disease type C cells (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract S. ISHIBASHI, T. YAMAZAKI, *K. OKAMOTO; Dept Neurol, Gunma Univ. Sch. Med., Maebashi, Japan Poster

24. (154.17/S10) Cognitive impairment in APP23/ABCA1+/- mice - implications for the role of ABCA1 in Alzheimer’s Disease (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *I. M. LEFTEROV1, M. STAUFENBIEL2, R. KOLDAMOVA1; 1Enviro & Occup. Hlth., Univ. Pittsburgh, Grad. Sch. Publ. Hlth., Pittsburgh, PA; 2Novartis Inst. of BioMedical Res., CH-4002 Basel, Switzerland Poster

25. (156.2/T14) Effects of human apoE2, E3, or E4 gene-targeted replacement on behavioral and cognitive performance in young male mice (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *T. J. KORNECOOK, A. P. MCKINNEY, J.-C. DODART; CNS Pharmacol., Merck, Boston, MA Poster

26. (156.10/T22) 27-hydroxycholestrol regulates GSK-3ß and the ATP-binding cassette transporters, ABCA1 and ABCG1, in organotypic slices from adult rabbit hippocampus (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *O. GHRIBI, S. SHARMA, A. HILFER, G. FEIST, J. GEIGER; Pharmacol, Physiol & Therapeut., UND Med. Sch., Grand Forks, ND Poster

27. (157.3/U14) Effect of chronic treatment with the LXR agonist, TO901317, in a triple transgenic model of Alzheimer's disease (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *J. L. SEARCY, J. T. PHELPS, E. M. BLALOCK, A. L. S. DOWLING, K.-C. CHEN, P. W. LANDFIELD, O. THIBAULT, N. M. PORTER; Mol&Biomed Pharmacol., Univ. Kentucky, Lexington, KY Poster

28. (160.10/W17) VAMP-associated protein-A inhibits lateral diffusion of membrane proteins in the endoplasmic reticulum (Sunday, Nov 4 2007 9:00 AM - 10:00 AM) Abstract *D. C. PROSSER, D. TRAN, P.-Y. GOUGEON, C. VERLY, J. K. NGSEE; Neurosci., Univ. Ottawa, Ottawa, ON, Canada Poster

29. (168.12/CC17) Quercetin-3-glucoside protects SH-SY5Y cells against oxidative damage by inducing cholesterol and phospholipid biosynthesis (Sunday, Nov 4 2007 11:00 AM - 12:00 PM) Abstract *R. SOUNDARARAJAN1, A. D. WISHART1, H. P. V. RUPASINGHE3, M. ARCELLANA-PANLILIO4, C. M. NELSON5, M. MAYNE6, G. S. ROBERTSON2; 1Dept Pharmacol, 2Psychiatry & Pharmacol., Dalhousie Univ., Halifax, NS, Canada; 3Dept. of Envrn. Sci., NS Agr. Col., Truro, NS, Canada; 4Biochem. and Mol. Biol., Univ. of Calgary, Calgary, AB, Canada; 5Family & Nutritional Sci., Univ. of Prince Edward Island, Charlottetown, PE, Canada; 6Inst. of Nutrisciences and Hlth., Natl. Res. Council Canada, Charlottetown, PE, Canada Poster

30. (198.1/ZZ10) Angiotensin II AT1 receptor blockade decreases the aldosterone synthesis and release during lipopolysaccharide-induced immune stress in the adrenal gland of the rat (Sunday, Nov 4 2007 8:00 AM - 9:00 AM) Abstract *E. SANCHEZ-LEMUS, Y. MURAKAMI, I. M. LARRAYOZ-ROLDAN, J. M. SAAVEDRA; Sect. Pharmacol, NIMH, NIH, Bethesda, MD Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

31. (211.8/III27) Neural coding of steroid mixtures: Olfactory perception in the American lobster (Sunday, Nov 4 2007 10:00 AM - 11:00 AM) Abstract *S. I. CROMARTY1, G. KASS-SIMON2; 1Dept Natural Sci., Assumption Col., Worcester, MA; 2Biol. Sci., Univ. of Rhode Island, Kingston, RI Poster

32. (107.2) Retromer-Deficient Mice Model Key Features of Alzheimer’s Disease (Sunday, Nov 4 2007 8:35 AM - 9:10 AM) Abstract K. DUFF; Pathology, Columbia Univ., New York, NY Symposium

33. (223.3) Higher mid-life cholesterol levels are associated with hypometabolism in brain regions affected by Alzheimer's and normal aging (Sunday, Nov 4 2007 1:30 PM - 1:45 PM) Abstract *E. M. REIMAN1,3,4,5, K. CHEN2,5, R. J. CASELLI6,5, D. BANDY2,5, W. LEE2,5, O. SMILOVICI2,5, C. RESCHKE2,5, G. E. ALEXANDER7,5; 2Banner Good Sam PET Ctr., 1Banner Alzheimer's Inst., Phoenix, AZ; 3Translational Genomics Res. Inst., Phoenix, AZ; 4Univ. of Arizona, Tucson, AZ; 5Arizona Alzheimer's Dis. Consortium, Phoenix, AZ; 6Mayo Clin., Scottsdale, AZ; 7Psychology, Arizona State Univ., Tempe, AZ Slide

34. (240.13/E36) Requirement for palmitoylation and raft insertion of Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKI? during cortical dendritogenesis (Sunday, Nov 4 2007 1:00 PM - 2:00 PM) Abstract *S. TAKEMOTO-KIMURA, N. AGETA-ISHIHARA, M. NONAKA, H. OKUNO, H. BITO; Dept. Neurochemistry, Univ. Tokyo Grad. Sch. of Med., Tokyo, Japan Poster

35. (252.11/K27) LRP4 may play a role in maintenance of synaptic integrity and neuronal cell survival through apoE/cholesterol (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *T. SUZUKI, Y. LU, Q.-B. TIAN; Neuroplasticity, Shinshu Univ. Grad Sch. Med., Matsumoto 390-8621, Japan Poster

36. (256.14/N24) Walnuts can improve motor and cognitive function in aged rats (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *B. SHUKITT-HALE, V. CHENG, D. F. BIELINSKI, J. A. JOSEPH; USDA, ARS, Human Nutrit Res. Ctr. On Aging, Boston, MA Poster

37. (257.4/O11) EcoG mapping and lesion verification of the origin of atypical absence epilepsy in GABAB R1a overexpression transgenic mice (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *X. WANG, M. A. CORTEZ, J. PERAZ VELAZQUEZ, C. LIU, L. SHEN, O. C. SNEAD, III; Dept Brain & Behav, Hosp. Sick Children, Toronto, ON, Canada Poster

38. (260.3/Q25) Cortical injury increases cholesterol 24s hydroxylase (cyp46) levels in the rat brain (Sunday, Nov 4 2007 3:00 PM - 4:00 PM) Abstract *C. M. CARTAGENA1, F. AHMED1, A. PAJOOHESH-GANJI1, D. T. PAK2, A. I. FADEN1, G. W. REBECK1; 1Dept Neurosci, 2Dept Pharm, Georgetown Univ., Washington, DC Poster

39. (260.4/Q26) ATP binding cassette transporter A1 (ABCA1) expression is upregulated in the mouse hippocampus following unilateral entorhinal cortex lesions (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *V. PEARSON1,2, S. BELANGER-JASMIN1,2, D. DEA1, L. THEROUX1, J. POIRIER1,2,3; 1Dept of Neurosci., Douglas Mental Hlth. Inst., Montreal, PQ, Canada; 2Dept. of Neurol. and Neurosurgery, McGill Univ., Montreal, PQ, Canada; 3McGill Ctr. for Studies in Ageing, Montreal, PQ, Canada Poster

40. (293.14/QQ5) Effect of manipulating developmental androgens and AR activation on hippocampal anatomy and hippocampal-dependent behavior performance (Sunday, Nov 4 2007 2:00 PM - 3:00 PM) Abstract *C. CHEN1, J. NUNEZ2; 1Psychology Dept., 2Psychology Department/Neurosci. Dept., Michigan State Univ., East Lansing, MI Poster

41. (309.12/DDD20) Estradiol replacement does not affect performance of ovariectomized rats on a water maze pattern completion task (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *J. BOHACEK1, N. A. HALAPIN1, J. CROSS-CALL2, J. M. DANIEL3; 1Dept Neurosci, 2Psychology, 3Psychology and Neurosci., Tulane Univ., New Orleans, LA Poster

42. (314.4/GGG24) Regulation of CNS alpha-estrogen receptor by two subcutaneous delivery systems of estradiol (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract *L. MOSQUERA, L. AROCHO, A. TORRADO, Y. TORRES, J. MIRANDA, A. SEGARRA; Univ. of PR, Sch. of Med., San Juan, Puerto Rico Poster

43. (315.4/HHH4) Mass spectral analysis of recombinant vesicular glutamate transporter protein after reconstitution into liposomes (Sunday, Nov 4 2007 4:00 PM - 5:00 PM) Abstract C.-K. CHAO1, S. A. PATEL1, *C. M. THOMPSON2; 1Biomed. and Pharmaceut. Sci., Univ. of Montana, Missoula, MT; 2Prof Med. Chem., Univ. Montana, Missoula, MT Poster

44. (331.3) An inhibitor of ceramide transport for sphingomyelin synthesis selectively increases abeta 42 secretion by SH-SY5Y overexpressing the amyloid precursor protein (Monday, Nov 5 2007 8:30 AM - 8:45 AM) Abstract *C. V. ZERBINATTI, S. SUON, M. YOUNG, G. R. SEABROOK, W. J. RAY; Dept Alzheimer's Res., Merck & Co., West Point, PA Slide

45. (331.7) Expression of cholesterol related genes is up-regulated in the Tg2576 mouse model of Alzheimer's disease (Monday, Nov 5 2007 9:30 AM - 9:45 AM) Abstract *H. K. WARWICK1, T. A. COMERY1, S. ASCHMIES1, E. KOURANOVA1, R. H. RING1, M. FOLLETTIE2, L. WANG2, A. HILL2, Y. KIRKSEY1, P. H. REINHART1, D. R. RIDDELL1; 1Discovery Neurosci., Wyeth Res., Monmouth Junction, NJ; 2Biol. Technologies, Wyeth Res., Cambridge, MA Slide

46. (350.20/F24) Peripheral benzodiazepine receptor distribution in the human brain postmortem (Monday, Nov 5 2007 11:00 AM - 12:00 PM) Abstract *A. BIEGON1,2, K. BARON-SELA4,2, M. WEISER4,3, N. ROZ5, M. REHAVI5; 1Med. Dept, Brookhaven Natl. Lab., Upton, NY; 2J. Sagol Neurosci. Ctr., 3Psychiatry, Sheba Med. Ctr., Ramat Gan, Israel; 5Physiology&Pharmacology, 4Tel Aviv Univ., Tel Aviv, Israel Poster

47. (354.1/G50) Cholesterol stabilizes the fusion pore of chromaffin granules before rapid dilation (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract N. WANG1,2, C. KWAN2, E. POSSE DE CHAVES1,2, *A. M. TSE1,2, F. W. TSE1,2; 1Dept Pharmacol, 2Ctr. for Neurosciences, Univ. Alberta, Edmonton, AB, Canada Poster

48. (354.6/H1) Cholesterol extraction disrupts cerebellar synaptic transmission(Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *A. J. SMITH, M. P. CHARLTON; Univ. Toronto, Toronto, ON, Canada Poster

49. (366.7/P2) Lrh-1/nr5a2: mediator of tau pathology via cholesterol regulation? (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *A. R. SYLVESTER, Y. M. GOZAL, J. LAH, A. I. LEVEY; Emory Univ., DECATUR, GA Poster

50. (367.13/Q6) Tau phosphorylation in lipid rafts in response to Abeta(25-35): involvement of Cdk5 (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract *P. A. HERNANDEZ1, G. LEE2, R. B. MACCIONI1; 1Biol., Univ. of Chile, Santiago, Chile; 2Intrnl. Med., The Univ. of Iowa, Iowa City, IA Poster

51. (368.5/Q26) Age-related changes in the composition of membrane microdomains might increase the susceptibility of mature hippocampal neurons to beta-amyloid-induced calpain-mediated neurotoxicity (Monday, Nov 5 2007 8:00 AM - 9:00 AM) Abstract *A. M. NICHOLSON, A. FERREIRA; Cell & Mol. Biol, Northwestern Univ., Chicago, IL Poster

52. (378.11/Y8) Microemboli composed of cholesterol disrupt the blood brain barrier and reduce cognitive function (Monday, Nov 5 2007 10:00 AM - 11:00 AM) Abstract *M. NEUMANN1, J. H. RAPP2, X. PAN2, S. HONG1, K. HOLLENBECK2, J. LIU1; 1Dept Neurosurgery, 2Dept Surgery, UCSF, VA Med. Ctr., San Francisco, CA Poster 53. (422.6/FFF28) ApoE4 affects spatial learning and memory in children (Monday, Nov 5 2007 9:00 AM - 10:00 AM) Abstract *S. F. ACEVEDO, J. RABER; Behav Neurosci, OHSU, Portland, OR Poster

54. (443.1) Effects of cholesterol oxidation products on exocytosis in pheochromocytoma-12 cells (Monday, Nov 5 2007 1:00 PM - 1:15 PM) Abstract *W. ONG; Dept Anat., Natl. Univ. Singapore, Singapore 119260, Singapore Slide

55. (444.4) Translational control of BACE1 in response to chronic energy deprivation (Monday, Nov 5 2007 1:45 PM - 2:00 PM) Abstract *T. L. O'CONNOR, E. MAUS, R. VASSAR; Cell & Mol. Biol, Northwestern Univ., Chicago, IL Slide

56. (448.6) Quantification and perturbation of the isoprenoids FPP and GGPP in mouse brain and primary neurons (Monday, Nov 5 2007 2:15 PM - 2:30 PM) Abstract D. A. VOLMER1, G. HOOFF2, G. P. ECKERT2, *W. G. WOOD3, W. E. MULLER2; 1HNR, Med. Res. Council, Cambridge, United Kingdom; 2Pharmacol., Univ. of Frankfurt, Frankfurt, Germany; 3Pharmacology/GRECC, Univ. Minnesota/VA Med. Ctr., Minneapolis, MN Slide

57. (458.22/D26) IL-6/sIL-6Ra chimera affects cerebral oligodendrocyte maturation and myelination in perinatal mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *S. H. BRUNSSEN1, J. GOHLKE2, A. D. TOEWS1, G. HARRY2; 1Univ. North Carolina- Chapel Hill, Chapel Hill, NC; 2NIEHS, NIH, DHHS, Research Triangle Park, NC Poster

58. (461.4/F20) Perturbation of cholesterol synthesis and trafficking affects retinal development and function (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract A. NIEMIEC, *T. CLAUDEPIERRE, K. NIEWEG, I. BUARD, F. PFRIEGER; Neurotransmission/secretion, Inst. Neurosci. Cell. Integ., Strasbourg, France Poster

59. (471.17/M4) Enrichment of cholesterol modulates ion channels via breakdown of phosphatidylinositol 4,5-bisphosphate (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract Y. CHUN1, S. SHIN1, M. PARK1, S. V. VORONOV2, T.-W. KIM2, G. DI PAOLO2, B.-C. SUH3, *S. CHUNG1; 1Dept Physiology, Sungkyunkwan Univ., Suwon, Republic of Korea; 2Dept. of Pathology, Columbia Univ. Med. Ctr., New York, NY; 3Dept. of Physiology and Biophysics, Univ. Washington Sch. of Med., Seattle, WA Poster

60. (472.4/M18) Pregnenolone sulfate increases glutamate release onto cerebellar Purkinje Cells (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *P. A. ZAMUDIO, M. CARTA, C. F. VALENZUELA; Neurosci., Univ. New Mexico, Albuquerque, NM Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

61. (474.2/N28) The effects of Statins on synaptic transmission and Aß-mediated attenuation of Long Term Potentiation (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract L. T. BREEN, A. CAMPOS-TORRES, *C. E. HERRON; Sch. Biomolecular & Biomed Sci., Univ. Coll Dublin, Dublin, Ireland Poster

62. (477.7/Q24) Sphingomyelinase suppresses hippocampal CA1 neuron excitability by inhibiting sodium currents (Monday, Nov 5 2007 3:00 PM - 4:00 PM) Abstract *E. D. NORMAN, R. CUTLER, M. MATTSON; Lab. Neurosci, Natl. Inst. Aging, Baltimore, MD Poster

63. (483.1/U1) High fat/high cholesterol diet-induced bace-1 expression and app processing (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract *L. THIRUMANGALAKUDI1, A. PRAKASAM2, S. MOHANTY2, K. SAMBAMURTI2, N. R. BHAT2; 2Neurosciences, 1Med. Univ. South Carolina, Charleston, SC Poster

64. (483.22/U22) Synaptic changes in the outer plexiform layer of the PDAPP/APOE4 double-transgenic mouse retina (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *J.-D. DING1, B. MACE2, R. HERRMANN1, P. SULLIVAN2, C. BOWES RICKMAN1,3; 1Ophthalmology, 2Med., 3Cell Biol., Duke Univ. Med. Ctr., Durham, NC Poster Session No.483: Alzheimer's Disease: Physiological Functions of APP and APP Metabolites II

65. (485.12/W7) Omega-3 fatty acid docosahexaenoic acid upregulates sorla/lr11, a sorting protein with reduced expression in sporadic Alzheimer disease (AD): potential for AD prevention (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *Q.-L. MA1,2, B. TETER1,2, T. MORIHARA3, O. J. UBEDA1,2, F. YANG1,2, W. BEECH1,2, G. P. LIM1,2, S. FRAUTSCHY1,2,4, G. M. COLE1,2,4; 1Sepulveda VA Med. Ctr., Greater Los Angeles Vets Affairs Hlth. Sys VA Med. Cntr, North Hills, CA; 2Dept. of Medicine, UCLA, North hills, CA; 3Psychiatry, Osaka Univ., Osaka, Japan; 4Dept. of Neurology, UCLA, North hills, CA Poster

66. (485.18/W13) Role of N-glycosylation in ACAT inhibition-mediated ER-associated degradation of APP (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *C. A. PEACH, C. A. BARREN, H. J. HUTTUNEN, D. M. KOVACS; MIND, Mass Gen Hosp/Harvard Med. Sch., Charlestown, MA Poster

67. (486.9/X3) Commonly used tool lxr agonists directly modulate ?-secretase activity (Monday, Nov 5 2007 1:00 PM - 2:00 PM) Abstract K. ATCHISON1, H. ZHOU1, Y. KIRKSEY1, *R. L. MARTONE2, M. N. PANGALOS1, P. H. REINHART1, S. JACOBSEN1, D. R. RIDDELL1; 1Wyeth Res., Princeton, NJ; 2Dept CNS Disorders, Wyeth-Ayerst Res., Princeton, NJ Poster

68. (486.14/X8) Molecular mechanisms underlying amyloid ß modulating effects of fenofibrate(Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract C. M. LILL, B. ZHANG, A. V. THOMAS, L. HERL, A. DENG, P. JONES, A. IVANOV, *M. GARCIA ALLOZA, B. T. HYMAN, O. BEREZOVSKA; MassGenl Inst. Neurodegen Dis., Massachusetts Genl Hosp., Boston, MA Poster

69. (490.10/AA11) Genetic modifiers of Niemann-Pick type C disease in mice (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *D. SYMULA1, K. COLLINS2,3, M. PEARCE2; 1Wadsworth Ctr. / Univ., Albany, NY; 2Wadsworth Ctr., Albany, NY; 3Univ. at Albany, Albany, NY Poster

70. (493.8/CC15) The small Rho-GTPase Rac1 is involved in lipid raft trafficking after oxygen glucose deprivation - Implications for dopamine receptor transport in astrocytes (Monday, Nov 5 2007 4:00 PM - 5:00 PM) Abstract *K. RUSCHER, M. RICKHAG, T. WIELOCH; Wallenberg Neurocentrum, Lab. for Exp Brain Res., Lund, Sweden Poster

71. (495.14/EE18) Steryl glycoside induced cytopathological changes in the motor neuron-derived NSC-34 cells (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *P. T. LY1,2, C. A. SHAW1,2,3; 1Exptl. Med., Univ. British Columb, Vancouver, BC, Canada; 2Ophthalmology & Visual Sci., 3Neurosci., Univ. of British Columbia, Vancouver, BC, Canada Poster

72. (519.22/XX5) Sex-dependent metabolic, neuroendocrine and cognitive responses to dietary energy restriction and excess (Monday, Nov 5 2007 2:00 PM - 3:00 PM) Abstract *B. MARTIN1, M. PEARSON1, L. KEBEJIAN1, E. GOLDEN1, A. KESELMAN1, M. BENDER1, O. CARLSON2, J. EGAN2, B. LADENHEIM4, J. CADET4, K. BECKER3, W. WOOD3, K. DUFFY5, P. VINAYAKUMAR3, S. MAUDSLEY1,6, M. P. MATTSON1,7; 1Lab. Neurosci, Natl. Inst. Aging, Baltimore, MD; 2Lab. Clin. Investigation, 3Gene Expression and Genomics Unit, Natl. Inst. on Aging Intramural Res. Program, Baltimore, MD; 4Mol. Neuropsychiatry Br., 5Lab. Exptl. Gerontology, Natl. Inst. on Drug Abuse, Baltimore, MD; 6Harbor Hosp., MedStar Res. Inst., Baltimore, MD; 7Dept. of Neurosci., Johns Hopkins Univ. Sch. of Med., Baltimore, MD Poster

73. (547.3) Regulation of membrane lipid metabolism by gamma-secretase (Tuesday, Nov 6 2007 8:30 AM - 8:45 AM) Abstract *J. G. WALTER1, K. PRAGER1, D. R. THAL2, K. THELEN3, T. WAHLE1, I. DEWACHTER4, P. ST. GEORGE-HYSLOP5, S. S. SISODIA6, D. LÜTJOHANN3, F. VAN LEUVEN4, I. Y. TAMBOLI1; 1Neurol , Mol. Cell Biol, 2Neuropathology, Univ. Bonn, Bonn, Germany; 3Clin. Pharmacol., Univ. of Bonn, Bonn, Germany; 4Human Genet., KU Leuven, Leuven, Belgium; 5Neurol., Univ. of Toronto, Toronto, ON, Canada; 6Neurobiology, Univ. of Chicago, Chicago, IL Slide

74. (547.6) Cholesterol and isoprenoids regulate amyloid production by different mechanisms (Tuesday, Nov 6 2007 9:15 AM - 9:30 AM) Abstract *K. SAMBAMURTI1, S. ANITHA2, C. VENUGOPAL1, A. PRAKASAM1,3, S. PAUL3, S. LIN3, Y. SU3, B. LIN3, Y. ZHOU4; 1Neurosciences, MUSC, Charleston, SC; 2Cancer Ctr., NJMS-UH, Newark, NJ; 3Eli Lilly and Co., Indianapolis, IN; 4Indiana University, Sch. of Med., Charleston, IN Slide

75. (550.9) Simvastatin upregulation of endothelin-1 increases Bcl-2 mRNA/protein levels and neuroprotection in neurons (Tuesday, Nov 6 2007 10:00 AM - 10:15 AM) Abstract *T. A. BUTTERICK1, L. N. JOHNSON-ANUNA2, G. P. ECKERT3, U. IGBAVBOA4, W. E. MULLER3, W. G. WOOD4; 1Pharmacol., Univ. of Minnesota, Minneapolis, MN; 2Tufts Univ., Boston, MA; 3Pharmacol., Univ. of Frankfurt, Frankfurt, Germany; 4Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide

76. (563.11/D7) Differentiation of human SH-SY5Y neuroblastoma cells cultured on microelectrode array plates (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract H. TEPPOLA1, J.-R. SARKANEN2, J. SELINUMMI1, A. PETTINEN1, *T. O. JALONEN3, M.-L. LINNE1; 1Inst. of Signal Processing, Tampere Univ. of Technol., Tampere, Finland; 2Fac. of Med., Univ. of Tampere, Tampere, Finland; 3Biol & Envrn. Sci. Nanosci Ctr., Univ. of Jyväskylä, Jyväskylä, Finland Poster

77. (570.11/G43) Lipid rafts and cell adhesion molecules in synapse formation (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *J. R. CONSTABLE, J. GIANG, P. E. WASHBOURNE; Inst. of Neurosci., Univ. of Oregon, Eugene, OR Poster

78. (571.3/G53) Role of lipid rafts in glia-induced synapse development (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *R. THIEBAUT1, F. W. PFRIEGER2; 1UMR 7168/LC2 CNRS ULP, 2Umr 7168/lc2 cnrs ulp, CNRS, Strasbourg, France Poster

79. (571.4/G54) Proteins secreted by astrocytes enhance inhibitory axon outgrowth, branching and synaptogenesis (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract *E. G. HUGHES1, S. B. ELMARIAH1, H. ISCHIROPOLOUS2,3, R. J. BALICE-GORDON1; 1Dept Neurosci, 2Dept of Pediatrics and Pharmacol., Univ. Pennsylvania, Philadelphia, PA; 3Children’s Hosp. of Pennsylvania, Philadelphia, PA Poster

80. (572.2/H24) Activation of adenosine A2A receptors increases TrkB receptors translocation to lipid rafts (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *N. ASSAIFE-LOPES1, D. B. PEREIRA2, J. A. RIBEIRO1, M. V. CHAO2, A. M. SEBASTIAO1; 1Inst. of Pharmacol and Neurosci, U. Lisbon,Fac. of Med. and IMM, Lisbon, Portugal; 2Lab. of Mol. Neurobiology, Skirball Inst. of Mol. Medicine, New York Univ., New York, NY Poster

81. (580.5/N8) Properties of synaptic transmission in Niemann-Pick type C1-deficient hippocampal neurons (Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *C. R. WASSER1, E. T. KAVALALI1,2; 1Dept. of Neurosci., 2Dept. of Physiology, UT Southwestern Med. Ctr., Dallas, TX Poster

82. (588.2/S17) Molecular manipulation of hippocampal astrocytes and effect on excitatory synapses (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract *E. V. JONES, K. K. MURAI; McGill Univ., Montreal, PQ, Canada Poster

83. (588.10/S25) Dendritogenesis and formation of excitatory synaptic input to Purkinje cells require glia, but not Npc1 (Tuesday, Nov 6 2007 9:00 AM - 10:00 AM) Abstract C. C. STEINMETZ, I. BUARD, *F. W. PFRIEGER; Neurotransmission/-secretion, Inst. Cell Integ Neurosci, Strasbourg Cedex, France Poster

84. (588.13/T2) Astrocyte-directed expression of wild type npc1 attenuates neuronal cholesterol storage and extends survival in npc1-/- mice(Tuesday, Nov 6 2007 8:00 AM - 9:00 AM) Abstract *M. ZHANG1, R. P. ERICKSON2, I. VINCENT3, J. L. HALLOWS4; 1Dept Neurol., Tongji Hosp., Wuhan, China; 2Dept. of Pediatrics, Univ. of Arizona, Tucson, AZ; 3Pediatrics, Univerisity of British Columbia, Vancouver, BC, Canada; 4Pediatrics, Univ. of British Columbia, Vancouver, BC, Canada Poster588. Glial-Neuronal Interactions: Regulation of Synapse Activity

85. (592.3/V11) The LXR agonist TO-901317 increases HMG-CoA reductase activity in vivo and in vitro (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *M. P. BURNS1, G. W. REBECK1, G. P. ECKERT2; 1Dept. of Neurosci., Georgetown Univ., Washington, DC; 2Dept. of Pharmacol., Univ. of Frankfurt, Frankfurt, Germany Poster

86. (592.16/V24) Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from cultured neurons (Tuesday, Nov 6 2007 11:00 AM - 12:00 PM) Abstract H. MINAGAWA1, A. WATANABE2, J.-S. GONG1, K. ZOU1, T. NAKAMURA1, S. LUND-KATZ3, M. C. PHILLIPS3, H. SAITO4, *M. MICHIKAWA1; 1Dept Alzheimer's Dis. Res., 2Dept Vascular Dementia Res., Natl. Centr Geriatrics Gerontol, Obu-shi, Japan; 3Children's Hosp. of Philadelphia, Univ. of Pennsylvania Sch. of Med., Philadelphia, PA; 4Dept. of Biophysical Chemistry, Kobe Pharmaceut. Univ., Kobe, Japan Poster

87. (600.19/BB15) Simvastatin, not atorvastatin, reduces macrophage invasion and astrogliosis after traumatic spinal cord injury (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *C. M. MANN1, Y. XIE1, J. H. LEE1, A. T. STAMMERS1, H. M. SOHN1, J. LIU1, D. SUTHERLAND1, C. K. LAM1, W. TETZLAFF1, B. K. KWON1,2; 1ICORD, 2Dept. of Orthopaedics, Univ. of British Columbia, Vancouver, BC, Canada Poster

88. (609.11/II24) The effects of ethanol on cholesterol transport proteins in adrenal and brain (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *K. N. BOYD1, T. D. IRONS2, S. KUMAR3, A. L. MORROW4; 1Toxicology, 2IBMS, 3Psychiatry, 4Psychiatry and Pharmacol., Univ. North Carolina, Chapel Hill, NC Poster

89. (625.3/UU21) Estrogen differentially affects leu-enkephalin and dynorphin immunoreactivity in the dorsal hippocampus of young, mature and old female rats (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *T. J. WILLIAMS1,2, A. TORRES-REVERON1, A. C. GORE3, B. MCEWEN4, T. A. MILNER1,4; 1Neurol and Neurosci, Weill Cornell Med. Coll, New York, NY; 2Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program, New York, NY; 3Div. of Pharmacol. and Toxicology, Univ. of Texas at Austin, Austin, TX; 4Harold and Margaret Milliken Hatch Lab. of Neuroendocrinology, The Rockefeller Univ., New York, NY Poster

90. (638.23/FFF15) Effects of cranial Cesium irradiation on neuronal markers in human apoE transgenic female mice (Tuesday, Nov 6 2007 10:00 AM - 11:00 AM) Abstract *L. E. VILLASANA1, C. POAGE1, T. PFANKUCH1, J. RABER1,2,3; 1Behav Neurosci, Oregon Hlth. & Sci. Univ., Portland, OR; 2Neurol., 3Div. of Neuroscience, ONPRC, OHSU, Portland, OR Poster

'Cholesterol' abstracts 1>30 | 31>60 | 61>90 | 91>126 | <CTRL><F> to search through this document

91. (658.7) Novel in vivo and mechanistic insights on the role ACAT inhibition in Aß generation (Tuesday, Nov 6 2007 2:30 PM - 2:45 PM) Abstract *H. J. HUTTUNEN1, B. HUTTER-PAIER2, C. A. PEACH1, C. A. BARREN1, M. WINDISCH2, D. M. KOVACS1; 1MIND, Mass Gen. Hosp/Harvard Med., Charlestown, MA; 2JSW Res., Graz, Austria Slide Session No. 658. Alzheimer's Disease: Anti-Abeta Therapies

92. (659.7) Cholesterol lowering agents reduce accumulation of alpha-synuclein in models of Parkinson's Disease (Tuesday, Nov 6 2007 2:30 PM - 2:45 PM) Abstract *A. O. KOOB1, P. BAR-ON1, E. ROCKENSTEIN1, L. CREWS2, A. ADAME1, E. MASLIAH1,2; 1Neurosciences, 2Pathology, UCSD, San Diego, CA Slide

93. (676.20/E37) Geranylgeranyl pyrophosphate is required for calcium-dependent catecholamine secretion(Tuesday, Nov 6 2007 4:00 PM - 5:00 PM) Abstract *E. TACHIKAWA1, H. TAIRA3, M. M. HOSSAIN4, Y. YOSHIOKA2, K. MIZUMA1, Y. KONDO1, S. GOTO1, Y. IRIE1, E. TAIRA1, H. NAKAGAWA5; 1Dept Pharmacol., 2High Field MRI Res. Insti, Advanced Med. Sci. Res. Cent, Iwate Med. Univ., Morioka, Japan; 3Fac. of Agr., Iwate Univ., Morioka, Japan; 4Cent Environ Hlth. Sci, Dept Basic Sci., Miss State Univ., Jackson, MS; 5Dept. of Life Sci., Univ. of Tokushima, Tokushima, Japan Poster

94. (689.15/K27) A low-density lipoprotein receptor isoform lacking exon 4 is present in low-density lipoprotein receptor knock-out mouse brain (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *J. F. ABISAMBRA1,2, J. PADMANABHAN1,2, I. WEFES2, P. NEAME1, H. POTTER1,2; 1Johnnie B. Byrd, Sr. Alzheimer's Ctr. & Res. Inst., Tampa, FL; 2Univ. of South Florida, Tampa, FL Poster

95. (690.3/L13) Dhcr7 downregulation results in complex transcriptome changes in Neuro2a cells (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *Z. KORADE1, A. KENWORTHY2, K. MIRNICS3; 1Dept. of Biochem., 2Dept. of Mol. Physiology and Biophysics, 3Dept. of Psychiatry, Vanderbilt Univ., Nashville, TN Poster

96. (690.7/L17) Direct regulation of gamma-secretase by its lipid microenvironment (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *P. OSENKOWSKI, W. YE, L. MORRIS-SMITH, M. S. WOLFE, D. J. SELKOE; Cntr for Neurologic Dis., Harvard Med. Sch., Boston, MA Poster Session No. 690. Alzheimer's Disease: Presenilin Function II

97. (701.7/T24) Potential role of apolipoprotein-E in clearance of apoptotic bodies (Tuesday, Nov 6 2007 3:00 PM - 4:00 PM) Abstract *D. A. ELLIOTT, W. S. KIM, B. GARNER; POWMRI, Randwick, Australia Poster

98. (725.17/MM18) Role of steroid receptor-mediated mechanisms at the level of the amygdala in the regulation of anxiety and visceral pain (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *B. MYERS, B. GREENWOOD-VAN MEERVELD; Univ. Oklahoma HSC, Oklahoma City, OK Poster

99. (732.1/RR3) 17ß-estradiol and cholesterol silastic implants prevent chronic stress-induced hippocampal CA3 dendritic retraction in ovariectomized female rats (Tuesday, Nov 6 2007 1:00 PM - 2:00 PM) Abstract *K. J. MCLAUGHLIN, J. S. HARMAN, R. HAJO, J. GOMEZ, C. D. CONRAD; Psych, Behavioral Neurosci, Arizona State Univ., Tempe, AZ Poster

100. (743.2/AAA25) Memory impairment occurred in mice deficient for lipoprotein lipase is probably caused by decrease of pre-synaptic vesicles (Tuesday, Nov 6 2007 2:00 PM - 3:00 PM) Abstract *D. CHUI1, T.-T. LIU1, X. XIAN2, J. YU1, Y. MIAO1, Y. YU1, G. LIU2; 1NeuroScience Resch Inst., Peking Univ., Beijing, China; 2Inst. of Cardiovascular, Peking Univ., Beijing, China Poster Session No. 743: Cognitive Learning and Memory Systems VII

101. (763.12) A rabbit eyeblink conditioning model for Alzheimer's disease treatment research (Wednesday, Nov 7 2007 10:45 AM - 11:00 AM) Abstract *C. J. MCKINNEY1,2, M. T. ALLEN2; 1Applied Stats & Rsch Mtds, Univ. Northern Colorado, Greeley, CO; 2Sch. of Psychological Sci., Univ. of Northern Colorado, Greeley, CO Slide Session No.763: Alzheimer's Disease and Other Dementias: Experimental Models II

102. (763.13) Hypercholesterolemia-induced alteration in insulin signaling: Implications in a model for sporadic Alzheimer’s Disease (Wednesday, Nov 7 2007 11:00 AM - 11:15 AM) Abstract *S. SHARMA, G. FEIST, B. SIEFKEN, O. GHRIBI; Dept Physiol Pharmacol & Therap, Univ. North Dakota Sch. Med., Grand Forks, ND Slide Session No. 763: Alzheimer's Disease and Other Dementias: Experimental Models II

103. (785.5/G38) Effects of membrane cholesterol disruption on IP3-mediated calcium liberation (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *S. M. WILTGEN, I. F. SMITH, I. PARKER; Neurobiology and Behavior, Univ. California, Irvine, Irvine, CA Poster

104. (795.9/N1) Changes in the expression of genes involved in cholesterol trafficking with the progression of Alzheimer’s disease (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *A. AKRAM1, P. KATSEL1, P. HOF2, V. HAROUTUNIAN1; 1Psychiatry, 2Neurosci., Mount Sinai Sch. of Med., New York, NY Poster Session No.795: Alzheimer's Disease and Other Dementias: Genetics and Functional Genomics

105. (795.17/N9) The association of cholesterol levels and APOE promoter polymorphism with vascular dementia (Wednesday, Nov 7 2007 8:00 AM - 9:00 AM) Abstract *F. LIU1, W.-D. XU2, C. JIA2, J. LI3; 1Dept Neurol., Fengtian Hosp Shenyang Med. Col., Shenyang, China; 2Fengtian Hosp. of Shenyang Med. Col., Shenyang, China; 3China Med. Univ., Shenyang, China Poster

106. (800.19/R16) Apolipoprotein E-mimetic peptides promote the survival and proliferation of oligodendrocyte precursor cells in vitro and remyelination in vivo (Wednesday, Nov 7 2007 10:00 AM - 11:00 AM) Abstract *F.-Q. LI1,2, J. E. NEIL2, C. A. COLTON1, M. P. VITEK1,2; 1Dept Med., Duke Univ. Med. Ctr., Durham, NC; 2Cognosci, Inc., Research Triangle Park, NC Poster

107. (807.22/X21) Cerebellar lipids in mice with Rett Syndrome (Wednesday, Nov 7 2007 9:00 AM - 10:00 AM) Abstract K. A. HEINECKE, J. G. MANTIS, *T. N. SEYFRIED; Dept Biol, Boston Col., Chestnut Hill, MA Poster

108. (823.4/HH2) Enhanced expression of peripheral-type benzodiazepine receptor induces neuropathic pain (Wednesday, Nov 7 2007 11:00 AM - 12:00 PM) Abstract *T. TANABE, D. KONDO, R. YABE, I. TAKASAKI, T. KURIHARA, H. SAEGUSA, S. ZONG; Dept Pharmacol/Neurobiol, Tokyo Med. & Dent. Univ. Grad Sch. Med., Tokyo, Japan Poster

109. (856.12) Amyloid beta-protein stimulates retrograde transport of cholesterol and caveolin from the plasma membrane to the Golgi complex in mouse primary astrocytes (Wednesday, Nov 7 2007 3:45 PM - 4:00 PM) Abstract *U. F. IGBAVBOA1, W. G. WOOD2; 1Dept of Pharmacol, Univ. of MN- VA Med. Ctr., Minneapolis, MN; 2Pharmacol., Univ. of Minnesota, Minneapolis, MN Slide Session No. 856. Abeta Toxicity

110. (857.5) Expression of ABC transporters in the human brain and their impact on cholesterol efflux and amyloid-beta processing (Wednesday, Nov 7 2007 2:00 PM - 2:15 PM) Abstract *W. S. KIM1, S. L. CHAN1, A. F. HILL2, B. GARNER1; 1Prince of Wales Med. Res. Inst., Sydney, Australia; 2Dept. of Biochem. and Mol. Biol., Univ. of Melbourne, Melbourne, Australia Slide Session No. 857: Abeta Degradation and Clearance

111. (878.13/G33) GPR50: an orphan G protein-coupled receptor implicated in psychiatric illness and cholesterol metabolism (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *P. A. THOMSON1, H. L. KINNELL2, E. GRÜNEWALD2, D. H. R. BLACKWOOD2,3, D. J. PORTEOUS2; 1Univ. of Edinburgh, Edinburgh, ; 2Univ. of Edinburgh, Edinburgh, United Kingdom; 3Royal Edinburgh Hosp., Edinburgh, United Kingdom Poster Session No. 878: G-Protein Coupled Receptors: Other

112. (880.4/H13) Modulation of dopamine transporter cellular localization and protein conformation by membrane cholesterol (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *W. HONG, S. G. AMARA; Dept Neurobiol, Univ. Pittsburgh, Pittsburgh, PA Poster Session No.880. Transporters: Dopamine II

113. (880.5/H14) Membrane raft association and posttranslational fatty acid modification of the dopamine transporter (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *J. D. FOSTER, S. D. ADKINS, R. A. VAUGHAN; Biochem & Molec Biol, Univ. N Dakota Sch. Med. & Hlth. S, Grand Forks, ND Poster

114. (880.6/H15) AMPH and METH partition hDAT into different plasma membrane microdomains (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *H. KHOSHBOUEI1, N. SEN3, J. A. JAVITCH3, J. S. GOODWIN2; 1Dept Biol. Sci., 2Dept Biomed. Sci., Meharry Med. Coll, Nashville, TN; 3Departments of Psychiatry and Pharmacol., Ctr. for Mol. Recognition, Columbia University College of Physicians and Surg, NY Poster

115. (884.6/K4) Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *G. BU, Q. LIU; Washington Univ., St. Louis, MO Poster Session No.884: Alzheimer's Disease: Physiological Functions of APP and APP Metabolites III NoL related items: 1 | 2

116. (885.5/K26) Domains in LRP cytoplasmic tail in Aß generation and trafficking of APP to lipid rafts (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *E. C. CHEN, M. K. LAKSHMANA, I. YOON, E. H. KOO, D. E. KANG; Dept. Neurosciences, UCSD, La Jolla, CA Poster Session No.885: Alzheimer's Disease: APP Processing

117. (885.9/L2) Monitoring Amyloid Precursor Protein (APP) and Beta-Secretase interaction in living cells by Total internal reflection energy transfer (TIRET) microscopy (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *C. A. VON ARNIM1, B. VON EINEM1, D. SCHWANZAR1, M. WAGNER2, P. WEBER2, H. SCHNECKENBURGER2; 1Dept Neurol, Univ. Ulm, 89075 Ulm, Germany; 2Inst. für Angew. Forschung, Hochschule Aalen, Aalen, Germany Poster Session No.885: Alzheimer's Disease: APP Processing <>

118. (886.7/L23) Downstream effects of statins on amyloid precursor protein processing and Aß secretion (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract N. POZDNYAKOV, C. E. OBORSKI, B. A. MARTIN, M. A. COLLINS, J. E. FINLEY, K. L. TODD, R. B. NELSON, D. R. LISTON, H. J. HARWOOD, B. TATE, *L.-F. LAU; CNS Discovery, Pfizer Global Res. & Dev, Groton, CT Poster Session No.886: Alzheimer's Disease: Anti-Abeta Treatments II

119. (890.13/P13) A consecutive analysis of biochemical markers associated with Alzheimer's disease (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract *S. CULLEN1, P. CARMONEY2; 1Walden Univ., Parker, CO; 2Walden Univ., Minneapolis, MN Poster

120. (893.13/R22) Inhibition of activity of plasma membrane ganglioside sialidase (PMGS) and disruption of lipid rafts attenuates ability of axons to regenerate (Wednesday, Nov 7 2007 1:00 PM - 2:00 PM) Abstract S. KAPPAGANTULA, *J. W. FAWCETT; Ctr. Brain Repair, Cambridge Univ., Cambridge, United Kingdom Poster Session No.893: Parkinson's Disease: Circuits

121. (896.8/T24) Altered levels of endosomal-lysosmal markers in NPC knock-out mouse brains (Wednesday, Nov 7 2007 4:00 PM - 5:00 PM) Abstract *A. AMRITRAJ1, K. PEAKE2, A. KODAM1, J. E. VANCE2, S. KAR3; 1Dept of Psychiatry, 2Dept of Med., 3Dept of Psychiatry and Dept of Med., Univ. Of Alberta, Edmonton, AB, Canada Poster

122. (896.14/U2) Intraventricular infusion of recombinant human acid sphingomyelinase as a potential treatment for Niemann-Pick A disease (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract J. CLARKE, C. TRELEAVEN, T. TAKSIR, D. GRIFFITHS, W. YANG, J. BU, S. CHENG, *L. S. SHIHABUDDIN, J. DODGE; Dept Neurosci., Genzyme Corp, Framingham, MA Poster

123. (897.6/U10) Anti-inflammatory agents as theraptic potential in Niemann Pick type C disease (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract W. GONG, P. HOANG, *S. H. MELLON; Ob/Gyn, Univ. California San Francisco, San Francisco, CA Poster Session No.897: Neurodegenerative Disorders: Oxidative Stress and Inflammation

124. (900.10/X10) Paraoxonase gene polymorphisms and lipid profile in Korean ischemic stroke patients (Wednesday, Nov 7 2007 2:00 PM - 3:00 PM) Abstract *B. SHIN1,3, Y. KIM3, S. OH4, S. JEONG4, K. KIM2; 1Neurol., 2Pharmacol., Chonbuk Natl. Univ., Jeonju, Republic of Korea; 3Chonbuk Natl. Univ. Hosp. Res. Inst. of Clin. Med., Jeonju, Republic of Korea; 4Chonbuk Natl. Univ. Hosp., Jeonju, Republic of Korea Poster

125. (902.3/Y28) Atorvastatin prevent apoptosis after a thoracic spinal cord contusion injury and promotes locomotion recovery (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *E. BEAUMONT1, G. ROUSSEAU2, M. BENDERDOUR2; 1Surgery, 2Pharmacol., Univ. of Montreal, Montreal, PQ, Canada Poster Session No.902: Spinal Therapeutic Strategy

126. (932.15/WW10) Effect of the ABCG1 cholesterol transporter on cognition and Alzheimer Disease (Wednesday, Nov 7 2007 3:00 PM - 4:00 PM) Abstract *P. F. PARKINSON, B. L. BURGESS, T. S. KANNANGARA, B. R. CHRISTIE, C. L. WELLINGTON; UBC, Vancouver, BC, Canada Poster Session No.932: Cognitive Learning and Memory Systems IX

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'Phospholipid' abstracts 1>30 | 31>50 | <CTRL><F> to search through this document

1. (43.3/H4) Oxidative downmodulation of Kv1.4- and Kv4.2-mediated K+-currents by arachidonic acid in transfected HEK 293 cells (Saturday, Nov 3 2007 3:00 PM - 4:00 PM) Abstract *P. R. ANGELOVA1, W. S. MUELLER2; 1Neurophysiol, Charite Med. Sch., Berlin, Germany; 2Neurosurgery, Univ. of New Mexico Med. Sch., Albuquerque, NM Poster

2. (61.16/W8) PRKCB1 and autism: reduced gene expression in the temporal cortex of autistic brains, and significant association between PRKCB1 gene variants and autistic disorder (Saturday, Nov 3 2007 4:00 PM - 5:00 PM) Abstract *A. M. PERSICO1,2, C. LINTAS1,2, R. SACCO1,2, L. GAITA1,2, R. D'ORONZIO1,2, K. GARBETT3, K. MIRNICS3,4, R. MILITERNI5, C. BRAVACCIO6, P. CURATOLO7, B. MANZI7, C. SCHNEIDER8, R. MELMED9, M. ELIA10; 1Lab. Mol Psychiat & Neurogen, Univ. Campus Bio-Medico, Rome, Italy; 2IRCCS "Fondazione S.Lucia", Rome, Italy; 3Dept. of Psychiatry, Vanderbilt Univ., Nashville, TN; 4Kennedy Ctr. for Res. on Human Develop. at Vanderbilt Univ., Nashville, TN; 5Child Neuropsychiatry